• @About this App Makindo
  • @Contributers
  • @Developer and Author
  • @Join Team Makindo
  • @Makindo Questions
  • @Privacy and Data Policy
  • ACTH (Adrenocorticotropic hormone)
  • AF and Anticoagulation ✅
  • AFP (Alpha-fetoprotein) Testing
  • AIDS (HIV) Neurological Disease
  • AIDS (HIV) Respiratory disease
  • AIDS Dementia Complex (HIV) ✅
  • AIDS HAART Antiretroviral Drugs ✅
  • AIDS HIV Infection and a Fever ✅
  • AIDS(HIV) Gastrointestinal Disease ✅
  • APGAR Scoring (Children)
  • APTT and Coagulation
  • Abacavir 💊
  • Abatacept 💊
  • Abbey Pain Scale
  • Abbreviated Mental Test Score (AMTS)
  • Abciximab 💊
  • Abdominal Aortic Aneurysm (AAA) ✅
  • Abdominal Distension
  • Abdominal Mass (Child health)
  • Abdominal Masses: Clinical Approach and Considerations
  • Abdominal X Ray Collections
  • Abdominal X-Ray (AXR)
  • Abdominal paracentesis for ascites
  • Abducent Nerve (Cranial Nerve VI)
  • Abetalipoproteinemia (Bassen-Kornzweig Syndrome)
  • Abnormal Involuntary Movements
  • Abnormal eating exercising behaviour (Children)
  • Abnormal urinalysis
  • Abscess - General
  • Absence Seizure
  • Acamprosate 💊
  • Acanthocytes
  • Acanthosis Nigricans
  • Acarbose 💊
  • Accelerated Idioventricular Rhythm ❤️
  • Accessory Nerve (Cranial Nerve XI)
  • Acetazolamide 💊
  • Acetylcholine Receptor Antibodies
  • Acetylcholinesterase inhibitors
  • Achalasia
  • Achenbach’s syndrome
  • Achilles Tendon rupture
  • Achondroplasia ✅
  • Aciclovir 💊
  • Acid maltase deficiency (Pompe disease)
  • Acid-Base abnorrmalities
  • Acne Vulgaris ✅
  • Acoustic Neuroma ✅
  • Acquired Long QT syndrome (LQTS)
  • Acrodermatitis enteropathica (Children)
  • Acromegaly and Giantism ✅
  • Acromio-clavicular joint
  • Actinic Keratosis
  • Actinomyces israeli
  • Action Potential Neuron Versus Cardiac Ventricular Myocyte
  • Activated Charcoal
  • Active Proctitis ✅
  • Actrapid (Insulin) 💊
  • Acute (Ascending) Cholangitis ✅
  • Acute Abdomen - Perforation of a Viscus
  • Acute Abdominal Pain (OSCE focused)
  • Acute Abdominal Pain - Children ✅
  • Acute Abdominal Pain in Adults
  • Acute Acalculous Cholecystitis✅
  • Acute Airway Obstruction
  • Acute Anaphylactoid Reactions
  • Acute Anaphylaxis ✅
  • Acute Appendicitis (OSCE focused)
  • Acute Appendicitis in Children ✅
  • Acute Appendicitis ✅
  • Acute Bacterial Meningitis (Adults) ✅
  • Acute Bacterial Meningitis in Children ✅
  • Acute Bacterial Prostatitis ✅
  • Acute Blepharitis 👁️
  • Acute Bronchitis ✅
  • Acute Cardiogenic Pulmonary Oedema (CPO/LVF) ❤️
  • Acute Change in Vision or Vision Loss (OSCE focused)
  • Acute Chest Syndrome (Sickle Cell) ✅
  • Acute Cholecystitis ✅
  • Acute Colonic Pseudo-obstruction
  • Acute Compartment Syndrome
  • Acute Coronary Syndrome (ACS) NSTEMI USA ❤️ ✅
  • Acute Coronary Syndrome (ACS) STEMI ❤️ ✅
  • Acute Coronary Syndrome (ACS): Chest Pain ❤️ ✅
  • Acute Coronary Syndrome (ACS): Complications
  • Acute Coronary Syndrome Grace score ❤️
  • Acute Coronary Syndrome TIMI Score
  • Acute Coronary Syndrome: Cardiac Thrombolysis ❤️
  • Acute Coronary Syndrome: LBBB and AMI
  • Acute Coronary Syndrome: Overview
  • Acute Coronary Syndrome: Unstable Angina
  • Acute Coronary: Percutaneous Coronary Intervention
  • Acute Delirium
  • Acute Disc Prolapse
  • Acute Disseminated Encephalomyelitis
  • Acute Dystonic Reaction
  • Acute Encephalitis ✅
  • Acute Eosinophilic Pneumonia
  • Acute Epiglottitis
  • Acute Exacerbation of COPD✅
  • Acute Fatty Liver of Pregnancy
  • Acute Glaucoma
  • Acute Glomerulonephritis in Children ✅
  • Acute Hepatic Porphyrias ✅
  • Acute Hepatitis and Acute Liver disease
  • Acute Hydrocephalus
  • Acute Hypotension ✅
  • Acute Inflammation
  • Acute Intermittent Porphyria (AIP)
  • Acute Interstitial nephritis
  • Acute Joint Pain and Swelling (Children)
  • Acute Kidney Injury ✅
  • Acute Limb Ischaemia
  • Acute Liver Disease & Acute Liver Failure ✅
  • Acute Lymphangitis
  • Acute Lymphoblastic Leukaemia (ALL) ✅
  • Acute Medicine and resuscitation
  • Acute Medicine: Laboratory Results
  • Acute Medicine: Poisoning and toxicology
  • Acute Monoarthritis
  • Acute Myeloblastic Leukaemia (AML) ✅
  • Acute Myocarditis ✅
  • Acute Neck Injury (no fracture)
  • Acute Necrotizing Ulcerative Gingivitis
  • Acute Pancreatitis ✅
  • Acute Pericarditis ✅
  • Acute Phase reactants
  • Acute Promyelocytic Leukaemia (APML)
  • Acute Psychosis / Agitation
  • Acute Pyelonephritis and Urosepsis (UTI) ✅
  • Acute Radiation Syndromes
  • Acute Renal / Ureteric Colic and Urinary Tract Stones ✅
  • Acute Respiratory Distress Syndrome (ARDS)✅
  • Acute Retroviral Syndrome (HIV)
  • Acute Rhabdomyolysis ✅
  • Acute Right-Sided Weakness (OSCE focused) 🧠
  • Acute Rotator Cuff Tear ✅
  • Acute Severe Asthma (Status Asthmaticus)✅
  • Acute Severe Colitis
  • Acute Stroke Care Guidance UK Ireland 2023
  • Acute Tracheitis
  • Acute Urinary Retention
  • Acute Uterine Haemorrhage ✅
  • Acute and Chronic Diarrhoea ✅
  • Acute and Chronic Gout ✅
  • Acute on Chronic Liver Disease Decompensation
  • Acute rash (Child Health)
  • Acutely Ill Critical care patient with High NEWS
  • Acutely Ill Patient with Parkinson's disease
  • Adalimumab 💊
  • Addenbrooke's Cognitive Examination-Revised (ACER)
  • Addison Disease (Adrenal Insufficiency)
  • Adefovir 💊
  • Adenocarcinoma of the Ampulla of vater
  • Adenosine deaminase deficiency
  • Adenosine 💊
  • Adhesive Capsulitis (Frozen Shoulder) ✅
  • Administer IV Injection
  • Adrenal Adenomas
  • Adrenal Cancer
  • Adrenal Masses Incidentalomas
  • Adrenal crises (Paediatric) ✅
  • Adrenaline (Epinephrine) 💊
  • Adrenoleukodystrophy
  • Adrenomyeloneuropathy
  • Adult Hypertension ✅
  • Adult Onset Stills Disease
  • Adult Polycystic kidney disease ✅
  • Adverse Drug Effects
  • African Trypanosomiasis (Sleeping sickness)
  • Age-Related Macular Degeneration (ARMD)
  • Aicardi syndrome
  • Air Embolism ✅
  • Alberta Stroke program Early CT score (ASPECT) scoring system
  • Albumin
  • Albumin-Protein Creatinine Ratio (PCR)
  • Alcohol Metabolism
  • Alcohol Withdrawal (Delirium Tremens)
  • Alcoholic Hepatitis
  • Alcoholic Ketoacidosis
  • Aldosterone
  • Alendronate (Alendronic acid) 💊
  • Alfacalcidol 💊
  • Algorithms
  • Alkaline phosphatase (ALP)
  • Alkalinisation of urine
  • Alkaptonuria
  • Allergic Bronchopulmonary Aspergillosis
  • Allergic Rhinitis
  • Allergic disorders
  • Allergies
  • Allogeneic stem cell transplantation
  • Allopurinol 💊
  • Alogliptin (Vipidia) 💊
  • Alopecia Areata
  • Alopecia ✅
  • Alpha Thalassaemia ✅
  • Alpha subunit (ASU) of TSH
  • Alpha-1 Antitrypsin (AAT) deficiency
  • Alpha-gal syndrome
  • Alport's Syndrome
  • Alteplase 💊
  • Altitude sickness / Acute Mountain sickness
  • Aluminium and Magnesium Antacids
  • Alveolar Gas Equation
  • Alzheimer disease (Dementia) ✅
  • Amantadine 💊
  • Amaurosis fugax
  • Amblyopia 👁️
  • Ameloblastoma
  • Amenorrhoea
  • American Trypanosomiasis (Chagas Disease)
  • Amiloride
  • Amino acids
  • Aminoglycosides 💊
  • Aminophylline 💊
  • Aminosalicylates 💊
  • Amiodarone and Thyroid disease
  • Amiodarone 💊
  • Amitriptyline 💊
  • Amlodipine 💊
  • Ammonia Encephalopathy
  • Amnestic syndromes and Memory Disorders
  • Amoebiasis Amoebic (Entamoeba histolytica)
  • Amoxicillin 💊
  • Amphetamine toxicity⚠️
  • Amphotericin B 💊
  • Ampicillin 💊
  • Amputations
  • Anaemia (Child Health)
  • Anaemia (Pregnancy)
  • Anaemia in Chronic Kidney Disease
  • Anaemia of Chronic Disease ✅
  • Anaemia: Assessment ✅
  • Anaesthetics and Critical Care Revision Guide ✅
  • Anagrelide 💊
  • Anakinra 💊
  • Anal Cancer ✅
  • Anal Fissure
  • Analgesic Nephropathy
  • Anaromy and Physiology of the Brain
  • Anatomy and Phsyiology of the Ear
  • Anatomy and Physiology of the Pituitary
  • Anatomy and Physiology of Cilia
  • Anatomy and Physiology of Female Genitalia and Reproduction
  • Anatomy and Physiology of Male Genitalia
  • Anatomy and Physiology of Nerves
  • Anatomy and Physiology of Ribs and Chest Wall
  • Anatomy and Physiology of Small Bowel
  • Anatomy and Physiology of the Abdomen
  • Anatomy and Physiology of the Adrenal Gland
  • Anatomy and Physiology of the Basal Ganglia
  • Anatomy and Physiology of the Biliary system
  • Anatomy and Physiology of the Bladder
  • Anatomy and Physiology of the Bone Marrow
  • Anatomy and Physiology of the Brainstem
  • Anatomy and Physiology of the Breast
  • Anatomy and Physiology of the Cauda equina
  • Anatomy and Physiology of the Cerebellum
  • Anatomy and Physiology of the Cerebral Cortex
  • Anatomy and Physiology of the Coronary Arteries
  • Anatomy and Physiology of the Diaphragm
  • Anatomy and Physiology of the Eye
  • Anatomy and Physiology of the Glomerulus
  • Anatomy and Physiology of the Heart
  • Anatomy and Physiology of the Kidneys
  • Anatomy and Physiology of the Large Bowel (Colon, Rectum, Anal Canal)
  • Anatomy and Physiology of the Larynx
  • Anatomy and Physiology of the Liver
  • Anatomy and Physiology of the Lungs
  • Anatomy and Physiology of the Nose
  • Anatomy and Physiology of the Oesophagus
  • Anatomy and Physiology of the Ovary
  • Anatomy and Physiology of the Pancreas
  • Anatomy and Physiology of the Parathyroid Gland
  • Anatomy and Physiology of the Pelvis
  • Anatomy and Physiology of the Pharynx
  • Anatomy and Physiology of the Rectum
  • Anatomy and Physiology of the Spinal Cord
  • Anatomy and Physiology of the Spine
  • Anatomy and Physiology of the Spleen
  • Anatomy and Physiology of the Stomach
  • Anatomy and Physiology of the Thorax
  • Anatomy and Physiology of the Thymus Gland
  • Anatomy and Physiology of the Thyroid Gland
  • Anatomy and Physiology of the Uterus and Fallopian Tubes
  • Anatomy and Physiology of the Vascular System
  • Anatomy and Physiology of the vagina
  • Anatomy and Physiology: Human
  • Anatomy of Cells and Physiology
  • Anatomy of Dentistry
  • Anatomy of the Hand
  • Anatomy of the Inguinal and Femoral canal
  • Anatomy of the Muscles
  • Anatomy of the Skin
  • Anatony and Physiology of the Nephron
  • Andexanet alfa
  • Androgen insensitivity syndrome
  • Aneurysms, ischaemic limb and occlusions
  • Angina bullosa haemorrhagica
  • Angiodysplasia
  • Angiomyolipoma
  • Angioneurotic Oedema
  • Angiotensin Converting Enzyme Inhibitors
  • Angiotensin Converting enzyme (ACE) 💊
  • Angular Stomatitis - Cheilitis
  • Anion Gap and Metabolic Acidosis
  • Ankle-Brachial Pressure Index (OSCE focused)
  • Ankylosing spondylitis
  • Anogenital Warts (HPV) ✅
  • Anomalous Coronary Arteries
  • Anorexia Nervosa
  • Anosmia
  • Antacid medication
  • Anterior / Medial Medullary Infarct (Dejerine Syndrome)
  • Anterior Choroidal Artery Ischaemic Stroke
  • Anterior Cruciate ligament injury
  • Anterior Horn Cell diseases
  • Anterior Spinal Cord syndrome
  • Anterior circulation Brain
  • Anthrax (Bacillus anthracis)
  • Anti microbial stewardship ✅
  • Anti-Citrullinated Protein Antibody (ACPA)
  • Anti-D immunoglobulin
  • Anti-Hu antibodies
  • Anti-NMDA (NMDAR) receptor encephalitis
  • Anti-OKT3 antibodies
  • Anti-RNP Antibody
  • Anti-Yo antibodies
  • Anti-neutrophilic cytoplasmic antibodies (ANCA)
  • Antiarrhythmic agents
  • Antibiotic Guidelines✅
  • Antibiotics Mechanisms
  • Antibiotics for Abdominal Infections
  • Anticholinergic Burden
  • Anticholinergic syndrome
  • Anticipation
  • Anticoagulation and Antithrombotic
  • Antidiuretic hormone (Vasopressin)
  • Antigen presenting cells
  • Antimicrobial Choices
  • Antimicrobial agents
  • Antimuscarinic drugs 💊
  • Antiphospholipid Syndrome
  • Antithrombin III deficiency (AT3)
  • Anuria and Oliguria
  • Anxiety Phobias and OCD
  • Anxiety disorder: generalised (GAD)
  • Aortic Dissection ✅
  • Aortic Regurgitation ✅
  • Aortic Sclerosis
  • Aortic Stenosis ✅
  • Aortoenteric fistula
  • Apathetic thyrotoxicosis
  • Apixaban 💊
  • Aplastic anaemia ✅
  • Apomorphine 💊
  • Apoptosis
  • Appendix Cancer Tumours
  • Approach to the Child with Respiratory Distress
  • Apraxia
  • Arachnoid cyst
  • Arnold Chiari malformation
  • Arrhythmias
  • Arrhythmogenic Right Ventricular Cardiomyopathy
  • Artemisinins 💊
  • Arterial blood gas sampling
  • Arterial thrombosis
  • Arteriovenous Malformations
  • Artery of Percheron stroke
  • Artery-to-artery embolic stroke
  • Artesunate
  • Arthritis Diagnosis Compared
  • Arthrocentesis and Synovial fluid analysis
  • Asbestos Related Lung disease
  • Ascites ✅
  • Aspergilloma
  • Aspergillus fumigatus
  • Aspirin 💊
  • Aspirin/Salicylate Toxicity
  • Assessing Hearing Loss
  • Assessing Significance
  • Assessing a Patient who is Shocked
  • Assessing and Painful Red eye
  • Assessment of Causes of Nausea 🤢
  • Assessment of causes of Vaginal Discharge
  • Asteatotic eczema
  • Asthma COPD overlap syndrome
  • Asthma✅
  • Astigmatism
  • Astrocytomas
  • Ataxia Telangiectasia
  • Atazanavir 💊
  • Atenolol 💊
  • Atherosclerosis ❤️
  • Atorvastatin 💊
  • Atracurium
  • Atrial Ectopic beats
  • Atrial Fibrillation and Rhythm Control ✅
  • Atrial Natriuretic Peptide (ANP)
  • Atrial myxoma ❤️
  • Atrial septal defect (ASD) ✅
  • Atrioventricular Block
  • Atrioventricular Nodal Reentrant Tachycardia AVNRT ❤️
  • Atrophic vaginitis
  • Atropine Sulfate 💊
  • Attention deficit hyperactivity disorder
  • Auditory hallucinations
  • Autism spectrum disorder
  • Autoimmune Haemolytic anaemia (AIHA) ✅
  • Autoimmune Hepatitis ✅
  • Autoimmune Liver Disease Table ✅
  • Autoimmune Polyendocrine Syndromes
  • Automatic Implantable Cardioverter Defibrillator (AICD)
  • Autonomic Nervous System
  • Autonomic neuropathy ✅
  • Autosomal Dominant
  • Autosomal Recessive
  • Avascular Necrosis of Femoral head
  • Axillary Nerve
  • Azathioprine 💊
  • Azithromycin 💊
  • B lymphocytes
  • BRASH syndrome
  • BRCA genes (Familial Breast Cancer)
  • Bacillary Dysentery
  • Bacillus cereus poisoning
  • Back pain ✅
  • Backpain / Backache
  • Baclofen 💊
  • Bacteria and their Infections
  • Bacterial Vaginosis
  • Bacteroides fragilis
  • Baker's (Popliteal) Cyst
  • Balanitis (Adults)
  • Balanitis (Children)
  • Balkan endemic nephropathy (BEN)
  • Balsalazide (Aminosalicylate) 💊
  • Barrett's oesophagus ✅
  • Barthel Index
  • Bartonella
  • Bartonella henselae (Cat Scratch Disease)
  • Bartters syndrome
  • Basal Cell Carcinoma (BCC) ✅
  • Basic Chemistry for Medicine
  • Basic Concepts of Pregnancy
  • Basic Neuroscience
  • Basic Neuroscience
  • Basic Physics for Medicine
  • Basic Statistics
  • Basics of Endocrinology
  • Basilar artery thrombosis
  • Bayes' Theorem
  • Becker Muscular dystrophy
  • Beclometasone (Beclomethasone) 💊
  • Beer Potomania
  • Behaviour/personality change ✅
  • Behavioural and Psychological (BPSD) Symptoms of Dementia
  • Behavioural difficulties in Adults ✅
  • Behavioural difficulties in childhood
  • Behcet's Syndrome
  • Bejel ( Treponema pallidum subspecies endemicum)
  • Belantamab mafodotin (Blenrep)
  • Bell's Palsy (Facial nerve palsy)
  • Bendroflumethiazide (Bendrofluazide) 💊
  • Benign Breast Disease
  • Benign Eyelid Conditions
  • Benign Paroxysmal Positional Vertigo (BPPV)
  • Benign Prostatic Hyperplasia✅
  • Benign recurrent intrahepatic cholestasis
  • Benzodiazepine Toxicity
  • Benzodiazepines
  • Benzylpenicillin Sodium (Penicillin G) 💊
  • Berg Balance Scale
  • Beriplex 💊
  • Berylliosis
  • Beta Agonists 💊
  • Beta Antagonists/Blockers
  • Beta Blocker toxicity⚠️
  • Beta Thalassaemia ✅
  • Beta-2 Microglobulin
  • Beta-lactamases 💊
  • Betahistine (Serc) 💊
  • Bezafibrate 💊
  • Bezafibrate 💊
  • Biceps tendon rupture
  • Bilateral Pontine Infarction due to Basilar Artery Thrombosis
  • Bile salt malabsorption (BAM)
  • Biliary atresia
  • Bilirubin
  • Biochemical Lab values
  • Biochemistry and Physiology of Globins
  • Biological Agents
  • Bioterrorism
  • Bipolar disorder: mania and hypomania ✅
  • Birt-Hogg-Dubé Syndrome
  • Bisacodyl 💊
  • Bisoprolol 💊
  • Bisphosphonates 💊
  • Bites and stings
  • Blackouts and faints (TLOC)
  • Bladder Cancer
  • Bladder Stones
  • Blank Templates
  • Bleeding Antepartum
  • Bleeding or High INR on Warfarin or other Anticoagulation
  • Bleomycin
  • Blindness - global causes
  • Blood
  • Blood Pressure
  • Blood Transfusion Reactions
  • Blood cultures
  • Blood film interpretation
  • Blood transfusion
  • Blotting Techniques: Gel Electrophoresis
  • Body Mass Index
  • Bone Pain
  • Bone Physiology
  • Bone disease Lab results
  • Bone metabolism RANK RANKL OPG pathway
  • Bone scintigraphy (Bone scan)
  • Bordetella pertussis (Whooping cough)
  • Borrelia burgdorferi
  • Borrelia recurrentis
  • Bortezomib
  • Botulism
  • Boxer's fracture
  • Brachial neuritis (neuralgic amyotrophy) Parsonage-Turner syndrome
  • Brain Abscess
  • Brain CT Collection
  • Brain Embryology
  • Brain Herniation syndromes
  • Brain MRI
  • Brain MRI Collection
  • Brain Metastases
  • Brain Natriuretic Peptide (BNP)
  • Brain Tumours in Children
  • Brain Tumours ✅
  • Branchial cleft cyst
  • Breaking Bad News (OSCE)
  • Breast Cancer ✅
  • Breast Cysts
  • Breast Lump Evaluation
  • Breast abscess and Mastitis and Fat Necrosis
  • Breast tenderness/pain
  • Breathlessness
  • Bretylium 💊
  • Brighton Mobility Score
  • Broad Complex Tachycardia
  • Bromocriptine 💊
  • Bronchial adenoma
  • Bronchiectasis
  • Bronchiolitis
  • Bronchoscopy
  • Brown-Sequard Spinal Cord syndrome
  • Brucella
  • Brucellosis
  • Brugada syndrome ✅
  • Bruising
  • Budd-Chiari syndrome ✅
  • Budesonide 💊
  • Buerger disease (Thromboangiitis obliterans) ✅
  • Bulbar vs Pseudobulbar palsy
  • Bulimia Nervosa
  • Bullous Pemphigoid ✅
  • Bumetanide
  • Bunions
  • Buprenorphine 💊
  • Bupropion 💊
  • Burkholderia cepacia
  • Burkitt's lymphoma
  • Burns Management Guide
  • Busulphan (Busulfan)
  • Byssinosis
  • C Programming
  • C# programming
  • C++ Programming
  • CADASIL
  • CARASIL
  • CNS fungal Infections
  • CNS infections
  • CSF Interpretation
  • CSF Rhinorrhoea
  • CT Basics for Stroke
  • CT Pulmonary angiogram (CTPA)
  • Cabergoline
  • Caesarean Section (CS)
  • Café-au-lait spots
  • Caisson Disease Decompression sickness (The Bends)
  • Calcific Uraemic Arteriolopathy (Calciphyalxis)
  • Calcitonin
  • Calcitriol (1,25 Dihydroxycholecalciferol) 💊
  • Calcium Channel Blockers
  • Calcium Chloride or Gluconate
  • Calcium Physiology
  • Calcium Pyrophosphate Deposition (Pseudogout)
  • Calcium Resonium
  • Calcium channel blockers toxicity⚠️
  • Calot's triangle
  • Campylobacter jejuni
  • Canaliculitis 👁️
  • Cancer Pathology
  • Cancer and Stroke
  • Cancer of Unknown Primary
  • Candesartan 💊
  • Candida Skin Infections ✅
  • Candidiasis
  • Cannabinoid Hyperemesis Syndrome (CHS)
  • Cannabis toxicity⚠️
  • Cannonball Metastases
  • Capacity in Older Adult
  • Capecitabine 💊
  • Caplacizumab 💊
  • Capnocytophaga canimorsus
  • Capnography
  • Capreomycin
  • Capsular and Pontine Warning Syndromes
  • Captopri 💊
  • Carbamazepine 💊
  • Carbapenemase-producing Enterobacteriaceae
  • Carbimazole 💊
  • Carbohydrates
  • Carbon Monoxide Toxicity
  • Carbon Tetrachloride Toxicity
  • Carbon dioxide embolism
  • Carcinoembryonic antigen (CEA)
  • Carcinoid Heart Disease ❤️
  • Carcinoid Tumour Syndrome
  • Carcinoma of the Bile Duct
  • Carcinoma of the Gallbladder ✅
  • Cardiac Amyloid heart disease
  • Cardiac Arrest in Pregnancy
  • Cardiac Catheter ablation
  • Cardiac Crib Sheets
  • Cardiac Echocardiography: Basics and Uses
  • Cardiac Electrophysiology and Arrhythmia management
  • Cardiac Embryology
  • Cardiac MRI ❤️
  • Cardiac Resynchronisation Therapy (CRT) Pacemaker
  • Cardiac Syndrome X (Microvascular Angina)
  • Cardiac Troponins
  • Cardiac Troponins
  • Cardiac and Respiratory Rehabilitation
  • Cardioembolic stroke
  • Cardiogenic shock
  • Cardiological Emergencies: Revision ✅
  • Cardiology Examination (OSCE)
  • Cardiology Investigations
  • Cardiology Revision Guide ✅
  • Cardiology: Cardiology Emergencies
  • Cardiology: Anatomy Physiology and Pharmacology
  • Cardiology: Heart Failure (Complete) ✅
  • Cardiology: History and Examination
  • Cardiology: Infective Endocardits
  • Cardiology: Ischaemic Heart Disease (ACS)
  • Cardiology: Pericardial Disease
  • Cardiology: Valvular heart disease
  • Cardiology: Venous Thromboembolism and Pulmonary Vascular Disease
  • Cardiology:Cardiac Arrhythmias
  • Cardiology:Cardiomyopathies
  • Cardiology:Congenital heart disease
  • Cardiology:Heart Failure
  • Cardiology:Hypertension, Blood Pressure and Prevention
  • Cardiopulmonary bypass
  • Cardiorenal Syndromes ✅
  • Cardiorespiratory Arrest
  • Caring for Patients with Dementia
  • Carmustine 💊
  • Caroticocavernous Fistula
  • Carotid Artery Dissection
  • Carotid Body Tumour
  • Carotid Endarterectomy ✅
  • Carotid Sinus Syncope
  • Carotid Web
  • Carotid sinus massage
  • Carpal tunnel syndrome
  • Carvedilol 💊
  • Caspases
  • Castleman's disease
  • Cataract
  • Catheter Related UTI
  • Catheter related Blood stream infection
  • Cauda Equina Syndrome (CES)
  • Caudate Nucleus
  • Causes of Eosinophila
  • Causes of Fatigue
  • Causes of Gradual Visual Loss over weeks and months
  • Causes of Ketoacidosis
  • Causes of Limp in Children
  • Causes of Neck Pain/Stiffness
  • Causes of Precious Puberty in Children
  • Causes of Ptosis
  • Causes of Short Stature in Children
  • Causes of Stroke
  • Causes of Tall Stature in Children
  • Causes of Tremor
  • Causes of Vertigo
  • Causes of a high Erythrocyte Sedimentation rate (ESR)
  • Causes of abnormal Vaginal bleeding
  • Causes of delayed Onset of Puberty in Children ✅
  • Causes of high C reactive protein (CRP)
  • Cavernous angiomas (Cavernomas)
  • Cavernous sinus
  • Cavernous sinus thrombosis
  • Cefaclor 💊
  • Cefalexin 💊
  • Cefotaxime 💊
  • Ceftazidime 💊
  • Ceftriaxone 💊
  • Cefuroxime 💊
  • Celecoxib 💊
  • Cell Adhesion Molecules
  • Cell Biology
  • Cell Cycle
  • Cell Response to Injury
  • Cellulitis and Erysipelas ✅
  • Central Pontine Myelinolysis (Osmotic Demyelination Syndrome) ✅
  • Central Retinal Arterial Occlusion (CRAO)
  • Central Spinal Cord Syndrome
  • Central Venous line Insertion
  • Central and Branch Retinal Vein Occlusion (CRVO/BRVO)
  • Centronuclear Myopathy (CNM)
  • Cerebellar Examination (OSCE)
  • Cerebellar Haemorrhage
  • Cerebellar Ischaemic Stroke
  • Cerebral Amyloid angiopathy (CAA) ✅
  • Cerebral Angiitis
  • Cerebral Angiography
  • Cerebral Angiography and Perfusion
  • Cerebral Arterial Perfusion and Clinical Correlates
  • Cerebral Atrophy vs Hydrocephalus
  • Cerebral Cortex
  • Cerebral Palsy & HIE
  • Cerebral Radiation Vasculopathy
  • Cerebral Salt Wasting
  • Cerebral Vasculitis
  • Cerebral Veins 🧠
  • Cerebral Venous Thrombosis (CVT)
  • Cerebral arteritis
  • Cerebral microbleeds
  • Cervical Cancer screening
  • Cervical Lymphadenopathy
  • Cervical Smear Results ✅
  • Cervical Spine Immobilisation and Management
  • Cervical cancer
  • Cervical screening (HPV)
  • Cervical spondylosis
  • Cetirizine 💊
  • Chalazion
  • Chancroid
  • Change in Bowel habit
  • Change in stool colour
  • Charcot Foot Syndrome (CFS)
  • Charcot Marie Tooth (CMT) disease
  • Chediak Higashi syndrome
  • Chemical Pathology
  • Chemosis
  • Chemotherapeutic Agents
  • Chest Abdomen anatomy
  • Chest Pain
  • Chest Pain in the Emergency Department (OSCE focused) ❤️
  • Chest X Ray Collection
  • Chest X Ray Interpretation
  • Chest drain Insertion (Thoracostomy)
  • Chickenpox Varicella Infection ✅
  • Child Abuse and Safeguarding NHS
  • Child abuse
  • Child-Pugh Score: Child-Pugh Score: Cirrhosis Severity
  • Childhood Vaccination in the UK
  • Childhood Vaccination in the USA
  • Chlamydia Infections
  • Chlamydia psittaci
  • Chlamydia trachomatis
  • Chlamydophila pneumoniae
  • Chlorambucil
  • Chloramphenicol 💊
  • Chlordiazepoxide 💊
  • Chloroquine 💊
  • Chlorphenamine(Chlorpheniramine) 💊
  • Chlorpromazine 💊
  • Cholangiocarcinoma
  • Cholera (Vibrio cholera)
  • Cholestatic Jaundice
  • Cholesteatoma
  • Cholesterol - Lipids
  • Cholesterol Embolisation Syndrome
  • Cholinergic crisis-syndrome
  • Chondrocalcinosis
  • Chorea - Ballismus
  • Choreoacanthocytosis
  • Chorioamnionitis
  • Choriocarcinoma - Malignant Gestational Trophoblastic Disease
  • Chromatin
  • Chronic Bronchitis
  • Chronic Fatigue Syndrome 🧠
  • Chronic Glaucoma
  • Chronic Granulomatous Disease
  • Chronic Hepatitis
  • Chronic Inflammation
  • Chronic Inflammatory Demyelinating polyneuropathy
  • Chronic Interstitial Nephritis
  • Chronic Kidney Disease (CKD) ✅
  • Chronic Liver Disease ✅
  • Chronic Lymphocytic leukaemia (CLL) ✅
  • Chronic Myeloid Leukaemia (CML) ✅
  • Chronic Obstructive Pulmonary Disease (COPD) ✅
  • Chronic Pancreatitis ✅
  • Chronic Peritonitis
  • Chronic Radiation Enteritis
  • Chronic Rash (Adult/Child)
  • Chronic Urinary Retention
  • Chronic Vision Uni-Bilateral loss (Blindness)
  • Chronic Visual Loss (OSCE focused)
  • Chronic abdominal pain
  • Chronic and recurrent Meningitis
  • Chronic joint pain/stiffness 🦴
  • Chronic mucocutaneous candidiasis
  • Ciclosporin 💊
  • Cimetidine 💊
  • Cinacalcet
  • Ciprofloxacin 💊
  • Circulatory Shock (Volume loss)
  • Cirrhosis
  • Cisatracurium
  • Cisplatin
  • Citalopram 💊
  • Cladribine
  • Clarithromycin 💊
  • Cleft lip or palate
  • Clindamycin 💊
  • Clinical Appearance Collections
  • Clinical Genetics Revision Guide ✅
  • Clinical History Pleuritic Chest Pain 🩺
  • Clinical Immunology #1
  • Clinical Immunology #2
  • Clinical Immunology #3
  • Clinical imaging #1
  • Clinical imaging #2
  • Clinical imaging #3
  • Clinical pharmacology and prescribing #1
  • Clinical pharmacology and prescribing #2
  • Clinically Isolated Syndrome (CIS) – First Demyelinating Event
  • Clonidine 💊
  • Clopidogrel 💊
  • Clostridioides difficile Infection
  • Clostridium botulinum Infection
  • Clostridium perfringens
  • Clostridium tetani - Tetanus
  • Clotrimazole cream 💊
  • Clotting pathways
  • Clozapine 💊
  • Clustered Regularly Interspaced Short Palindromic Repeats CRISPR
  • Co Careldopa (Sinemet)
  • Co-Beneldopa (Madopar)
  • Co-codamol 💊
  • Co-trimoxazole (Trimethoprim + Sulfamethoxazole) 💊
  • CoAmoxiclav (Augmentin) 💊
  • Coagulopathy
  • Coal Worker's Pneumoconiosis
  • Coarctation of the Aorta ✅
  • Cobalt Cardiomyopathy
  • Cocaine Toxicity and Chest pain
  • Cocaine abuse
  • Cocaine toxicity⚠️
  • Coccidioidomycosis
  • Codeine 💊
  • Coding
  • Coeliac disease ✅
  • Cogan Syndrome
  • Colchicine 💊
  • Cold Agglutinin Disease (CAD/AIHA)
  • Collagen
  • Colles’ fracture of the Radius
  • Colloid cyst in the third ventricle
  • Colloids vs Crystalloids
  • Coloboma
  • Colonic (Large bowel) Obstruction
  • Colonoscopy
  • Colorectal polyps ✅
  • Colorectal tumours ✅
  • Colposcopy
  • Comatose Patient (OSCE focused)
  • Combined Oral contraceptive pill (COCP) 💊
  • Common Chromosomal Defects
  • Common Genetic Disorders
  • Common Peroneal Nerve (CPN)
  • Common Problems in Elderly
  • Common Psychiatric Emergencies: Revision ✅
  • Common variable immunodeficiency
  • Commotio cordis
  • Community Acquired Pneumonia 🫁 ✅
  • Comparing Groups
  • Compilers
  • Complement
  • Components of a Eukaryotic Gene
  • Comprehensive Clinical Microbiology Tutorial for Medical Students
  • Comprehensive Geriatric Assessment (CGA)
  • Computer Networking
  • Computer Security
  • Concurrent Programming
  • Confirming Death
  • Confusion (OSCE focused)
  • Congenital Acyanotic Heart Disease
  • Congenital Adrenal hyperplasia
  • Congenital Complete Heart Block
  • Congenital Cyanotic Heart Disease (Children)
  • Congenital Hypothyroidism
  • Congenital Talipes Equinovarus - Clubfoot
  • Congenital abnormalities
  • Conjunctivitis
  • Consent ✅
  • Constipation (Adults) ✅
  • Constipation (Children)
  • Constipation in the Elderly
  • Constrictive Pericarditis ❤️
  • Contact Dermatitis
  • Continuous Ambulatory Peritoneal Dialysis (CAPD)
  • Continuous Positive Airways Pressure (CPAP) ✅
  • Contraception request/advice ✅
  • Conus Medullaris syndrome
  • Cor Pulmonale
  • Cord Prolapse
  • Corneal Abrasion
  • Coronary artery bypass graft surgery ✅
  • Coronavirus SARS-CoV-2 (COVID-19) ✅
  • Corticobasal degeneration (Dementia)
  • Corticospinal Tract
  • Corticosteroid-related psychosis 💊
  • Corticosteroids : Uses and Cautions
  • Cotard's Syndrome
  • Cough (Adult)
  • Cough (Child)
  • Cowden Syndrome / PTEN Hamartoma Tumour Syndrome
  • Cowpox (Orthopoxvirus)
  • Coxiella Burnetii Q fever
  • Cramps
  • Craniopharyngioma
  • Creatinine Clearance
  • Creutzfeldt Jakob disease
  • Cri du Chat Syndrome
  • Crimean-Congo haemorrhagic fever
  • Critical Illness Neuromuscular Weakness (CINMW)
  • Critical care Crib Sheets
  • Crohn's disease ✅
  • Croup
  • Crouzon Syndrome
  • Crying baby 👶
  • Cryoprecipitate
  • Cryptococcus neoformans infections (Cryptococcal Infections)
  • Cryptogenic Organising Pneumonia (COP-BOOP)
  • Cryptogenic stroke
  • Cryptography
  • Cryptosporidiosis ✅
  • Crystal arthropathy
  • Cushing disease
  • Cushing syndrome
  • Cushing's Syndrome due to Ectopic ACTH
  • Cutaneous Larva Migrans
  • Cutaneous Warts
  • Cutaneous fungal infections
  • Cyanide toxicity⚠️
  • Cyanosis ❤️
  • Cyclical Vomiting Syndrome
  • Cyclizine
  • Cyclo-oxygenase (COX) enzymes
  • Cyclophosphamide 💊
  • Cycloserine
  • Cys leukotriene receptor antagonists 💊
  • Cystic Fibrosis ✅
  • Cystinosis
  • Cystinuria
  • Cystitis and Urethritis (UTI)
  • Cystoscopy
  • Cytokine Physiology
  • Cytomegalovirus (CMV) Retinitis ✅
  • Cytomegalovirus (CMV) infections
  • D Dimer
  • D-lactic acidosis or D-lactate encephalopathy
  • DNA and RNA
  • DNA replication
  • DNACPR in the Older Person
  • Dabigatran 💊
  • Dalteparin 💊
  • Dandy Walker syndrome
  • Dantrolene 💊
  • Dapagliflozin 💊
  • Darier’s disease (Keratosis Follicularis)
  • Darunavir 💊
  • Data Security and Protection
  • Data Structures
  • Data security awareness
  • Database Management
  • DeQuervain's thyroiditis
  • Death Certificates and Cremation UK
  • Death and dying
  • Decision Making by Clinicians
  • Decompressive Hemicraniectomy
  • Decreased appetite
  • Deep Vein Thrombosis (DVT) ✅
  • Deep brain stimulation
  • Dehydration (Child)
  • Dehydration Adult
  • Delusions
  • Demeclocycline 💊
  • Dementia with Lewy bodies
  • Dementias ✅
  • Demyelinating Diseases
  • Dengue Fever
  • Denosumab (Prolia) 💊
  • Dental Caries
  • Dentatorubral Pallidoluysian Atrophy (DRPLA)
  • Deprivation of Liberty Safeguards (DoLS) ✅
  • Dermatitis Herpetiformis
  • Dermatology Emergencies ✅
  • Dermatology Revision Guide ✅
  • Dermatology terms
  • Dermatology: Skin basics, eczema and psoriasis
  • Dermatology: Skin infections and infestations
  • Dermatology: Skin lesions and skin cancer
  • Dermatology: Urticaria, drug reactions, blistering, ulcers and emergencies
  • Dermatomes
  • Dermatomyositis ✅
  • Dermoid cysts
  • Desferrioxamine 💊
  • Desmopressin (DDAVP) 💊
  • Desogestrel (Progestogen Only Pill) 💊
  • Developmental Delay & Abnormal Development in Children
  • Developmental Dislocation (Dysplasia) of the Hip (DDH)
  • Dexamethasone 💊
  • DiGeorge syndrome (22q11.2 deletion syndrome)
  • Diabetes Crib Sheets
  • Diabetes Insipidus (AVP Deficiency)
  • Diabetes Mellitus Type 1 and DKA (children)
  • Diabetes Mellitus Type 1 ✅
  • Diabetes Mellitus Type 2 ✅
  • Diabetes Mellitus Type 3C
  • Diabetes Variable Rate Insulin Infusion
  • Diabetes and Hypertension
  • Diabetes and Pregnancy
  • Diabetes in Children
  • Diabetes: (Autonomic) Neuropathy (DAN)
  • Diabetes: Basics ✅
  • Diabetes: Complications
  • Diabetes: Criteria US and UK
  • Diabetes: Eye Disease
  • Diabetes: Foot Problems
  • Diabetic Amyotrophy ✅
  • Diabetic Eye Disease
  • Diabetic Ketoacidosis (DKA) Adults ✅
  • Diabetic Ketoacidosis (DKA) Children
  • Diabetic nephropathy
  • Diabetic neuropathy
  • Diamond-Blackfan anaemia
  • Diamorphine 💊
  • Diaphragmatic disorders
  • Diarrhoea (Children)
  • Diazepam 💊
  • Didanosine (ddI) 💊
  • Diethylstilbestrol
  • Dieulafoy Lesion
  • Different Forms of Medical Trials and Studies
  • Differential Diagnosis of Malar Rash
  • Differentials of ABC
  • Differentials of Painful thigh
  • Differentiation syndrome
  • Difficulty Swallowing (Dysphagia)
  • Difficulty with breastfeeding
  • Diffuse Alveolar Haemorrhage (DAH)
  • Diffuse Oesophageal spasm
  • Diffuse Parenchymal Lung Disease (DPLD) or Interstitial Lung Disease (ILD)
  • Diffuse large B-cell lymphoma
  • Diffusion Capacity
  • Digoxin Toxicity⚠️
  • Digoxin 💊
  • Digoxin-specific antibody ✅
  • Dihydrocodeine 💊
  • Dilated Cardiomyopathy ✅
  • Diltiazem 💊
  • Diphtheria (Corynebacterium diphtheriae)
  • Diplopia (Double Vision)
  • Dipyridamole 💊
  • Discharges against advice
  • Discoid lupus erythematosus (DLE)
  • Disease prevention/screening
  • Diseases with associated cancers
  • Dislocation Sternoclaivcular joint
  • Disopyramide 💊
  • Disseminated Intravascular Coagulation (DIC)
  • Distal Humerus Fracture
  • Distal Radius Fracture
  • Distributive Shock (Reduced SVR vasodilated)
  • Disulfiram (Antabuse) 💊
  • Diuretics
  • Diverticular disease and Acute Diverticulitis ✅
  • Diving Physiology
  • Dizziness
  • Dobutamine 💊
  • Dog Bites ✅
  • Domestic Violence and Safeguarding NHS
  • Domperidone 💊
  • Donepezil (Aricept) 💊
  • Donovanosis
  • Dopamine Hydrochloride 💊
  • Dopamine agonists 💊
  • Dornase Alpha ✅
  • Dosing Gentamicin
  • Downs syndrome
  • Doxapram 💊
  • Doxazosin (Cardura) 💊
  • Doxepin 💊
  • Doxorubicin (Adriamycin)
  • Doxycycline 💊
  • Driving Advice
  • Drowning ✅
  • Drug Induced Parkinson disease
  • Drug Metabolism
  • Drug Overdose Adults
  • Drug Reaction Eosinophilia Systemic Symptoms (DRESS syndrome)
  • Drug Toxicity Assessment and Management ⚠️
  • Drug induced Lupus Erythematosus
  • Drug induced liver disease
  • Drug overdose children ✅
  • Drugs
  • Drugs to Avoid in Acute Renal failure
  • Drugs to avoid in Liver failure
  • Dry and Wet and Gas Gangrene
  • Dual X-ray absorptiometry (DEXA)
  • Duchenne Muscular Dystrophy
  • Duke’s Criteria for Infective Endocarditis ✅
  • Dulaglutide GLP-1 agonist 💊
  • Duloxetine 💊
  • Duodenal Atresia (Children)
  • Dupuytrens contracture ✅
  • Dural Arteriovenous Malformations
  • Dysmorphic child
  • Dyspepsia (OSCE focused)
  • Dysphagia / Swallowing Problems ✅
  • ECG - Acute Coronary Syndrome ❤️
  • ECG - Artefact
  • ECG - Asystole and P wave Asystole
  • ECG - Bundle Branch Blocks
  • ECG - Calculate the electrical axis
  • ECG - Causes of a Dominant R wave in V1 ❤️
  • ECG - Collection A
  • ECG - Collection B
  • ECG - Heart Block
  • ECG - Hyperkalaemia ❤️
  • ECG - Left Axis Deviation
  • ECG - Left Bundle Branch Block LBBB
  • ECG - Left Ventricular Hypertrophy
  • ECG - Low Voltage Complexes
  • ECG - NSTEMI
  • ECG - Normal 12 Lead
  • ECG - P wave
  • ECG - Pathological Q waves
  • ECG - Potential Errors
  • ECG - QT interval ❤️
  • ECG - Right Axis Deviation
  • ECG - Right Bundle Branch Block RBBB
  • ECG - Right Ventricular Hypertrophy
  • ECG - ST segment changes
  • ECG - ST-T T waves changes
  • ECG - STEMI
  • ECG - Sinoatrial block ❤️
  • ECG - Sinus Bradycardia
  • ECG - The QRS complex
  • ECG - short PR interval
  • ECG Analysis
  • ECG Reading & Interpretation MLA and Exams 🫀
  • ECG/EKG Crib sheets
  • EEG (Electroencephalogram)
  • ENT Emergencies: Revision ✅
  • ENT infections
  • ENT: Common Ear disorders
  • ENT: Common Nose and Throat disorders
  • ENT: Emergenices
  • ENT: Neck lumps and cancer
  • Ear Pain (Otalgia)
  • Ear and Nasal Discharge
  • Eating Disorders
  • Ebola Virus Disease ✅
  • Ebstein anomaly ❤️
  • Echinocytes
  • Ecstasy toxicity⚠️
  • Ectopia lentis (subluxation of the lens)
  • Ectopic Pregnancy
  • Ectropion
  • Eculizumab 💊
  • Eczema/Dermatitis
  • Edoxaban (Lixiana)
  • Edward syndrome (trisomy 18 syndrome)
  • Efavirenz (Sustiva) EFV 💊
  • Ehlers-Danlos syndromes
  • Ehrlichiosis
  • Eikenella corrodens
  • Eisenmenger's syndrome ❤️
  • Elation/elated mood
  • Elbow Dislocation
  • Elder Abuse and Safeguarding
  • Elderly Medicine / Geriatrics Revision Guide ✅
  • Electrical Storm (Recurrent VT/VF)
  • Electrical injury
  • Electrolyte Abnormalities
  • Electron Transport Chain
  • Embryology of Blood and Immune System
  • Embryology of Limb Development
  • Embryology of Nervous system
  • Embryology of Organ Development
  • Emergency Drugs Collection
  • Emergency Medicine Revision Guide✅
  • Emphysema
  • Empty sella syndrome
  • Emtricitabine (Emtriva) FTC 💊
  • Enalapril 💊
  • Encephalocoele
  • Encopresis in Children ✅
  • End of Life Care Prescribing ✅
  • End of Life care in Diabetes
  • End of life care in Head & Neck cancer
  • Endocrine Emergencies: Revision ✅
  • Endocrine: Anatomy Physiology and Pharmacology
  • Endocrinology Revision Guide ✅
  • Endocrinology: Adrenal Disease
  • Endocrinology: Diabetes
  • Endocrinology: Lipids and obesity
  • Endocrinology: NETS and Hypoglycaemia
  • Endocrinology: Pituitary Disease
  • Endocrinology: Reproductive
  • Endocrinology: Sodium and Water disorders
  • Endocrinology: Thyroid disease
  • Endocrinology:: Emergencies
  • Endocrinology::Bone Medicine
  • Endometrial (Uterine) Cancer
  • Endometriosis
  • Endophthalmitis ✅
  • Endoscopic Retrograde Cholangiopancreatography (ERCP)
  • Endothelins
  • Enfuvirtide 💊
  • Enoxaparin Sodium (Clexane-Lovenox) 💊
  • Enoximone 💊
  • Entacapone
  • Enteric Fever (Typhoid/Paratyphoid) ✅
  • Enterococci
  • Enteropathic Spondyloarthritis
  • Entropion
  • Enuresis/Bedwetting in Children ✅
  • Enzyme inducers and inhibitors
  • Enzymes in Humans
  • Eosinophilic Oesophagitis
  • Eosinophilic granulomatosis (Churg Strauss)
  • Ependymoma
  • Epididymitis and Orchitis (Children)✅
  • Epididymitis and Orchitis in Adults
  • Epidural Haematoma
  • Epidural Spinal abscess
  • Epilepsy - Diagnosis
  • Epilepsy - Idiopathic Generalised Epilepsy
  • Epilepsy in Pregnancy
  • Epilepsy ✅
  • Episcleritis
  • Epistaxis
  • Eplerenone 💊
  • Eponymous brainstem strokes
  • Epstein-Barr Virus infection
  • Equality Diversity and Human Rights
  • Equality Diversity and Inclusion
  • Erb Palsy
  • Erectile dysfunction
  • Ergocalciferol (Calciferol) 💊
  • Erlotinib (Tarceva) 💊
  • Erysipelas ✅
  • Erysipelothrix rhusiopathiae
  • Erythema Gyratum Repens
  • Erythema Multiforme ✅
  • Erythema Nodosum
  • Erythema ab Igne
  • Erythrocytes / Red Blood Cells 🩸
  • Erythrodermic Psoriasis
  • Erythromycin 💊
  • Escherichia coli (E. coli)
  • Escitalopram 💊
  • Esomeprazole 💊
  • Essential Hypertension ✅
  • Essential Thrombocythaemia (ET) ✅
  • Essential Tremor
  • Etanercept 💊
  • Ethambutol 💊
  • Ethanol toxicity⚠️
  • Ethanol 💊
  • Ethylene glycol toxicity
  • Etomidate
  • Etravirine (intelence) ETR 💊
  • Euglycaemic Ketoacidosis (euDKA) with SGLT2 Inhibitors
  • Ewing sarcoma
  • Exchange Transfusion
  • Exenatide (Byetta) GLP1 agonist 💊
  • Exercise Physiology
  • Exercise stress test
  • Exploding head syndrome
  • Extradural haemorrhage
  • Extramedullary plasmacytoma
  • Extrapyramidal symptoms
  • Extrinsic Allergic alveolitis (Hypersensitivity Pneumonitis)
  • Eye Collection
  • Eye Trauma
  • Eye infections
  • Eye pain/discomfort
  • Ezetimibe 💊
  • FDG PET/CT Scans
  • Fabry disease
  • Facial Nerve (VII Cranial nerve)
  • Facial and Periorbital Swelling
  • Facial pain
  • Facioscapulohumeral muscular dystrophy
  • Factor V Leiden Deficiency
  • Faecal Calprotectin
  • Faecal Incontinence
  • Failure to thrive or Faltering growth
  • Falls
  • Familial Adenomatous polyposis (FAP) ✅
  • Familial Hyperlipidaemias
  • Familial Mediterranean Fever (FMF) ✅
  • Familial hypocalciuric hypercalcaemia (FHH)
  • Familial/Hereditary Amyloidosis
  • Family Tree (Pedigree)
  • Family history of possible genetic disorder
  • Famotidine 💊
  • Famous Medical Triads
  • Fanconi Anaemia
  • Fanconi Syndrome
  • Farmer's lung
  • Fasciculation
  • Fast Atrial Fibrillation and Rate Control
  • Fat Metabolism
  • Fat embolism ✅
  • Fatal Familial Insomnia (FFI)
  • Fatty acids
  • Febrile convulsion
  • Felodipine (Dihydropyridine)
  • Femoral Hernia
  • Femoral Shaft Fractures
  • Femoral Vein Cannulation
  • Femoral nerve
  • Fentanyl - Fentanil
  • Ferritin
  • Ferrous Fumarate - Gluconate - Sulphate 💊
  • Fertilisation and Formation of Zygote
  • Fetal Alcohol Syndrome
  • Fetal-type Posterior cerebral artery (FTP)
  • Fever - all ages
  • Fever Pyrexia of unknown origin (FUO PUO)
  • Fever in IV Drug User (PUO)
  • Fever in a traveller
  • Fibrinogen
  • Fibromuscular Dysplasia ✅
  • Fibromyalgia ✅
  • Fibrotic Lung Disease
  • Fidaxomicin 💊
  • Fifth Disease (Erythrovirus B19 infection)
  • Finasteride (5 alpha-reductase inhibitor) 💊
  • Fire Safety for NHS Professionals
  • First Seizure
  • First Seizure (OSCE focused)
  • Fissure in Ano
  • Fistulo in Ano
  • Fit Notes in General Practice (UK)
  • Fits/seizures and Epilepsy (Children)
  • Fitz-Hugh Curtis Syndrome
  • Fixed Abnormal Beliefs (Delusions)
  • Flashes and Floaters in the Visual Field
  • Flecainide Acetate 💊
  • Flexor sheath infection (flexor tenosynovitis)
  • Flow Cytometry
  • Flucloxacillin 💊
  • Fluconazole 💊
  • Flucytosine 💊
  • Fludrocortisone 💊
  • Fluid balance status and management
  • Flumazenil (Annexate - Romazicon) 💊
  • Fluoxetine 💊
  • Focal Cortical Dysplasia (FCD)
  • Focal Segmental Glomerulosclerosis (FSGS)
  • Foix-Alajouanine syndrome
  • Folate (Folic) acid (B9) 💊
  • Folate deficiency (B9) ✅
  • Folinic acid (Leucovorin) 💊
  • Follicular lymphoma
  • Folliculitis
  • Fomepizole 💊
  • Fondaparinux 💊
  • Food Intolerance in Children
  • Food borne disease
  • Foot Drop
  • Forearm Fractures
  • Foreign Body in Eye
  • Foscarnet Sodium 💊
  • Fosfomycin
  • Foslevodopa / Foscarbidopa
  • Fosphenytoin 💊
  • Foster Kennedy Syndrome
  • Fourniers gangrene
  • Fractured Clavicle
  • Fractured Neck of Femur/Femoral Neck
  • Fractured Pubic Ramus
  • Fractured Scapula
  • Fractured Shaft Femur
  • Fractured Tibia and Fibula
  • Fractures in Children
  • Fractures of the Upper humerus
  • Fragile X syndrome
  • Frailty an Overview
  • Fraser guidelines and Gillick Competence
  • Free Radicals
  • Fresh Frozen Plasma
  • Friedreichs Ataxia
  • Frontotemporal dementia
  • Full or Complete Blood Count (FBC CBC)
  • Functional organization of a eukaryotic gene
  • Fungi and their infections
  • Furosemide (Frusemide)
  • Fusidic acid 💊
  • Fusobacteria - Tropical ulcer
  • Fusobacterium
  • G protein-coupled receptors
  • GLP-1 Receptor Agonists
  • Gabapentin 💊
  • Galactorrhoea
  • Galactosaemia
  • Galantamine
  • Gallstone ileus
  • Gallstones and biliary colic
  • Gamete intra-fallopian tube transfer (GIFT)
  • Gametogenesis
  • Gamma Glutamyl Transferase (GGT)
  • Gamma hydroxy butyrate (GHB) toxicity⚠️
  • Ganciclovir - Valganciclovir 💊
  • Ganglion Cysts
  • Gardner's syndrome
  • Gardnerella vaginalis
  • Gas Gangrene (Clostridial Myonecrosis)
  • Gastric (MALT) Lymphoma
  • Gastric Cancer ✅
  • Gastric Outlet obstruction (pyloric stenosis) in Adults ✅
  • Gastrinoma
  • Gastro Intestinal Stromal Tumours (GIST)
  • Gastro-Oesophageal Reflux (GORD/GERD) ✅
  • Gastro-Oesophageal Reflux (Paediatrics GORD) ✅
  • Gastro-oesophageal reflux in Children ✅
  • Gastroenteritis in Adults ✅
  • Gastroenteritis in Children
  • Gastroenterology Examination
  • Gastroenterology Examination (OSCE)
  • Gastroenterology Revision Article ✅
  • Gastroenterology: Anatomy Physiology Pharmacology
  • Gastroenterology: Bowel Disorders
  • Gastroenterology: Cirrhosis and Transplantation
  • Gastroenterology: Gastroenterology Emergencies (Complete)
  • Gastroenterology: Inflammatory Bowel Disease
  • Gastroenterology: Investigations
  • Gastroenterology: Liver disease
  • Gastroenterology: Oesophagus and Stomach
  • Gastroenterology: Pancreas and Biliary
  • Gastrointestinal Emergencies:Revision✅
  • Gastrostomy (PEG) tube managment
  • Gaucher's disease
  • Gene components
  • General Anaesthesia (GA) 💤
  • General Basic Fracture management ✅
  • Genetic Diseases
  • Genetic Linkage
  • Genetic Mutations
  • Genital Ulcers
  • Gentamicin 💊
  • Geriatric Medicine Emergencies: Revision ✅
  • Geriatric Medicine Syllabus (For Resident Doctors in Training)
  • Gerstmann-Straussler-Scheinker Syndrome (GSS)
  • Gestational Diabetes Mellitus ✅
  • Giardiasis
  • Gilbert's syndrome ✅
  • Gingival (Gum) hyperplasia or hypertrophy
  • Gitelman's syndrome
  • Glasgow Coma scale
  • Glatiramer acetate (Copaxone) 💊
  • Glibenclamide 💊
  • Gliclazide
  • Glimepiride
  • Glioblastoma ✅
  • Glipizide
  • Glomerulonephritis
  • Glossitis
  • Glossopharyngeal Nerve (Cranial Nerve IX)
  • Glucagon 💊
  • Glucagonoma
  • Glucose 6 phosphate dehydrogenase deficiency
  • Glucose Metabolism
  • Glucose Tolerance Test
  • Glutamate
  • Glycated Haemoglobin HbA1c
  • Glyceryl Trinitrate (GTN) 💊
  • Glycogen storage diseases
  • Glycolysis Krebs Electron Transport Chain
  • Glycopyrronium Bromide
  • Goitre ✅
  • Gold Score: Hypoglycaemia Awareness in Type 1 Diabetes ✅
  • Golfer's Elbow (Medial Epicondylitis)
  • Golimumab (Simponi) 💊
  • Gonorrhoea
  • Goodpasture's syndrome (Anti GBM disease)
  • Goserelin (Zoladex) 💊
  • Government Benefits Available to People with Disabilities UK
  • Gradenigo's syndrome
  • Grades of Recommendation
  • Gradual change in or loss of vision
  • Gram Stain
  • Granuloma annulare
  • Granulomas
  • Granulomatosis with Polyangiitis GPA (Wegeners)✅
  • Graves Disease (Thyrotoxicosis) ✅
  • Griseofulvin 💊
  • Grover Syndrome (Transient Acantholytic Dermatosis
  • Growth Hormone Deficiency ✅
  • Guillain Barre Syndrome
  • Gum hypertrophy
  • Gynaecological Examination (OSCE)
  • Gynaecological History Taking
  • Gynaecology: Fertility Contraception Menopause
  • Gynaecology: Menstrual Disorders
  • Gynaecology: Pelvic floor ovary and vulva
  • Gynaecology: Sexual health
  • Gynaecomastia ✅
  • HAM- D Hamilton Anxiety Rating Scale
  • HAM-A: Hamilton Anxiety Rating Scale
  • HAS-BLED score
  • HIV and Post-Exposure Prophylaxis (PEP)
  • HIV and Pre-exposure prophylaxis
  • HIV associated nephropathy (HIVAN)
  • HIV disease New Diagnosis
  • HTLV-1 Associated myelopathy (Tropical Spastic Paraparesis)
  • Haematemesis
  • Haematology Emergencies: Revision ✅
  • Haematology Laboratory Values
  • Haematology Revision Guide ✅
  • Haematology: Anaemia
  • Haematology: Anatomy Physiology and Pharmacology
  • Haematology: Emergencies
  • Haematology: Haemoglobinopathies and Transfusion
  • Haematology: Haemostasias and Thrombosis
  • Haematology: History and Examination
  • Haematology: Leukaemias, myeloproliferative neoplasms and myelodysplasia
  • Haematology: Malignancies
  • Haematology: Myeloma and Lymphoma
  • Haematopoietic Stem Cell Transplantation (Previously Bone Marrow Transplantation)
  • Haematospermia
  • Haematuria
  • Haemoglobinopathies
  • Haemoglobins
  • Haemolytic Anaemia
  • Haemolytic Uraemic Syndrome (HUS) ✅
  • Haemolytic disease of the newborn
  • Haemophagocytic Lymphohistiocytosis (HLH)
  • Haemophilia
  • Haemophilia A ✅
  • Haemophilia B ✅
  • Haemophilus aegyptius
  • Haemophilus ducreyi
  • Haemophilus influenzae
  • Haemophilus parainfluenzae
  • Haemopoiesis
  • Haemoptysis
  • Haemorrhagic Transformation of Infarction
  • Haemorrhagic stroke
  • Haemorrhoids (Piles) ✅
  • Hairy Cell Leukaemia
  • Hairy Leukoplakia
  • Hallervorden-Spatz disease (PKAN)
  • Haloperidol 💊
  • Hamman-Rich syndrome
  • Hand foot and mouth disease
  • Hand fractures and Injuries
  • Hantavirus infections
  • Haptoglobins
  • Harlequin ichthyosis
  • Hartmann's procedure
  • Hartmanns solution (Ringers lactate) 💊
  • Hartnup disease
  • Hashimoto's thyroiditis
  • Head Impulse Test
  • Head Injury and Traumatic Brain Head Injury (TBI)
  • Head Lice
  • Head and Neck Cancers
  • Headache - Basilar Migraine
  • Headache - Cluster
  • Headache - Medication Overuse Headache ✅
  • Headaches
  • Health Issues In Pregnancy
  • Health Safety and Manual Handling
  • Hearing Loss
  • Hearing aids
  • Heart Block
  • Heart Murmurs
  • Heart and Fetal circulation
  • Heat Stroke
  • Helicobacter pylori
  • Helvetica Spotted fever
  • Heme Synthesis, Biochemistry, and Physiology
  • Henoch-Schonlein purpura
  • Heparin - General 💊
  • Heparin - Low Molecular Weight Heparin 💊
  • Heparin - Unfractionated Heparin 💊
  • Heparin-induced thrombocytopenia (HIT) ✅
  • Hepatic Encephalopathy
  • Hepatitis (D) Delta Virus ✅
  • Hepatitis A ✅
  • Hepatitis B ✅
  • Hepatitis C
  • Hepatitis E ✅
  • Hepatocellular Carcinoma
  • Hepatology Emergencies: Revision
  • Hepatorenal syndromes
  • Hereditary Angio-Oedema
  • Hereditary Elliptocytosis 🩸
  • Hereditary Haemochromatosis
  • Hereditary Haemorrhagic Telangiectasia (HHT) ✅
  • Hereditary Spastic Paraparesis
  • Hereditary Spherocytosis (HS) 🩸
  • Hereditary neuropathy with pressure palsies
  • Hereditary non polyposis coli (Lynch syndrome) ✅
  • Hernias
  • Hernias (Children)
  • Herpes Simplex Encephalitis (HSV)
  • Herpes Simplex Virus
  • Herpes Varicella-Zoster (Shingles) Infection
  • Herpes Virus 6 and 7
  • Herpes Viruses
  • Herpes Zoster Ophthalmicus (HZO) Shingles
  • Herpes simplex keratitis (HSK)
  • Herpetic Whitlow
  • Heterochromia Iridium
  • Heyde syndrome
  • Hiatus hernia
  • Hiccups (Singultus)
  • Hidradenitis suppurativa (Acne Inversa)
  • Hierarchy of Evidence-Based Trials
  • High Altitude Physiology
  • High Dose Insulin Euglycaemic Therapy (HIET)
  • High Output Stoma
  • High Yield Cardiology
  • High Yield Endocrinology
  • High Yield Exam Geriatric
  • High Yield Gastroenterology
  • High Yield Infectious Diseases
  • High Yield Neurology
  • High Yield Renal / Electrolytes
  • High Yield Respiratory
  • High Yield Rheumatology / Autoimmune
  • High-Yield Oncology & Haematology
  • Hip Osteoarthritis ✅
  • Hip Pain (OSCE focused)
  • Hip pain in children
  • Hirschsprung disease (congenital megacolon)
  • Hirsuitism
  • Histones
  • Histoplasmosis
  • Hoarseness and voice change
  • Hodgkin Lymphoma ✅
  • Hodgkin vs Non-Hodgkin Lymphoma:
  • Holt-Oram syndrome
  • Holter monitor (tape) 24-72 h
  • Homocystinuria
  • Hookworm
  • Horner's syndrome
  • Horseshoe Kidney
  • Hospital acquired Pneumonia HAP ✅
  • Hospital-acquired infections
  • How does a CPU work
  • How to Read and Analyze a Medical Paper
  • Human Herpesvirus 6A (HHV-6A)
  • Human Leukocyte Antigen (HLA) and its Role in Disease Associations
  • Human Metabolism
  • Human albumin solution (HAS)
  • Human papilloma virus infection
  • Human prion diseases
  • Humeral Fractures ✅
  • Hunter's syndrome (MPS-2)
  • Huntingtons Disease/Chorea
  • Hurler's syndrome (MPS-1)
  • Hutchinson-Gilford Progeria Syndrome (HGPS)
  • Hydatid disease (Echinococcus)
  • Hydatidiform mole
  • Hydralazine 💊
  • Hydrocephalus and Stroke
  • Hydrocortisone 💊
  • Hydrogen Bonds
  • Hydrogen and other Bonds
  • Hydrops fetalis
  • Hydroxocobalamin - Cyanocobalamin (B12) 💊
  • Hydroxocobalamin 💊
  • Hydroxychloroquine 💊
  • Hydroxyurea (Hydroxycarbamide)
  • Hyoscine (Buscopan) 💊
  • Hyper IgM syndrome
  • Hyperacute Stroke Care Pathway
  • Hyperbaric Oxygen therapy
  • Hypercalcaemia of Malignancy
  • Hypercalcaemia ✅
  • Hypercholesterolaemia
  • Hyperemesis Gravidarum
  • Hyperglycaemic Hyperosmolar State (HHS) ✅
  • Hyperinsulinaemic-euglycemic therapy (HIET)
  • Hyperkalaemia ✅
  • Hyperkalaemic and Hypokalaemic Periodic Paralysis
  • Hyperlipidaemia
  • Hypermagnesaemia
  • Hypernatraemia
  • Hyperparathyroidism
  • Hyperphosphataemia (High phosphate)
  • Hyperprolactinaemia
  • Hypertension in Children ✅
  • Hypertension in Pregnancy ✅
  • Hyperthermia and Hypothermia
  • Hypertriglyceridaemia (HTG)
  • Hypertrophic cardiomyopathy (HCM - HOCM) ✅
  • Hyperuricaemia
  • Hyperventilation Syndrome
  • Hyperviscosity syndrome
  • Hyphaema (US Hyphema)
  • Hypocalcaemia ✅
  • Hypoglossal Nerve (Cranial Nerve XII)
  • Hypoglycaemia
  • Hypogonadism
  • Hypogonadism (Female)
  • Hypokalaemia
  • Hypokalaemic Periodic Paralysis
  • Hypomagnesaemia ✅
  • Hyponatraemia ✅
  • Hypophosphataemia (Low phosphate)
  • Hypopituitarism (Pituitary Failure)
  • Hypospadias
  • Hypothermia✅
  • Hypothyroidism ✅
  • Hypoxia - Reacting to Low Oxygen Saturations
  • Hypoxic-Ischaemic Encephalopathy
  • ICH Classification and Severity Scores
  • ID: HIV, viral hepatitis and blood-borne viruses
  • ID: Hospital infection, the immunocompromised host, vaccination and public health
  • ID: How Infection Happens
  • ID: Sepsis, fever and serious bacterial infections
  • ID: Tropical and travel medicine
  • ID: Viral, fungal and parasitic infections
  • IHD: Chronic stable angina ✅
  • IL-12 receptor deficiency
  • IV Immunoglobulin (IVIG) 💊
  • Ibandronic acid (Bisphosphonate) 💊
  • Ibuprofen 💊
  • Icatibant 💊
  • Idarucizumab (Praxbind) 💊
  • Idiopathic Arthritis in Adults
  • Idiopathic Fascicular Left Ventricular Tachycardia
  • Idiopathic Intracranial hypertension ✅
  • Idiopathic Pulmonary Fibrosis
  • Idiopathic Ventricular Tachycardia (IVT)
  • IgA Nephropathy (Berger's disease)
  • Ileostomy vs Colostomy Table
  • Iliopsoas Abscess
  • Images - Spot diagnoses
  • Imaging for the MLA#1
  • Imaging for the MLA#2
  • Imatinib mesylate
  • Imipenem (Primaxin) with Cilastin 💊
  • Immediate management and assessment of the newborn
  • Immobility
  • Immune Reconstitution Syndrome
  • Immune Thrombocytopenic Purpura (ITP) 🩸
  • Immune response
  • Immune-Mediated Necrotizing Myopathy
  • Immunoglobulin G4-related disease (IgG4-RD)
  • Immunoglobulins and their role in Immunity
  • Impetigo
  • Important Metabolic Pathways
  • Impulse control disorders
  • In Situ Thrombosis 🩸
  • Incidental Findings (Incidentalomas)
  • Inclusion Body Myositis
  • Incubation periods
  • Indapamide 💊
  • Indications for Irradiated Blood Products
  • Indinavir (IND)
  • Infant feeding issues
  • Infantile Spasms (West Syndrome)
  • Infection Associated Cancers
  • Infection Prevention Control for NHS Staff
  • Infection Prevention Control for NHS Staff
  • Infection screening in Septic patient ✅
  • Infectious Colitis
  • Infectious Diarrhoea (OSCE focused)
  • Infectious Diseases Revision Guide ✅
  • Infectious Mononucleosis (EBV Most Often)
  • Infective Endocarditis
  • Infective Keratitis
  • Inferior Vena Cava Filter
  • Infertility & Subfertility
  • Inflammatory Bowel Disease
  • Inflammatory eye disease
  • Infliximab 💊
  • Influenza
  • Information Governance for NHS Staff
  • Inguinal Hernia
  • Inhaled Levodopa (Inbrija®)
  • Inherited Hyperbilirubinaemia Syndromes
  • Inherited Metabolic Diseases in Children
  • Initial Assessment of Malaria in Children
  • Injury Severity Score (ISS)
  • Insomnia - unable to sleep issues
  • Insulin Degludec (Tresiba)
  • Insulin Detemir (Levemir)
  • Insulin Glargine (Lantus, Abasaglar, Semglee, Toujeo)
  • Insulin Physiology
  • Insulin Pumps
  • Insulinoma
  • Interferon Beta 💊
  • Intermittent Claudication
  • Internal Capsule
  • Internal Jugular vein Cannulation
  • Internal; Decapitation
  • Internuclear Ophthalmoplegia
  • Interstitial Keratitis
  • Interstitial Lung Disease
  • Intestinal Ischaemia
  • Intestinal obstruction (Children)
  • Intestinal obstruction and Ileus
  • Intra Aortic Balloon Pump
  • Intraabdominal abscess
  • Intrauterine death ✅
  • Intravascular large B-cell lymphoma (IVLBCL)
  • Intravenous Iron Replacement
  • Intravenous fluids ✅
  • Intraventricular haemorrhage (neonates)
  • Introduction to Anaesthetics 💤
  • Introduction to Hormones
  • Introduction to Obstetrics and Gynaecology
  • Introduction to Psychiatry
  • Intubation and Mechanical Ventilation
  • Intussusception in Adults
  • Intussusception in Children ✅
  • Investigations
  • Iodine Physiology
  • Iodine deficiency Goitre
  • Ipratropium Bromide (Atrovent) 💊
  • Irbesartan 💊
  • Iritis (Anterior Uveitis)
  • Iron Salts 💊
  • Iron Studies
  • Iron Studies
  • Iron deficiency Anaemia 🩸
  • Iron toxicity⚠️
  • Irritable bowel syndrome ✅
  • Ischaemic Colitis
  • Ischaemic Stroke
  • Ischaemic Strokes in the Pons
  • Ischaemic heart disease (Complete Includes ACS management)
  • Isoniazid 💊
  • Isoprenaline 💊
  • Isosorbide Dinitrate 💊
  • Isosorbide mononitrate 💊
  • Isotretinoin (Accutane) 💊
  • Ispaghula Husk (Fybogel) 💊
  • Ivabradine 💊
  • Ivermectin
  • Jansen Disease
  • Janus kinase 2
  • Jaundice
  • Java Programming
  • Jervell and Lange-Nielsen syndrome
  • Job Syndrome (Hyper IgE syndrome)
  • Jugular Venous pressure
  • Junctional Tachycardia
  • Juvenile Dermatomyositis
  • Juvenile Idiopathic Arthritis (Stills Disease)
  • Juvenile Myoclonic epilepsy (JME)
  • Kallmanns syndrome
  • Kaposi sarcoma (KS)
  • Karnofsky performance status scale
  • Kawasaki disease
  • Keloids
  • Kennedy Syndrome (Spinal and Bulbar Muscular Atrophy (SBMA))
  • Keratoacanthoma
  • Keratoconus
  • Kernicterus
  • Ketamine bladder
  • Ketamine 💊
  • Ketoconazole 💊
  • Ketones
  • Klebsiella pneumonia
  • Kleine Levin Syndrome
  • Klinefelter Syndrome
  • Klumpke palsy
  • Knee Joint Structure and Form
  • Koebner phenomenon
  • Kugelberg-Welander Syndrome (Spinal Muscular Atrophy Type III)
  • Kuru
  • Kwashiorkor
  • L-Thyroxine (T4) 💊
  • Labetalol (Trandate) 💊
  • Labour and Complications
  • Labyrinthitis and Vestibular Neuronitis
  • Lac operon
  • Lacerations
  • Lacerations
  • Lactate
  • Lactate dehydrogenase (LDH)
  • Lactic acidosis
  • Lactobacillus acidophilus
  • Lactose Intolerance
  • Lactulose 💊
  • Lacunar Stroke Syndromes
  • Lady Windermere syndrome
  • Lambert-Eaton syndrome (LEMS)
  • Lamivudine (3TC) 💊
  • Lamotrigine 💊
  • Langerhans cell histiocytosis (LCH)
  • Language and Dysphasia
  • Lansoprazole 💊
  • Lanthanum
  • Large for Gestational Age (LGA)
  • Larva Currens (Strongyloides stercoralis)
  • Lassa haemorrhagic fever (LHF)
  • Lateral Medullary Syndrome
  • Law and Mental Health (UK)
  • Law and Mental Health (USA)
  • Laxatives 💊
  • Le Fort Fractures
  • Lead toxicity
  • Learning (Intellectual) disability
  • Leber hereditary optic neuropathy (LHON)
  • Lecanemab (Leqembi)
  • Leflunomide (Arava) 💊
  • Left Ventricular Outflow Tract (LVOT) Tachycardia
  • Legal definition of Blindness
  • Legionella Pneumophila
  • Leishmaniasis (Cutanenous and Visceral)
  • Lemierre's syndrome
  • Lenalidomide (Revlimid)
  • Length Dependent Polyneuropathy
  • Lennox-Gastaut syndrome
  • Lenticulostriate branch occlusion
  • Leprosy (Hansen’s disease)
  • Leptin
  • Leptomeningeal Metastases
  • Leptospira interrogans
  • Leptospirosis (Weil's Disease) (Notifiable)
  • Leriche syndrome (aortoiliac occlusive disease)
  • Lesch-Nyhan syndrome
  • Leukaemia
  • Leukoariosis
  • Leukocoria (White Pupillary Reflex) 👁️
  • Leukocyte alkaline phosphatase
  • Leukocytoclastic vasculitis
  • Leukotrienes
  • Levetiracetam (Keppra) 💊
  • Levobupivacaine
  • Levodopa 💊
  • Levomepromazine
  • Levosimendan 💊
  • Lhermitte Duclos Disease
  • Li Fraumeni syndrome
  • Lichen Planus ✅
  • Liddle's syndrome
  • Lidocaine(Lignocaine) 💊
  • Lightning strike
  • Limb Weakness
  • Limb girdle dystrophy
  • Limbic Encephalitis
  • Linagliptin (Trajenta) 💊
  • Linezolid
  • Liothyronine Sodium L-Triiodothyronine (T3) 💊
  • Lipid emulsion therapy - Intralipid 💊
  • Lipoatrophy
  • Lipoprotein lipase deficiency
  • Liraglutide (Victoza) 💊
  • Lisinopril 💊
  • Listerial Meningitis
  • Listeriosis
  • Lithium toxicity⚠️
  • Lithium 💊
  • Livedo Reticularis ✅
  • Liver Biopsy
  • Liver Examination (OSCE)
  • Liver Transplantation
  • Liver abscess ✅
  • Liver disease in Pregnancy
  • Local Anaesthetics for Suturing or other Procedures
  • Localisation of cortical function
  • Locked in Syndrome
  • Lofepramine 💊
  • Loffler's syndrome (Pulmonary Eosinophilia)
  • Loin Pain
  • Long COVID
  • Long QT syndrome (LQTS) Congenital
  • Long chain acyl-CoA dehydrogenase deficiency
  • Long term Oxygen therapy (LTOT)
  • Loop diuretics 💊
  • Loperamide 💊
  • Lopinavir 💊
  • Loratadine 💊
  • Lorazepam 💊
  • Losartan 💊
  • Loss of Libido
  • Loss of red reflex
  • Louse-Borne vs Tick-Borne Relapsing Fever
  • Louse-borne relapsing fever
  • Low CSF pressure Headache
  • Low Mood and Affective Disorders - Depression
  • Lower Gastrointestinal Bleeding ✅
  • Lower Limb Fractures
  • Lower Limb Fractures and Injuries
  • Lower Limb Neurology (OSCE)
  • Lower Limb Soft Tissue Injuries
  • Lower respiratory tract infection (Child)
  • Lown Ganong Levine Syndrome (LGL) AVRT
  • Lugol iodine 💊
  • Lumbar and Sacrum anatomy and function
  • Lumbar puncture
  • Lumbrosacral Radiculopathy
  • Lump in Groin
  • Lung Abscess
  • Lung Cancer ✅
  • Lung Empyema
  • Lung Transplant
  • Lupus Nephritis
  • Lupus Vulgaris
  • Lyme disease
  • Lymphadenopathy
  • Lymphocytes
  • Lymphocytic Hypophysitis
  • Lymphogranuloma Venereum (LGV)
  • Lymphoproliferative Disorders
  • Lyonization (X-Inactivation)
  • Lysergic acid diethylamide (LSD) Toxicity
  • Lysosomal storage diseases
  • MCAD Deficiency (Medium-Chain Acyl-CoA Dehydrogenase Deficiency)
  • MELAS
  • MR cholangiopancreatography (MRCP)
  • Macrocytic anaemia 🩸
  • Macroglossia
  • Macrophage activation syndrome (MAS)
  • Magnesium Physiology
  • Magnesium Sulphate - Sulfate
  • Magnetic resonance cholangiopancreatography
  • Magnetic resonance imaging
  • Major Disaster Plan
  • Major Histocompatibility complex
  • Makindo Book
  • Malabsorption - small intestine ✅
  • Malaria
  • Malaria Falciparum (Cerebral Malaria) ✅
  • Male Urethral Catheterisation
  • Malignant Ascites
  • Malignant Breast Disease
  • Malignant Hyperparathyroidism due to PTHrP
  • Malignant Hyperpyrexia (Malignant Hyperthermia)
  • Malignant Hypertension
  • Malignant MCA syndrome ✅
  • Malignant Melanoma ✅
  • Malignant pleural mesothelioma
  • Mallet Finger
  • Mallory-Weiss Tear
  • Malnutrition Adults and the Elderly
  • Malnutrition Universal Screening Tool
  • Malnutrition universal screening tool (MUST)
  • Management of Bites
  • Mannitol
  • Mantle cell lymphoma
  • Maple Syrup Urine disease
  • Marantic Endocarditis
  • Marasmus
  • Maraviroc (Celsentri) 💊
  • Marburg virus disease
  • Marchiafava Bignami syndrome
  • Marfan syndrome
  • Marginal Keratitis 👁️
  • Marginal Zone Lymphoma
  • Mask-Related Acne (Maskne)
  • Massive Haemorrhage and Massive Transfusion Protocol (MTP)
  • Mastoiditis
  • Maths and Physics Crib Sheets
  • Maturity Onset Diabetes of the Young (MODY)
  • McArdles disease (type V)
  • McCune Albright syndrome
  • Measles (notifiable)
  • Mebeverine 💊
  • Mechanical Thrombectomy for Ischaemic Stroke
  • Meckel diverticulum ✅
  • Meconium
  • Median Nerve
  • Medical Licensing Assessment Content Map (GMC)
  • Medical Tweetorial Links
  • Medical conditions affecting the Teeth
  • Medication Sick-Day Rules
  • Medicine of the older adult. Ageing, frailty and comprehensive geriatric assessment
  • Medicine of the older adult. Discharge, capacity, advance care planning and end of life
  • Medicine of the older adult.: Falls, syncope, mobility and fragility fractures
  • Medicine of the older adult: .Prescribing and deprescribing in older people
  • Medicine of the older adult: Delirium, dementia and mood in older people
  • Medicine of the older adult:. Continence, nutrition, skin and other geriatric syndromes
  • Medullary Sponge kidney
  • Medulloblastoma
  • Mefenamic acid 💊
  • Mefloquine (Larium)
  • Megaloblastic anaemia 🩸
  • Melaena
  • Melatonin
  • Melioidosis (Burkholderia pseudomallei)
  • Memantine Hydrochloride 💊
  • Membranous Glomerulonephritis
  • Memory Loss
  • Menetrier disease
  • Menieres disease
  • Meningioma
  • Menkes Disease
  • Menopause and Menopausal Problems 🌸 ✅
  • Menstrual cycle
  • Menstrual problems
  • Mental Capacity Act 2005
  • Mental Health Act 1983
  • Mental capacity concerns
  • Mental health problems in pregnancy or postpartum 🤰
  • Mercaptopurine 💊
  • Meropenem 💊
  • Mesalazine (Aminosalicylate) 💊
  • Mesangiocapillary Glomerulonephritis
  • Mesenteric Ischaemia
  • Mesenteric adenitis
  • Mesial temporal lobe epilepsy
  • Metabolic Syndrome X ✅
  • Metabolic acidosis
  • Metabolic alkalosis
  • Metachromic leukodystrophy
  • Metastatic Adenocarcinoma
  • Metastatic Calcification
  • Metastatic bone disease
  • Metastatic disease
  • Metformin 💊
  • Methaemoglobinaemia
  • Methanol Toxicity
  • Methicillin Resistant Staphylococcus Aureus ✅
  • Methodone 💊
  • Methods to reduce toxin absorption
  • Methotrexate 💊
  • Methylcellulose 💊
  • Methylprednisolone
  • Methylthioninium chloride (Methylene blue)
  • Metoclopramide 💊
  • Metolazone 💊
  • Metoprolol 💊
  • Metronidazole (Flagyl) 💊
  • Metyrapone (Metopirone) 💊
  • Miconazole 💊
  • Microangiopathic Haemolytic anaemia
  • Microbiology and Assessment of Streptococcus
  • Microcytic anaemia 🩸
  • Microscopic Polyangiitis✅
  • Microscopic colitis
  • Microstomia
  • Microtubules
  • Midazolam
  • Middle East Resp Syndrome (MERS) Coronavirus
  • Midodrine 💊
  • Mifepristone
  • Migraine✅
  • Miliary (Disseminated) Tuberculosis
  • Miller-Fisher syndrome
  • Milrinone
  • Milwaukee shoulder syndrome
  • Mini Mental State Examination (MMSE)
  • Minimal Change Disease Glomerulonephritis
  • Minocycline 💊
  • Minoxidil 💊
  • Mirabegron 💊
  • Mirizzi syndrome
  • Mirtazapine 💊
  • Mirvetuximab soravtansine (Elahere)
  • Miscarriage
  • Misoprostol 💊
  • Misplaced Nasogastric tube insertion
  • Mitochondria
  • Mitochondrial diseases
  • Mitosis and Meiosis
  • Mitral Regurgitation (Incompetence)
  • Mitral Stenosis ✅
  • Mitral Stenosis vs Regurgitation
  • Mitral Valve prolapse ❤️
  • Mittelschmerz
  • Mixed Connective Tissue Disease (MCTD)
  • Mobility aids
  • Modified Oxford Handicap Scale (MOHS)
  • Modified Rankin Score
  • Modified Valsalva
  • Molecular Structures for Medicine
  • Molluscum contagiosum
  • MonkeyPox (MPOX)
  • Monoclonal gammopathy Undetermined significance
  • Monocytes 🩸
  • Monogenic diabetes
  • Monosodium glutamate (MSG) syndrome
  • Montelukast 💊
  • Montreal Cognitive Assessment (MOCA)
  • Moraxella catarrhalis
  • Morphine Sulphate 💊
  • Morphological Blood film abnormalities and variants
  • Mosquito borne diseases
  • Most Common Cancers in the UK & Red Flags
  • Motor End Plate
  • Motor Neuron Disease (MND-ALS)
  • Moyamoya disease
  • Muckle Wells syndrome
  • Multifocal Atrial Tachycardia
  • Multifocal Motor Neuropathy with Conduction block
  • Multiple Antithrombotics Anticoagulants
  • Multiple Crib sheets
  • Multiple Endocrine Neoplasia type 1 (MEN1)
  • Multiple Endocrine Neoplasia type II (MEN2)
  • Multiple Myeloma
  • Multiple Organ Dysfunction Syndrome
  • Multiple Pregnancy
  • Multiple Sclerosis (MS) ✅
  • Multiple System Atrophy (MSA)
  • Mumps (Notifiable)
  • Muscle Pain Myalgia
  • Muscular Dystrophies
  • Musculocutaneous nerve
  • Musculoskeletal deformities
  • Musculoskeletal deformities
  • Myasthenia Gravis ✅
  • Mycophenolate mofetil 💊
  • Mycoplasma pneumoniae 🫁
  • Mycoplasmas
  • Mycosis Fungoides (Sezary Syndrome)
  • Myelin Oligodendrocyte Glycoprotein (MOG) & MOG Antibody-Associated Disease (MOGAD)
  • Myelodysplastic syndrome (Myelodysplasia) 🩸
  • Myelofibrosis 🩸
  • Myelopathy (Disorder of Spinal cord)
  • Myeloproliferative disorders ✅
  • Myeloproliferative vs Lymphoproliferative Disorders
  • Myobacterium avium Complex Infection
  • Myocardial perfusion
  • Myoclonus
  • Myoglobin
  • Myotomes
  • Myotonic dystrophy - Dystrophia myotonica
  • Myxoedema coma
  • N-Acetylcysteine (Parvolex) 💊
  • NICE Guidance Part 1 ✅
  • NICE Guidance Part 2 ✅
  • NICE Guidance Part 3 ✅
  • NICE and other guidelines links
  • NICE and other guidelines links✅
  • NSAID toxicity⚠️
  • Nail disorders Table
  • Naloxone (Narcan) Opiate antagonist 💊
  • Naproxen
  • Narcolepsy
  • Narrow Complex Tachycardia ❤️
  • Nasal Discharge
  • Nasal Obstruction
  • Nasal polyps
  • Natalizumab (Tysabri) 💊
  • National Early Warning Score NEWS 2 Score
  • National Institutes of Health Stroke Scale (NIHSS)
  • Natural Language processing
  • Neck Swellings by Triangle
  • Necrotising Enterocolitis
  • Necrotising fasciitis
  • Needlestick injury and PEP
  • Nefopam 💊
  • Neisseria meningitidis (Meningococcus)
  • Nelson Syndrome
  • Nemaline myopathy
  • Neomycin 💊
  • Neonatal Abstinence Syndrome NAS
  • Neonatal Jaundice
  • Neonatal Lupus Erythematosus
  • Neonatal death or cot death
  • Neonatal death or cot death
  • Neonatal meningitis
  • Neostigmine 💊
  • Nephritic vs Nephrotic syndrome
  • Nephroblastoma (Wilm's tumour)
  • Nephrology Revision Guide ✅
  • Nephrotic Syndrome in Children ✅
  • Nephrotic syndrome in Adults
  • Nephrotoxic drugs
  • Nerve conduction studies
  • Neuroanatomy Images
  • Neuroblastoma
  • Neurocysticercosis (Taenia solium a pork parasite)
  • Neuroferrinopathy
  • Neurofibromatosis Type 1
  • Neurofibromatosis Type 2
  • Neuroleptic Malignant Syndrome
  • Neurological Examination - Cortical Functions
  • Neurological Examination - Motor
  • Neurological Examination - Speech&Language
  • Neurological Sensory Examination (OSCE)
  • Neurological examination - Eyes
  • Neurological or ENT Examination - Nystagmus
  • Neurological signs
  • Neurology Chapter
  • Neurology Crib Sheets
  • Neurology Revision Guide ✅
  • Neurology: Basics
  • Neurology: Dementia and Cognition Disorders (Complete)
  • Neurology: Emergencies
  • Neurology: Epilepsy
  • Neurology: Headache and Facial Pain
  • Neurology: Localisation and Investigation
  • Neurology: Movement Disorders
  • Neurology: Multiple Sclerosis and inflammatory disease
  • Neurology: Neuromuscular disease
  • Neurology: Oncology and Hydrocephalus
  • Neurology: Spine and Sleep Disorders
  • Neurology: Stroke Emergencies (Complete)
  • Neuromuscular weakness
  • Neuromyelitis Optica (Devic's disease)
  • Neuropathic Pain Management
  • Neuropathic pain
  • Neuroscience - Vision and Eye movements
  • Neuroscience of Memory
  • Neurosurgery
  • Neurotransmitters
  • Neutropenia
  • Neutropenic Sepsis
  • Neutrophil Alkaline Phosphatase
  • Neutrophils
  • Nevirapine (Viramune) NEV-NVP 💊
  • New Headache (OSCE focused)
  • New Onset Weakness (OSCE focused)
  • Newborn Bloodspot (Heel Prick) Screening
  • Niacin deficiency (Pellagra Vitamin B3)
  • Nicardipine (Cardene)
  • Nicorandil 💊
  • Niemann-Pick disease
  • Nifedipine 💊
  • Night sweats
  • Nikolsky's sign
  • Nimodipine (Nimotop) 💊
  • Nipple Discharge
  • Nirsevimab (Beyfortus)
  • Nitrates
  • Nitric Oxide
  • Nitrofurantoin 💊
  • Nitrous oxide use and abuse
  • Nizatidine 💊
  • Nocardia
  • Noise induced hearing loss
  • Non Alcoholic Fatty Liver Disease MASLD and MASH
  • Non Convulsive Status Epilepticus
  • Non Hodgkin Lymphoma ✅
  • Non gonococcal urethritis
  • Non invasive ventilation (NIV)
  • Non steroidal anti inflammatory drugs (NSAIDs) 💊
  • Non-Arteritic Anterior Ischaemic Optic Neuropathy 👁️
  • Non-accidental injury
  • Non-accidental injury (children)
  • Noonan syndrome
  • Noradrenaline (Norepinephrine) 💊
  • Normal Distribution
  • Normal Pressure Hydrocephalus
  • Normal Saline 0.9% ✅
  • Normal pregnancy and Antenatal care
  • Normocytic anaemia
  • Norovirus
  • Nortriptyline 💊
  • Norwegian Scabies ✅
  • Nosocomial infections
  • Notifiable disease and organisms UK
  • Nucleotides
  • Nutrition in Infants Breastfeeding
  • Nystatin 💊
  • OSCE Abdominal Examination
  • OSCE Ascites Examination
  • OSCE Blood pressure
  • OSCE Breast Anatomy Exam
  • OSCE Cardiac History Taking
  • OSCE Causes of Male Infertility
  • OSCE Cranial nerves and examination
  • OSCE Dysphagia Swallowing
  • OSCE Ear Examination
  • OSCE Examination of Visual Fields
  • OSCE Examining for Finger Clubbing
  • OSCE Examining the Arterial Pulse
  • OSCE Examining the Jugular Venous Pressure (JVP)
  • OSCE Eye Examination
  • OSCE Failure to Thrive
  • OSCE Gastroenterology History taking
  • OSCE Inguinal Examination
  • OSCE Jaundice
  • OSCE Leg Pain & Swelling
  • OSCE Lower Limb Neurological Examination
  • OSCE Male Genital exam
  • OSCE Monocular loss of vision
  • OSCE Neurological Examination - Cognition
  • OSCE Neurological Examination Face
  • OSCE Neurology - History taking
  • OSCE Rectal Bleeding
  • OSCE Respiratory - History Taking
  • OSCE Shoulder exam
  • OSCE Station Hearing Loss
  • OSCE Station – Melaena
  • OSCE Testicular/Scrotal Examination
  • OSCE Thyroid Exam
  • OSCE Unintentional Weight Loss
  • OSCE Upper Limb Neurology Examination
  • Obesity
  • Obesity and Pregnancy
  • Object orientated programming
  • Obsessive-Compulsive disorder
  • Obstetric definitions
  • Obstetrics
  • Obstetrics Emergencies: Revision✅
  • Obstetrics and Gynaecology Revision Guide ✅
  • Obstetrics: Antenatal Care
  • Obstetrics: Complications
  • Obstetrics: Medical Problems
  • Obstetrics: Obstetrics: Emergencies
  • Obstetrics: Post Natal Care
  • Obstructive Lung Diseases
  • Obstructive Shock (Mechanical Obstruction)
  • Obstructive Sleep Apnoea
  • Occupational Lung Disease
  • Octreotide 💊
  • Oculomotor Nerve (Cranial Nerve III)
  • Oesophageal Carcinoma
  • Oesophageal Perforation - Rupture
  • Oesophageal Variceal Bleeding
  • Oesophagogastroduodenoscopy (OGD/EGD)
  • Olanzapine 💊
  • Older Patient with Swallowing Problems
  • Olecranon Fracture
  • Olfactory Nerve (Cranial Nerve I)
  • Oligodendroglioma
  • Olmersartan 💊
  • Olsalazine (Aminosalicylate) 💊
  • Omalizumab
  • Omeprazole 💊
  • Onchocerciasis
  • Oncogenic viruses
  • Oncology Revision Guide ✅
  • Oncology: Breast and Gynae Cancers
  • Oncology: Emergencies
  • Oncology: Principles
  • Oncology: Skin Cancer
  • Oncology: Urology and Genital cancers
  • Ondansetron 💊
  • Ophthalmic Emergencies: Revision ✅
  • Ophthalmic Nerve
  • Ophthalmology Basics Cataract Glaucoma
  • Ophthalmology Exam Lists
  • Ophthalmology Revision Guide ✅
  • Ophthalmology: Neuro-ophthalmology
  • Ophthalmology: Paediatrics
  • Ophthalmology: Red emergencies
  • Ophthalmology: Retinal Visual Loss
  • Opiates 💊
  • Opicapone 💊
  • Opioid/Opiate toxicity⚠️
  • Opsonisation
  • Optic Nerve (Cranial Nerve II) and tract
  • Optic Neuritis
  • Optic atrophy
  • Optics Pathway
  • Oral Aphthous Ulcers
  • Oral Candidiasis
  • Oral Leukoplakia
  • Orbital Cellulitis vs Preorbital Cellulitis
  • Orf (Contagious Ecthyma)
  • Organism and sensitivities
  • Organomegaly
  • Organophosphate (OP) Toxicity
  • Orphenadrine
  • Orthopaedics Revision Guide ✅
  • Orthostatic Hypotension
  • Orthostatic Hypotension
  • Oseltamivir - Tamiflu 💊
  • Osteoarthritis
  • Osteochondroma
  • Osteogenesis Imperfecta
  • Osteogenic sarcoma (Osteosarcoma)
  • Osteomalacia
  • Osteomyelitis ✅
  • Osteonecrosis of the jaw
  • Osteopetrosis
  • Osteoporosis ✅
  • Otitis Externa (Malignant)
  • Otitis Media
  • Otosclerosis
  • Ottawa rules for ankle and foot x-ray
  • Ovarian Cancer
  • Ovarian Cyst
  • Ovarian Torsion
  • Overlap Syndrome
  • Oxford / Bamford Classification
  • Oxford Hip Score ✅
  • Oxford community stroke project (Bamford)
  • Oxidation and Reduction for Medical Students
  • Oxybutynin (Ditropan) 💊
  • Oxycodone (Oxycontin-Oxynorm) 💊
  • Oxygen delivery devices
  • Oxygenation and Ventilation
  • Oxytetracycline 💊
  • POEMS syndrome
  • Pabrinex 💊
  • Pacemakers
  • Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
  • Paediatric Crib Sheets
  • Paediatric emergencies
  • Paediatrics Revision Guide ✅
  • Paediatrics: Gastroenterology and surgery in children
  • Paediatrics: Growth, development and nutrition
  • Paediatrics: Infections in children
  • Paediatrics: Kidneys, urinary tract and hormones in children
  • Paediatrics: Neonatology
  • Paediatrics: Neurology, bones and joints in children
  • Paediatrics: Respiratory and heart problems in children
  • Pagets (Bone) disease
  • Pain Management : Acute & Chronic
  • Pain on inspiration
  • Painful Sexual Intercourse (Dyspareunia)
  • Painful Shoulder syndromes
  • Painful swollen leg
  • Palliation - Nausea Dyspnoea Secretions Pain
  • Palliation prescribing
  • Palliative Care Revision Article ✅
  • Palliative: End of Life Care
  • Palliative: Symptoms Management
  • Pallor
  • Palpitations
  • Pamidronate (Bisphosphonate) 💊
  • Panayiotopoulos Syndrome in Children
  • Pancoast tumour (Cancer)
  • Pancreatic Cancer
  • Pancytopenia
  • Panic Disorder
  • Panton-Valentine leucocidin toxin
  • Pantoprazole 💊
  • Pantothenate Kinase–Associated Neurodegeneration
  • Papilloedema
  • Paracetamol (Acetaminophen) toxicity⚠️
  • Paracetamol (Acetaminophen) 💊
  • Paracoccidioidomycosis
  • Paradoxical embolisation
  • Paraneoplastic Limbic Encephalitis (Dementia)
  • Paraneoplastic cerebellar degeneration
  • Paraphimosis (urological emergency)
  • Paraquat toxicity⚠️
  • Parkinson Plus syndromes
  • Parkinson disease
  • Parkinsonism
  • Parkinsonism–hyperpyrexia syndrome
  • Paronychia
  • Parotitis
  • Paroxetine 💊
  • Paroxysmal Nocturnal Haemoglobinuria
  • Pasteurella multocida
  • Patau syndrome (trisomy 13)
  • Patellar Bursitis
  • Patent Ductus arteriosus (PDA) ❤️
  • Patent Foramen Ovale (PFO)
  • Pathological Gaits 🚶‍♂️
  • Pathological bone fracture
  • Patient on Anticoagulant and Antiplatelet Therapy
  • Patients who refuse treatment or lack capacity
  • Patiromer 💊
  • Pattern Recognition Receptors
  • Pectus Excavatum
  • Pegvisomant 💊
  • Pelvic Abscess
  • Pelvic Inflammatory Disease ✅
  • Pelvic Mass
  • Pelvic Pain
  • Pelvic fractures
  • Pemphigoid Gestationis (Herpes Gestationis) ✅
  • Pemphigus Vulgaris
  • Penetrating Abdominal Trauma ✅
  • Penicillamine 💊
  • Penicillin Allergy
  • Penicillins 💊
  • Penile Cancer
  • Peptic ulcer disease (PUD) and gastritis in Children
  • Peptic ulcer disease and Gastritis in Adults
  • Percutaneous Endoscopic Gastrostomy (PEG) procedure:
  • Pergolide
  • Perianal abscesses and fistulae ✅
  • Perianal symptoms
  • Pericardial Disease
  • Pericardial Effusion and Tamponade ✅
  • Perimesencephalic Subarachnoid haemorrhage ✅
  • Perindopril 💊
  • Perinephric abscess
  • Perioperative Anticoagulation
  • Perioperative Medicine ✅
  • Peripheral Arterial Disease (PAD) ✅
  • Peripheral Nerve Palsies
  • Peripheral nerve injuries/palsies (Children)
  • Peripheral neuropathy
  • Peripheral oedema and ankle swelling
  • Peripherally inserted central catheters (PICC)
  • Peritonitis
  • Peritonsillar Abscess (Quinsy) ✅
  • Pernicious anaemia
  • Personality Disorders
  • Perthes disease (Osteochondritis of the Hip)
  • Petechial Rash in Adult or Child
  • Pethidine
  • Peutz-Jeghers syndrome
  • Peyronie’s Disease
  • Phaeochromocytoma
  • Phagocytes
  • Pharmacokinetic
  • Pharmacokinetics
  • Pharmacology in the Elderly
  • Pharyngeal arch derivatives
  • Pharyngitis
  • Phenobarbital sodium
  • Phenoxymethylpenicillin (Penicillin V) 💊
  • Phentolamine 💊
  • Phenylketonuria (PKU)
  • Phenytoin (Dilantin) 💊
  • Philadelphia chromosome
  • Phimosis
  • Phobic disorders
  • Phocomelia and Thalidomide
  • Phosphorus/Phosphate
  • Phthiriasis palpebrarum ✅
  • Physical Education
  • Physics of flow for Medical students
  • Picolax - Citrafleet 💊
  • Pilonidal Abscess (sinus) ✅
  • Pinta (Treponema carateum)
  • Pioglitazone (Thiazolidinediones) 💊
  • Pituitary Apoplexy
  • Pituitary Tumours
  • Pityriasis or Tinea versicolor infections
  • Pityriasis rosea
  • Pivmecillinam (a penicillin antibiotic) 💊
  • Placenta praevia
  • Placental abruption
  • Plantar fasciitis
  • Plasmapheresis
  • Plasmids
  • Platelets
  • Pleural effusion
  • Pleural tap (thoracentesis)
  • Pneumococcal meningitis ✅
  • Pneumoconiosis ✅
  • Pneumocystis jirovecii pneumonia
  • Pneumonia in Children
  • Pneumonia 🩺 (OSCE focused)
  • Poisoning
  • Poisons eliminated Haemodialysis - perfusion
  • Poliomyelitis
  • Polyarteritis nodosa (PAN)
  • Polyarticular arthritis
  • Polycystic Ovary syndrome
  • Polycythaemia
  • Polycythaemia Vera (Primary Polycythaemia) ✅
  • Polydipsia (thirst)
  • Polymerase chain reaction
  • Polymorphic light eruption
  • Polymyalgia Rheumatica
  • Polymyositis
  • Polypharmacy and STOPP/START criteria
  • Polyuria
  • Polyuria and Thirst (OSCE focused)
  • Pontiac fever (Legionella Pneumophila)
  • Pontine-Midbrain haemorrhage ✅
  • Popliteal Artery Aneurysm
  • Porphyria Cutanea Tarda (PCT)
  • Porphyria Testing
  • Portal Hypertension
  • Positron and Single photon Emission Tomography
  • Post Falls Assessment
  • Post Menopausal Bleeding
  • Post Partum Thyroiditis
  • Post Polio Syndrome (PPS)
  • Post Streptococcal/Infectious Glomerulonephritis
  • Post Stroke Epilepsy (PSE)
  • Post-Traumatic Stress Disorder (PTSD)
  • Post-exposure prophylaxis with Immunoglobulins
  • Post-operative surgical care and complications
  • Post-transplant lymphoproliferative disorders (PTLDs)
  • Posterior Reversible Encephalopathy Syndrome (PRES)
  • Posterior circulation
  • Postmenopausal Bleeding (OSCE focused)
  • Postnatal Depression
  • Postpartum Haemorrhage ✅
  • Postpartum Psychosis
  • Postprandial hypotension
  • Postural Orthostatic Tachycardia Syndrome (POTS)
  • Post‑fall management: Concerns for the On‑Call Team
  • Potassium Physiology
  • Pralidoxime 💊
  • Pramipexole (Mirapexin) 💊
  • Prasugrel 💊
  • Pravastatin 💊
  • Praziquantel
  • Prazosin 💊
  • Pre-Operative Assessment
  • Pre-eclampsia, Gestational Hypertension
  • Prednisolone 💊
  • Prednisone 💊
  • Pregabalin 💊
  • Pregnancy risk assessment
  • Premature Menopause
  • Prematurity
  • Premed Anatomy
  • Premed Pathology 🔬
  • Premed Pharmacology
  • Premedical Biochemistry
  • Premedical Immunology 🧠
  • Premedical Microbiology 🧫
  • Presbyacusis(Presbycusis)
  • Prescribing in Pregnancy
  • Pressure sores or ulcers
  • Preterm labour
  • Prevotella (Bacteroides) melaninogenica
  • Priapism ✅
  • Primaquine
  • Primary Biliary Cholangitis
  • Primary CNS Lymphoma (PCNSL)
  • Primary Familial Brain Calcification (PFBC) Fahr Syndrome
  • Primary Open-Angle Glaucoma (POAG)
  • Primary Pulmonary Hypertension
  • Primary Sclerosing Cholangitis
  • Primary amoebic meningoencephalitis (PAM)
  • Primary and Secondary Hypoparathyroidism ✅
  • Primary ciliary dyskinesia and Kartagener's syndrome
  • Primary hyperaldosteronism (Conn's syndrome)
  • Primary progressive aphasia (Dementia)
  • Probenecid 💊
  • Procalcitonin (PCT) 🧪
  • Prochlorperazine (Stemetil) 💊
  • Procyclidine
  • Progressive Multifocal Leukoencephalopathy (PML)
  • Progressive Supranuclear Palsy (PSP)
  • Prolactin
  • Prolactinoma ✅
  • Propafenone 💊
  • Propantheline 💊
  • Propionibacterium
  • Propofol 💊
  • Propranolol 💊
  • Propylthiouracil 💊
  • Prostate cancer✅
  • Prosthetic Metal and Tissue Valves
  • Protamine Sulfate 💊
  • Protein C Deficiency ✅
  • Protein S Deficiency
  • Protein Synthesis
  • Protein losing enteropathy
  • Protein metabolism
  • Protein p53
  • Proteus
  • Prothrombin 20210A mutation
  • Prothrombin Complex Concentrates (Octaplex and Beriplex) 💊
  • Prothrombin time and Coagulation 🩸
  • Prothrombotic Hypercoagulable disorders
  • Proximal myopathy
  • Prucalopride
  • Pruritis
  • Pruritis ani
  • Psammoma bodies 🌀
  • Pseudo(pseudo)hypoparathyroidism
  • Pseudomonas infection (Pseudomonas aeruginosa)
  • Psoriasis
  • Psoriatic arthritis ✅
  • Psychiatric emergencies
  • Psychiatry Revision Guide✅
  • Psychiatry: Alcohol, drugs and addiction
  • Psychiatry: Anxiety, stress and somatic disorders
  • Psychiatry: Mood disorders
  • Psychiatry: Personality, eating and neurodevelopmental disorders
  • Psychiatry: Psychosis and schizophrenia
  • Psychiatry: Safeguarding
  • Psychiatry: assessment, treatment and the law
  • Psychogenic Polydipsia
  • Pubertal Development
  • Pubic Lice (Pediculosis Pubis)
  • Pulmonary Alveolar Proteinosis
  • Pulmonary Arteriovenous malformation
  • Pulmonary Arteriovenous malformation
  • Pulmonary Embolism 🫁
  • Pulmonary Eosinophilia and CXR changes
  • Pulmonary Haemorrhage
  • Pulmonary Hypertension
  • Pulmonary Regurgitation ❤️
  • Pulmonary Stenosis ❤️
  • Pulmonary-renal syndromes ✅
  • Pulmonry Embolism in Pregnancy 🤰
  • Pulse oximetry
  • Pupils : Relative Afferent pupillary defect (RAPD)
  • Purpura
  • Purpura Fulminans
  • Putamen and Globus Pallidus
  • Putaminal Haemorrhage
  • Pyloric Stenosis Children
  • Pyoderma gangrenosum ✅
  • Pyonephrosis
  • Pyrazinamide 💊
  • Pyridostigmine 💊
  • Pyroglutamic acidosis
  • Pyruvate Kinase deficiency
  • Python Programming
  • QRISK3 (OSCE focused) ❤️
  • Quetiapine 💊
  • Quinine toxicity⚠️
  • Quinine 💊
  • RFS Rib fracture score
  • ROSIER scale
  • Rabies
  • Radial Head and Neck Fractures
  • Radial Ulnar and Median Palsy of the Hand
  • Radial nerve
  • Radiation exposure
  • Radicular syndromes
  • Radiculopathies
  • Radioactive iodine (I 131)
  • Radiofrequency Catheter Ablation
  • Radiologically Inserted Gastrostomy (RIG) Procedure
  • Radiology for finals
  • Raised intracranial pressure (ICP)
  • Raloxifene 💊
  • Raltegravir 💊
  • Ramipril 💊
  • Ramsay Hunt syndrome
  • Ranitidine 💊
  • Ranolazine 💊
  • Rapid Sequence Intubation (RSI)
  • Rapidly Progressive Glomerulonephritis (RPGN)
  • Rasagiline 💊
  • Rasburicase
  • Rate limiting steps in metabolism
  • Raynaud's Phenomenon Primary and Secondary
  • Reactive Arthritis
  • Rectal Foreign Body
  • Rectal Pain (Proctalgia)
  • Rectal Prolapse ✅
  • Rectal examination (OSCE)
  • Red Blood Cell Maturation
  • Red cell aplasia
  • Reduced/change in fetal movements
  • Refeeding syndrome
  • Referring to Level 2 or 3 care (ITU ICU HDU)
  • Reflex anoxic attacks in Children
  • Refractive Errors
  • Refsum disease
  • Regular Broad Complex Tachycardia ❤️
  • Rehabilitation in a Nutshell of older patients
  • Relapsing Polychondritis
  • Remdesvir (Veklury)
  • Renal Artery Stenosis Renovascular Disease
  • Renal Emergencies: Revision ✅
  • Renal Papillary Necrosis
  • Renal Replacement Therapy (RRT)
  • Renal Top Tips
  • Renal Transplantation
  • Renal Tubular Acidosis (RTA)
  • Renal Vein Thrombosis ✅
  • Renal cell carcinoma ✅
  • Renal syndromes
  • Renal: Basics
  • Renal: Chronic Kidney Disease
  • Renal: Dialysis and Transplant
  • Renal: Emergencies
  • Renal: Glomerular Disease
  • Renal: Tubular Inherited Stones (Complete)
  • Renin and Aldosterone Renin ratio (ARR)
  • Renin-angiotensin system
  • Respiratory Examination (OSCE)
  • Respiratory : Airways Disease
  • Respiratory : Interstitial Lung disease
  • Respiratory : Investigations
  • Respiratory : Lung Cancer
  • Respiratory Acidosis
  • Respiratory Alkalosis
  • Respiratory Arrest
  • Respiratory Crib Sheets
  • Respiratory Disease Investigations
  • Respiratory Distress Syndrome (Neonates)
  • Respiratory Emergencies: Revision✅
  • Respiratory Failure
  • Respiratory Revision Guide ✅
  • Respiratory Spirometry and Flow Volume Loops
  • Respiratory: Basics
  • Respiratory: Emergencies
  • Respiratory: Infections
  • Respiratory: Pulmonary Vascular Disease
  • Respiratory: Sleep and Breathing (Complete)
  • Restless legs syndrome
  • Restriction enzymes
  • Restrictive Cardiomyopathy
  • Resus: Septic Shock and Sepsis
  • Resuscitation - Acute Haemorrhage
  • Resuscitation - Adult Bradycardia Algorithm
  • Resuscitation - Adult Tachycardia Algorithm
  • Resuscitation - Advanced Life Support Cardiac Arrest
  • Resuscitation - Basic Life Support Cardiac Arrest
  • Resuscitation - Choking Algorithm
  • Resuscitation - Newborns and Children
  • Resuscitation - Post Resuscitation Algorithm
  • Reteplase 💊
  • Reticulocytes
  • Retinal detachment
  • Retinitis pigmentosa
  • Retinoblastoma 👁️
  • Retinoids 💊
  • Retinopathy of Prematurity (ROP) 👁️
  • Retroperitoneal fibrosis
  • Rett Syndrome
  • Reversible cerebral vasoconstriction syndrome (RCVS) ✅
  • Revision Core Syllabus Guide for Medical Students ✅
  • Reye syndrome
  • Rhesus haemolytic disease
  • Rheumatic fever ❤️
  • Rheumatoid Arthritis ✅
  • Rheumatology Autoantibodies
  • Rheumatology Drugs
  • Rheumatology Lab values
  • Rheumatology Revision Guide ✅
  • Rheumatology: Crystal arthritis, osteoarthritis and soft tissue pain
  • Rheumatology: Emergencies, pregnancy and other systemic diseases
  • Rheumatology: Inflammatory arthritis
  • Rheumatology: Vasculitis, GCA and PMR
  • Rheumatology: assessment, investigations and drugs
  • Rheumatology:Connective tissue diseases
  • Rhino-Orbital-Cerebral Mucormycosis
  • Rhinosinusitis
  • Rhodococcus equi
  • Ribavirin 💊
  • Ribosomes
  • Ricin Toxicity
  • Rickettsia (General Principles)
  • Rickettsia africae (Tick Bite Fever)
  • Rickettsia akari (Rickettsial pox)
  • Rickettsia conorii (Mediterranean Spotted Fever)
  • Rickettsia prowazekii (Epidemi/Louse-borne Typhus)
  • Rickettsia rickettsii (Rocky Mountain spotted fever)
  • Rickettsia tsutsugamushi (Scrub typhus)
  • Rickettsia typhi (Murine/Endemic typhus)
  • Rifampicin (Rifabutin Rifampin) 💊
  • Rifaximin 💊
  • Right Iliac Fossa Pain
  • Right Ventricular Outflow Tract Tachycardia (RVOT)
  • Right Ventricular ST Elevation MI (RVMI)
  • Right heart valve disease
  • Rilipivirine (Edurant) RVP 💊
  • Riluzole (Rilutek)
  • Risedronate (Bisphosphonate) 💊
  • Risperidone 💊
  • Ritonavir (Norvir) RTV 💊
  • Rituximab (Mabthera) 💊
  • Rivaroxaban (Xarelto) 💊
  • Rivastigmine (Exelon) 💊
  • Rocky Mountain Spotted Fever
  • Rocuronium 💊
  • Role of Urinary Catheters in the Elderly
  • Rosacea ✅
  • Rotavirus
  • Rotigotine Transdermal Patch (Neupro) 💊
  • Rubella (German Measles) Notifiable
  • Ruptured Ovarian Cyst ✅
  • Rust Programming
  • SCL70 Antibody
  • SCOFF questionnaire screening tool
  • SQL programming
  • SUSS test for eating disorder examinations
  • Saccular Berry Cerebral Aneurysms
  • Sacubitril with Valsartan 💊
  • Safeguarding Adults and Children
  • Safety Surgical checklist WHO
  • Salivary Gland Disease
  • Salivary glands
  • Salmonella enterica
  • Salmonella typhi
  • Sampling in Medical Statistics
  • Samter's Tiad
  • Saquinavir (Invirase) SQV 💊
  • Sarcoidosis
  • Saxagliptin (Onglyza) 💊
  • Scabies
  • Scaphoid fracture
  • Scarlet Fever (Scarlatina)
  • Scarring
  • Schamberg disease
  • Schistosomiasis
  • Schizophrenia
  • Schmidts syndrome
  • Sciatic nerve
  • Sciatica ✅
  • Scleritis
  • Scleroderma perforans of the sclera (scleromalacia perforans),
  • Scrotal/testicular pain/lump/swelling ⚠️
  • Seborrheic Dermatitis
  • Seborrheic Keratosis ✅
  • Secondary Hypertension
  • Secondary Messengers
  • Secondary Pulmonary hypertension - Cor pulmonale
  • Secondary dysmenorrhoea
  • Secondary hyperparathyroidism
  • Secondary prevention Post Acute Coronary Syndrome
  • Sedation and Analgesia on ITU
  • Selective IgA deficiency
  • Selective Serotonin reuptake Inhibitor toxicity⚠️
  • Selective serotonin reuptake inhibitors (SSRI) 💊
  • Selegiline 💊
  • Selenium deficiency
  • Self assessment form
  • Self-harm / Suicidal thoughts / Suicide ✅
  • Senior Self Assessment
  • Senna 💊
  • Septic Abortion ✅
  • Septic arthritis ✅
  • Seronegative Spondyloarthropathies
  • Serotonin syndrome
  • Serplulimab
  • Serratia
  • Sevelamer 💊
  • Severe combined immunodeficiency disorders
  • Shaft of Ulna Fracture
  • Sheehans syndrome
  • Shigella characteristics
  • Shigellosis (Bacillary Dysentery)
  • Shock in Pregnancy
  • Short QT Syndrome
  • Short Synacthen test (SST)
  • Shortness of Breath History (OSCE focused) 🫁
  • Shoulder Anterior Dislocations
  • Shoulder Joint Structure and Form
  • Shoulder: Posterior Dislocation
  • Sick Child/Neonate
  • Sick Euthyroid Syndrome ✅
  • Sick Sinus Syndrome (Tachy-Brady syndrome) 🫀
  • Sickle Cell Disease
  • Sideroblastic Anaemia
  • Sigmoid and Caecal Volvulus Adults
  • Sildenafil (Viagra) 💊
  • Silicosis
  • Simple Needle Aspiration for Spontaneous Pneumothorax
  • Simvastatin 💊
  • Sinus Bradycardia
  • Sinus Node disease
  • Sinus Tachycardia
  • Sinus arrhythmia 🫀
  • Sitagliptin 💊
  • Sitosterolemia
  • Sjögren’s syndrome
  • Skin Infections due to Fungi 🦠
  • Skin Pathology and Description and Examination
  • Skin Treatments
  • Skin Ulcers
  • Skin and soft tissue and bone infections ✅
  • Skin or subcutaneous lump
  • Skull Anatomy
  • Sleep physiology
  • Slipped Upper Femoral Epiphysis (SUFE)
  • Small Bowel Obstruction (Adults)
  • Small for Gestational Age (SGA)
  • Small vessel disease
  • Smallpox
  • Smoke Inhalation
  • Smoking and Its Consequence
  • Smooth and Rough Endoplasmic Reticulum
  • Smouldering Myeloma
  • Snake Bites
  • Sneddon Syndrome
  • Sodium Bicarbonate (NaHCO3)
  • Sodium Nitroprusside 💊
  • Sodium Physiology
  • Sodium Picosulfate 💊
  • Sodium Potassium ATPase pump
  • Sodium Thiopental - Sodium Thiopentone 💊
  • Sodium Valproate (Epilim Depakote) 💊
  • Sodium Zirconium Cyclosilicate (Lokelma)
  • Sodium Zirconium Cyclosilicate 💊
  • Soft Tissue Injury
  • Soft tissue : Cut finger
  • Soft tissue injuries (sprains, strains)
  • Solifenacin 💊
  • Solitary Pulmonary Nodule
  • Somatisation
  • Somatisation/ medically unexplained physical symptoms
  • Sore throat
  • Sotalol Hydrochloride 💊
  • Speech and language problems
  • Spina Bifida
  • Spinal Cord Arteriovenous Malformations
  • Spinal Cord Compression
  • Spinal Cord Haematoma
  • Spinal Cord Infarction
  • Spinal Cord Injury / Malignant Spinal Cord Compression (MSCC)
  • Spinal Fracture
  • Spinal Fractures: assessment & management
  • Spinal Muscular Atrophy (SMA) 🧠
  • Spinal Stenosis
  • Spinal Tracts
  • Spinal and Epidural Anaesthesia
  • Spironolactone 💊
  • Splenectomy
  • Splenectomy and Hyposplenism
  • Splenic Rupture
  • Splenomegaly Examination (OSCE)
  • Spondylolisthesis
  • Spontaneous Bacterial Peritonitis
  • Spontaneous Pneumothorax
  • Spontaneous intracranial hypotension
  • Sprained Ankle ✅
  • Squamous Cell Carcinoma
  • Squint
  • St John's Wort 💊
  • Staphylococcal Infections
  • Staphylococcus aureus
  • Staphylococcus epidermidis
  • Staphylococcus saprophyticus
  • Statin 💊
  • Status Epilepticus (Epilepsy/Seizure) ✅
  • Stavudine (Zerit) d4T 💊
  • Stem Cell Transplantation
  • Sterno-Clavicular Joint Dislocation
  • Steroid Sick-Day Rules
  • Steroid-responsive encephalopathy associated with autoimmune thyroiditis (Hashimoto's Encephalopathy)
  • Stiff Person Syndrome
  • Strabismus (Lazy Eye)
  • Streptobacillus moniliformis
  • Streptococcal Infections
  • Streptococcus - anaerobes
  • Streptococcus Pneumoniae (Pneumococcus)
  • Streptococcus agalactiae Group B
  • Streptococcus milleri
  • Streptococcus pyogenes Group A
  • Streptococcus viridans
  • Streptokinase 💊
  • Streptomycin 💊
  • Stridor
  • Stroke
  • Stroke - Epidemiology and risk factors
  • Stroke - General Management
  • Stroke Collaterals
  • Stroke Crib sheets
  • Stroke MRI Basics
  • Stroke Mimics And Chameleons
  • Stroke Penumbra
  • Stroke Recrudescence
  • Stroke Related Cerebral Perfusion
  • Stroke Risk Factors
  • Stroke Thrombolysis
  • Stroke Vascular Anatomy
  • Stroke and Vision
  • Strongyloides stercoralis (threadworm)
  • Strontium 💊
  • Sturge Weber syndrome
  • Subacute Thyroiditis
  • Subarachnoid Haemorrhage ✅
  • Subclavian Steal Syndrome
  • Subclavian Vein Thrombosis (SCVT)
  • Subdural haematoma
  • Subfertility in Men
  • Subfertility in Women
  • Substance misuse
  • Substance use disorder
  • Sucralfate 💊
  • Sudden Cardiac Death (SCD)
  • Sudden Sensorineural Hearing loss (SNHL)
  • Sugammadex 💊
  • Suicidal thoughts
  • Suicide
  • Sulfasalazine - Sulphasalazine 💊
  • Sumatriptan
  • Summary of Emergency Conditions in Oncology
  • Superior Mesenteric Artery (SMA) Syndrome
  • Superior Sagittal Sinus Thrombosis
  • Superior Vena Caval Obstruction syndrome
  • Superior and Inferior Vena Cava
  • Supracondylar Femur Fractures
  • Supracondylar Humerus Fractures
  • Supraspinatus tendonitis
  • Supraventricular Tachycardia (SVT)
  • Surgery :Hernias and the abdominal wall
  • Surgery Revision Guide ✅
  • Surgery: Acute abdomen and emergency general surgery
  • Surgery: Cardiothoracic, neurosurgery and plastic surgery
  • Surgery: Colorectal and anal surgery
  • Surgery: Major trauma and burns
  • Surgery: Surgical principles and perioperative care
  • Surgery: Upper GI, hepatobiliary and bariatric surgery
  • Surgery: Vascular surgery
  • Surgey: Breast and endocrine surgery
  • Surgey: Trauma and orthopaedics
  • Surgey: Urology
  • Surgical Cricothyroidotomy
  • Surgical Liaison in Older Patients Quality & Silver Trauma (UK)
  • Surgical Stomas
  • Surgical prophylaxis
  • Surgical site infection
  • Susac syndrome
  • Suxamethonium 💊
  • Sweat Test
  • Swiss Cheese Model of Patient Harm
  • Sydenhams chorea
  • Sympathetic Ophthalmia 👁️
  • Synchronised DC Cardioversion
  • Syncope
  • Syndrome of Inappropriate ADH (SIADH) secretion
  • Syphilis
  • Syringobulbia
  • Syringomyelia
  • Systemic Amyloid in Pathology
  • Systemic Amyloidosis
  • Systemic Lupus Erythematosus (SLE) ✅
  • Systemic Mastocytosis
  • Systemic Sclerosis (Scleroderma)
  • T lymphocytes
  • TMN Staging tumours
  • TNF Blockade
  • TNF receptor-associated periodic syndrome
  • TO DO
  • TORCH infections
  • TURP Hyponatraemia syndrome
  • Tabes dorsalis
  • Table showing Visual Field Changes for Examination
  • Tacrolimus 💊
  • Tafamidis
  • Takayasu arteritis (pulseless disease)
  • Takotsubo Cardiomyopathy ❤️
  • Tamoxifen
  • Tamsulosin (Flomax) 💊
  • Tangier Disease
  • Tardive Dyskinesias
  • Tay-Sachs disease
  • Tazocin (Tazobactam - Piperacillin) 💊
  • Teicoplanin 💊
  • Telogen Effluvium
  • Telomeres
  • Temazepam 💊
  • Temozolomide (Temodal) 💊
  • Temporal (Giant Cell GCA) Arteritis ✅
  • Tenecteplase 💊
  • Tennis Elbow (Lateral Epicondylitis)
  • Tensilon test
  • Tension Headache
  • Tension Pneumothorax
  • Teplizumab (Tzield)
  • Terbutaline
  • Teriparatide 💊
  • Terlipressin
  • Tertiary hyperparathyroidism
  • Testicular Cancer
  • Testicular Torsion ✅
  • Testing
  • Testosterone
  • Tests in Liver Disease: Usefulness and Interpretation
  • Tetrabenazine
  • Tetracosactide (Synacthen)
  • Tetracyclines 💊
  • Tetralogy of Fallot ✅
  • Thalamic Haemorrhage
  • Thalamic Pain Syndrome or Dejerine–Roussy Syndrome
  • Thalamic Strokes
  • Thalamus
  • Thalidomide 💊
  • The Aorta
  • The Axillary Artery
  • The Brachial Artery
  • The Brachial plexus
  • The Carotid Artery
  • The Cell Nucleus
  • The Cell membrane
  • The Circle of Willis
  • The Deteriorating Patient
  • The Eye and Systemic Disease
  • The Face 😀
  • The Femoral Artery
  • The Fetal Head and Vaginal Birth
  • The Iliac arteries
  • The Popliteal artery
  • The Radial and Ulnar Arteries
  • The Subclavian Artery
  • The Vertebral and Basilar Arteries
  • The unconscious (comatose) patient
  • Theophylline toxicity⚠️
  • Theophylline 💊
  • Thiamine 💊
  • Thoracic outlet syndrome
  • Thrombocytopenia
  • Thrombocytosis (High Platelets)
  • Thrombophilia (Prothrombotic) testing
  • Thrombotic Thrombocytopenic purpura (TTP)
  • Thunderclap Headache ✅
  • Thyroglossal Cyst (Children)
  • Thyroid Cancer
  • Thyroid Eye Disease
  • Thyroid Function Tests and antibodies
  • Thyroid Storm - Thyrotoxic crisis
  • Thyroid Surgery (Thyroidectomy)
  • Thyroid nodules ✅
  • Thyrotoxicosis and Hyperthyroidism
  • Tiagabine 💊
  • Ticagrelor
  • Tick Paralysis
  • Tick-borne relapsing fever (Borrelia duttonii)
  • Tilt Table Testing in Reflex Syncope
  • Timolol
  • Tinea Corporis and Tinea faciei(Ringworm) ✅
  • Tinea capitis
  • Tinea imbricata
  • Tinidazole
  • Tinnitus
  • Tinzaparin (Innohep)💊
  • Tiotropium (Spiriva) 💊
  • Titre - Titer
  • Tocilizumab 💊
  • Tolbutamide
  • Tolcapone 💊
  • Toll-like Receptors (TLRs): Recognition Receptors and Triggers of Innate Immunity
  • Tolosa Hunt Syndrome
  • Tolterodine 💊
  • Tolvaptan
  • Tongue tie - ankyloglossia (Children)
  • Tonsilitis
  • Tonsillectomy Adenoidectomy
  • Topical Steroids
  • Topiramate (Topamax) 💊
  • Torsades de pointes TdP (Polymorphic VT)
  • Total Anomalous Pulmonary Venous Drainage ❤️
  • Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson syndrome
  • Toxic Megacolon
  • Toxic Shock Syndrome ✅
  • Toxic Thyroid Adenoma
  • Toxicological Emergencies
  • Toxoplasmosis
  • Tramadol 💊
  • Tranexamic Acid 💊
  • Transcatheter aortic valve implantation/replacement (TAVI/R)
  • Transcutaneous Pacing
  • Transfer Factor (TLCO / DLCO)
  • Transferrin
  • Transfers of folder frail or disabled patients
  • Transient Global Amnesia (TGA)
  • Transient Ischaemic Attack (TIA)
  • Transient Monocular Blindness (TMB)
  • Transjugular Intrahepatic portosystemic shunt (TIPS)
  • Transposition of the great arteries (TGA)
  • Transvenous Pacing (Temporary)
  • Transverse myelitis
  • Trastuzumab (Herceptin) 💊
  • Trauma
  • Trauma : Haemorrhage ✅
  • Trauma Physiology
  • Trauma: Cardiac Arrest
  • Trauma: Epilepsy - Post Traumatic
  • Trauma: Flail Chest Rib fractures
  • Trauma: Initial Assessment and Management
  • Trauma: Post traumatic stress disorder
  • Trauma: Resuscitative Thoracotomy
  • Trauma: Silver Trauma in older patients
  • Trauma: Spinal Injury
  • Trauma: Thoracic Assessment and Management
  • Trauma:Prehospital
  • Traumatic Auricular Haematoma (Cauliflower ear)
  • Travel health advice
  • Travellers Diarrhoea
  • Trazodone 💊
  • Treatment Escalation Plans (TEP) in the Elderly
  • Treponema
  • Tretinoin (All-trans-retinoic acid (ATRA) )
  • Triangles of the neck
  • Trichinellosis
  • Trichomoniasis Vaginalis ✅
  • Tricuspid Atresia
  • Tricuspid Regurgitation
  • Tricuspid Stenosis ❤️
  • Tricyclic Antidepressant Toxicity
  • Tricyclic antidepressants
  • Trigeminal Nerve (Vth Nerve)
  • Trigeminal Neuralgia
  • Trihexyphenidyl (benzhexol)
  • Trimethoprim 💊
  • Trinucleotide (triplet) Repeat Disorders
  • Trochlear Nerve (VIth nerve)
  • Tropheryma whipplei (Whipple disease)
  • Tropical Sprue
  • Truncus Arteriosus (Children) ❤️
  • Tuberculosis
  • Tuberculous Meningitis
  • Tuberous sclerosis
  • Tularaemia (Francisella tularensis)
  • Tumour Lysis Syndrome
  • Tumour Necrosis Factor
  • Tumour Suppressor Genes
  • Tumour markers
  • Turcot's syndrome (Brain tumor polyposis syndrome)
  • Turners syndrome (Children)
  • Twins
  • Tympanic (Eardrum) membrane perforation
  • Types of Hypersensitivity Reactions
  • Types of Joints
  • Types of Organ Transplant Rejection
  • Tyrosine Kinase receptors
  • USMLE High Yield
  • USMLE Lab Values
  • Ubiquitin
  • Ulcerative Colitis ✅
  • Ulnar nerve
  • Ultrasound Physics & Imaging
  • Undifferentiated Inflammatory Arthritis (Children)
  • Unintentional weight loss (Adults)
  • Unprotected Sex and Emergency Contraception (EC)
  • Unsteadiness
  • Unwanted pregnancy and termination
  • Upper Gastrointestinal Bleed ✅
  • Upper Limb fractures and injuries
  • Upper and Lower Limb Neurology (OSCE)
  • Upper and Lower Motor Neuron signs
  • Upper limb Soft Tissue Injuries
  • Upper respiratory tract infection
  • Urea Cycle defects
  • Urethral Discharge (Urethritis)
  • Urethral syndrome
  • Urinary Catheterisation
  • Urinary Incontinence ✅
  • Urinary Obstruction
  • Urinary Tract Infection (UTI Children)
  • Urinary Tract Obstruction
  • Urinary symptoms
  • Urothelial carcinoma (Bladder cancer plus others) ✅
  • Urticaria
  • Usher syndrome
  • Uterine fibroids
  • Uveitis ✅
  • VIPomas
  • VTE Prophlyaxis✅
  • Vaccine in Older Patients
  • Vaginal Candidiasis
  • Vaginal Carcinoma
  • Vaginal Prolapse
  • Vagus Nerve (Cranial Nerve X)
  • Valaciclovir 💊
  • Valsartan 💊
  • Vancomycin 💊
  • Variable rate intravenous insulin infusion VRIII 💊
  • Variant (Prinzmetal) Angina
  • Variant Creutzfeldt Jakob disease
  • Varicella Cerebral Vasculopathy
  • Varicose veins ✅
  • Variegate Porphyria
  • Vasa Praevia
  • Vascular Dementia
  • Vascular Surgery: Introduction
  • Vascular access for haemodialysis
  • Vasculitis - General Issues and Classification
  • Vasopressin (AVP) Antidiuretic hormone
  • Vasovagal syncope (OSCE focused)
  • Vaughan-Williams Classification
  • Vecuronium 💊
  • Vedolizumab (Entyvio)
  • Venepuncture (Blood tests)
  • Venlafaxine 💊
  • Venous Insufficiency and Leg Ulcers
  • Venous Supply of the leg
  • Venous Thromboembolism Pregnancy and Puerperium
  • Venous access Cannulas OSCE
  • Venous and Arterial Ulcers and Other Lower Limb Ulcers
  • Venous and Arterial and Pressure Ulcers
  • Ventilator associated pneumonia (VAP)
  • Ventricular Fibrillation
  • Ventricular Septal defect (VSD) ❤️
  • Ventricular Tachycardia VT ✅
  • Ventricular ectopic beats
  • Verapamil 💊
  • Vertebral artery dissection
  • Vesicoureteric reflux (VUR) (Children)
  • Vestibulocochlear Nerve (Cranial Nerve VIII)
  • Vexas Syndrome
  • Vibrio parahaemolyticus
  • Vibrio vulnificus
  • Vibrio vulnificus
  • Vigabatrin (Sabril) 💊
  • Vinblastine
  • Vincent's angina
  • Vincristine
  • Violence Aggression and Conflict Resolution
  • Viral Gastroenteritis and other causes
  • Viral Haemorrhagic Fevers (VHF)
  • Viral Meningitis
  • Viral exanthema ✅
  • Viral hepatitides
  • Viruses and their infections
  • Visual Basic Programming
  • Visual Hallucinations in the elderly
  • Visual acuity
  • Vitamin A Deficiency
  • Vitamin B1 Thiamine deficiency
  • Vitamin B12 deficiency
  • Vitamin B12 excess
  • Vitamin C deficiency (Scurvy)
  • Vitamin D (1,25 OH2)
  • Vitamin D 25 (OH) D Testing
  • Vitamin D Physiology
  • Vitamin D Replacement
  • Vitamin D resistant rickets (Children)
  • Vitamin K (Phytomenadione)
  • Vitamin K deficiency
  • Vitiligo
  • Vocal Cord Dysfunction / Inducible Laryngeal Obstruction (ILO) ✅
  • Voltarol (Diclofenac)
  • Volvulus (Children)
  • Vomiting
  • Von Gierke Disease (Children)
  • Von Hippel Lindau
  • Von Willebrand Disease
  • Vulval itching and lesions
  • Vulval/vaginal lump
  • Waardenburg's syndrome
  • Waldenstrom Macroglobulinaemia
  • Warfarin 💊
  • Water Physiology
  • Waterlow pressure ulcer risk assessment score
  • Watershed Infarcts
  • Waveform CO₂ capnography
  • Weakness in Adults – Causes, Features, and Diagnosis 🧑‍⚕️
  • Weight Gain Adults
  • Wellbeing Checks in General Practice for GPs
  • Wellens Syndrome
  • Werdnig–Hoffman Disease (Spinal Muscular Atrophy Type 1)
  • Wernicke Korsakoff Syndrome
  • Wheeze: Clinical Approach and Considerations
  • White Blood Cells
  • Williams Syndrome (Children)
  • Wilson disease
  • Windows Powershell
  • Wiskott-Aldrich syndrome (Children)
  • Wolff-Parkinson White syndrome (WPW) AVRT ✅
  • Wolfram syndrome (DIDMOAD)
  • Wound Management
  • Wound healing
  • Wrist Injury: Smith’s Fracture
  • Wrist Joint Structure and Form
  • X linked Agammaglobulinaemia (Bruton)
  • X linked Hypophosphataemic rickets ✅
  • X-Linked Recessive Inheritance
  • X-linked Ichthyosis
  • X-linked lymphoproliferative disease (Children)
  • Xanthelasma ✅
  • Xanthochromia
  • Xeroderma pigmentosum
  • Yaws (Frambesia) Treponema pertenue
  • Yellow Fever
  • Yellow Nail Syndrome
  • Yersinia enterocolitica
  • Yersinia pestis - Bubonic Plague
  • Yersinia pseudotuberculosis
  • Young Mania Rating Scale
  • ZZ_Abnormal char
  • Zidovudine (Retrovir) AZT - ZDV 💊
  • Zieve's syndrome
  • Zika virus
  • Zinc deficiency
  • Zolbetuximab (Vyloy)
  • Zoledronic acid (Zoledronate) 💊
  • Zollinger Ellison syndrome
  • Zolpidem 💊
  • Zopiclone 💊
  • eGFR
  • intedanib (Ofev®) 💊
  • zNecrobiosis
  • ❤️ Peripartum cardiomyopathy ✅
  • ️Causes of a Limp in Adults
  • 🍽️ Malnutrition in Children
  • 💓Atrial Fibrillation (AF)✅
  • 💓Atrial flutter ✅
  • 📊 Thromboelastography (TEG)
  • 🔄 ROTEM - Rotational Thromboelastometry
  • 🩺 Complex Regional Pain Syndrome (CRPS)
  • 🩺 Urinary Tract Infection (UTI) (OSCE focused)
  • Download the amazing global Makindo app: ✅ Means NICE/National Guidelines 2026 compliant Android | Apple
    MEDICAL DISCLAIMER: Educational use only. Not for diagnosis or management. See below for full disclaimer.

    Surgery: Cardiothoracic, neurosurgery and plastic surgery

    🩺 Cardiothoracic, neurosurgery and plastic surgery — page 11 (the last) of the Surgery chapter. These are specialist areas, but every doctor meets their patients — on the ward after heart surgery, in ED with a sudden headache, or with a wound that won't heal. Focus on who to refer, how urgently, and what can go wrong afterwards. The medical side of heart disease, stroke and skin cancer is in the Cardiology, Neurology and Dermatology chapters.
    Your four questions for every patient: Is there an emergency (tamponade, raised intracranial pressure, a failing flap, necrotising infection)? Which specialist needs to know — and how fast? What complications are typical of this operation? What does the patient need for recovery — rehabilitation, wound care, driving advice, medicines?


    Coronary Artery Bypass Grafting
    • CABG — bypasses narrowed coronary arteries using grafts:
      • Left internal mammary (thoracic) artery to the left anterior descending — the best graft (over 90% open at 10 years).
      • Great saphenous vein grafts (less durable), radial artery grafts.
      • Usually through a median sternotomy with cardiopulmonary bypass ("on-pump"); "off-pump" in some.
    • CABG rather than PCI (stents) is generally preferred for (heart team decision):
      • Left main stem disease.
      • Three-vessel disease, especially with diabetes or reduced LV function.
      • Complex anatomy (high SYNTAX score).
    • Before surgery — stop P2Y12 inhibitors (clopidogrel and ticagrelor 5 days, prasugrel 7 days) where possible; usually continue aspirin; stop DOACs; optimise anaemia, diabetes and smoking; dental check before valve surgery.
    • Risk assessment — EuroSCORE II estimates operative mortality.
    • Outcomes — relieves angina and improves survival in high-risk anatomy; secondary prevention continues for life (aspirin, statin, BP control, cardiac rehabilitation).
    Valve Surgery
    • Aortic stenosis — intervene when severe and symptomatic (angina, syncope, breathlessness), or severe with reduced LV function:
      • Surgical aortic valve replacement (SAVR) — younger, lower-risk patients, or those needing other cardiac surgery.
      • TAVI (transcatheter aortic valve implantation, usually via the femoral artery) — older or higher-risk patients; increasingly used at lower risk too (heart team decision). Risks — stroke, vascular injury, heart block (pacemaker), paravalvular leak.
    • Mitral regurgitation — repair is preferred to replacement where possible (degenerative disease); transcatheter edge-to-edge repair (TEER, e.g. MitraClip) for high-risk patients.
    • Mitral stenosis (usually rheumatic) — balloon valvotomy if anatomy suits; otherwise replacement.
    • Valve types:
      ValvePros and consAnticoagulation
      MechanicalLasts a lifetime; audible click; younger patientsLifelong warfarin (target INR depends on valve and site — often 2.5–3.5); DOACs are contraindicated
      Biological (tissue)Wears out after 10–20 years (faster in the young); older patients or those who can't take warfarin; may later have valve-in-valve TAVIAspirin (± warfarin for about 3 months after surgery)
    • Prosthetic valve complications — endocarditis (fever in anyone with a prosthetic valve — blood cultures and echo), valve thrombosis (mechanical, poor INR control — breathlessness, loss of click, emboli), haemolysis, paravalvular leak, bleeding from anticoagulation.
    • Endocarditis surgery — heart failure from valve destruction, uncontrolled infection (abscess), large vegetations with embolism, prosthetic valve infection.
    After Cardiac Surgery
    ComplicationFeaturesManagement
    BleedingHigh chest drain output, falling Hb, shockCorrect clotting (point-of-care tests), blood products; re-exploration if heavy or continuing
    Cardiac tamponadeLow BP, rising CVP, falling urine output, sudden drop in drain output (clot), equalising pressures; can be late (days)Echo; urgent re-sternotomy (may be done at the bedside in arrest — Cardiac Surgical Advanced Life Support)
    Atrial fibrillationVery common (about 30%), days 2–4Correct potassium and magnesium, beta-blocker or amiodarone, anticoagulate if persistent
    Low cardiac outputLow BP, cool peripheries, low urine output, high lactateInotropes, pacing (epicardial wires), balloon pump
    Heart blockEspecially after valve surgery and TAVITemporary epicardial pacing; permanent pacemaker if persists
    Stroke and deliriumEmbolism, low perfusionImaging, stroke team; delirium care
    AKIBypass, low output, contrast, drugsFluids, avoid nephrotoxins, renal replacement if needed
    Sternal wound infection and mediastinitisWound discharge, a clicking, unstable sternum, fever (days to weeks); diabetes, obesity, bilateral mammary graftsCultures, antibiotics, debridement, rewiring, flap cover
    Post-pericardiotomy syndromeWeeks later — fever, pleuritic chest pain, pericardial rub, effusionNSAIDs or colchicine; watch for tamponade
    Leg wound problemsVein harvest site infection or swellingWound care, antibiotics
    • Cardiac arrest after cardiac surgery (CALS protocol) — for VF or pulseless VT, give up to three stacked shocks before chest compressions; for asystole or severe bradycardia — pace via epicardial wires; emergency resternotomy within about 5 minutes if no response (tamponade or bleeding).
    • Recovery — sternal precautions (no heavy lifting or pushing for about 6–12 weeks), cardiac rehabilitation, no driving for about 4 weeks after CABG (car licence; DVLA — longer for HGV), return to work around 6–12 weeks.
    Aortic Surgery
    • Type A aortic dissection (involves the ascending aorta) — emergency surgery (replacement of the ascending aorta ± arch); mortality without surgery rises about 1–2% per hour in the first day.
      • Presentation — sudden tearing chest pain radiating to the back, BP difference between arms, pulse deficits, new aortic regurgitation murmur, stroke, MI (right coronary), tamponade.
      • CT angiography; control BP and heart rate (IV labetalol) while arranging surgery; avoid thrombolysis (may be mistaken for MI).
    • Type B dissection — medical BP control; TEVAR for complications (see the Vascular Surgery page).
    • Thoracic aortic aneurysm — often Marfan syndrome, bicuspid aortic valve, Loeys–Dietz, Ehlers–Danlos type IV, hypertension; elective surgery at about 5.5 cm (lower — about 4.5–5.0 cm — in Marfan and bicuspid valves with risk factors); family screening; BP control (beta-blockers or ARBs).
    • Aortic root replacement — Bentall procedure (valve and root) or valve-sparing (David procedure).
    • Complications — bleeding, stroke, spinal cord ischaemia (paraplegia — descending aorta surgery; CSF drainage reduces risk), kidney failure.
    Lung Cancer Surgery
    • Surgery offers the best chance of cure for early-stage non-small cell lung cancer (stage I–II and selected stage III).
    • Fitness for surgery:
      • Lung function — FEV1 and TLCO (gas transfer); predicted post-operative values (based on segments removed); cardiopulmonary exercise testing or shuttle walk test if borderline.
      • Cardiac risk — ECG, history, echo if needed.
      • Performance status, frailty, smoking (stop beforehand — prehabilitation).
    • Staging before surgery — PET-CT; EBUS (endobronchial ultrasound) node sampling for enlarged or PET-positive mediastinal nodes; brain MRI for higher stages.
    • Operations:
      • Lobectomy — standard (often by VATS — video-assisted thoracoscopic surgery — or robotic).
      • Segmentectomy or wedge resection — small tumours or limited lung function.
      • Pneumonectomy — central tumours; highest risk.
    • Not fit for surgery — stereotactic ablative radiotherapy (SABR) for early tumours.
    • After surgery — adjuvant chemotherapy (stage II–III), targeted treatment (e.g. osimertinib for EGFR mutations), or immunotherapy; neoadjuvant chemo-immunotherapy in some.
    • Complications — prolonged air leak, pneumonia, AF, bronchopleural fistula (after pneumonectomy — sudden coughing up of fluid, falling fluid level), empyema, post-thoracotomy pain, respiratory failure.
    • Other thoracic surgery — lung metastasectomy, lung volume reduction or endobronchial valves for severe emphysema, thymectomy (myasthenia gravis, thymoma), mesothelioma (mostly non-surgical), lung transplantation.
    Pneumothorax, Empyema and Chest Drains
    • Surgery for pneumothorax (BTS 2023) — persistent air leak (usually over 3–5 days), recurrent pneumothorax (including the first contralateral one), bilateral pneumothorax, haemopneumothorax, and high-risk occupations (pilots, divers):
      • VATS bullectomy and pleurodesis (pleurectomy or abrasion) — low recurrence.
      • Medical pleurodesis (talc via a drain) for people unfit for surgery.
    • Empyema (pus in the pleural space) — pleural fluid pH under 7.2, frank pus, or organisms on Gram stain:
      • Chest drain plus antibiotics; intrapleural tPA and DNase (MIST2) for poorly draining collections.
      • Surgery (VATS or open decortication) if drainage and fibrinolytics fail — refer early (within about 5–7 days of non-response).
    • Chest drains:
      • Safe triangle — the lateral edge of pectoralis major, the lateral edge of latissimus dorsi, a line level with the nipple (5th intercostal space), and the axilla at the apex.
      • Insert just above the rib (the neurovascular bundle runs below each rib); ultrasound guidance for fluid (BTS).
      • Swinging (fluid moving with breathing) means the drain is in the pleural space; bubbling means an ongoing air leak.
      • Never clamp a bubbling drain (risk of tension pneumothorax); keep the bottle below the chest.
      • Re-expansion pulmonary oedema — draining a large effusion too fast (limit to about 1.5 L at once).
    • Indwelling pleural catheters — for recurrent malignant effusions (drained at home).
    Raised Intracranial Pressure and Hydrocephalus
    • The skull is a fixed box — brain, blood and CSF; if one increases (tumour, bleed, swelling, blocked CSF), pressure rises (Monro–Kellie doctrine).
    • Features of raised ICP — headache (worse lying down and in the morning, worse with coughing or straining), vomiting, papilloedema, falling GCS, third nerve palsy (dilated pupil — uncal herniation), sixth nerve palsy (a false localising sign), Cushing's response (high BP, slow pulse, irregular breathing — late).
    • Emergency management — head up 30°, protect the airway (intubate if GCS 8 or less), normal CO2, hypertonic saline or mannitol, dexamethasone for tumour swelling (not for trauma or stroke), urgent neurosurgery.
    • Hydrocephalus:
      • Obstructive (non-communicating) — blockage within the ventricles (tumours, aqueduct stenosis, posterior fossa bleeds).
      • Communicating — poor CSF absorption (after subarachnoid haemorrhage, meningitis).
      • Treatment — external ventricular drain (EVD — emergency), ventriculoperitoneal (VP) shunt, or endoscopic third ventriculostomy.
    • Normal pressure hydrocephalus — older people with the triad of gait disturbance (magnetic, shuffling — usually first), urinary incontinence and dementia ("wet, wobbly and wacky"); enlarged ventricles on CT; lumbar drain or tap test, then VP shunt.
    • Shunt problems:
      • Blockage — headache, vomiting, drowsiness, symptoms like those before the shunt — urgent neurosurgical review (CT and shunt series X-rays).
      • Infection — fever, wound redness, abdominal pain (peritoneal end) — usually within months of surgery (staphylococci).
      • Over-drainage (headache on standing, subdural collections).
    • Idiopathic intracranial hypertension — young obese women, headache, papilloedema, normal imaging, high opening pressure; weight loss, acetazolamide; shunt or optic nerve sheath fenestration if vision is threatened.
    Subarachnoid Haemorrhage and Vascular Lesions
    • Subarachnoid haemorrhage — most non-traumatic cases from a ruptured berry aneurysm (circle of Willis):
      • Thunderclap headache (worst ever, maximal within 1 minute), vomiting, neck stiffness, photophobia, collapse, seizures, reduced consciousness.
      • CT head — very sensitive within 6 hours; if negative and done after 6 hours — lumbar puncture at least 12 hours after onset (xanthochromia).
      • CT angiography to find the aneurysm.
    • Management:
      • Urgent transfer to a neurosurgical centre.
      • Secure the aneurysm — endovascular coiling (preferred for most — ISAT trial) or surgical clipping — ideally within 24–48 hours.
      • Nimodipine 60 mg every 4 hours for 21 days — reduces delayed cerebral ischaemia (vasospasm).
      • BP control before the aneurysm is secured; analgesia; antiemetics; VTE prevention with stockings or pneumatic devices.
    • Complications:
      • Rebleeding — highest in the first 24 hours.
      • Hydrocephalus — drowsiness — EVD.
      • Delayed cerebral ischaemia (vasospasm) — days 4–14 — new deficit or drowsiness — keep euvolaemic; endovascular treatment.
      • Hyponatraemia — SIADH or cerebral salt wasting (low volume) — don't fluid restrict.
      • Seizures, cardiac changes (stunned myocardium, arrhythmias).
    • Associations of berry aneurysms — adult polycystic kidney disease, coarctation of the aorta, Ehlers–Danlos syndrome, smoking, hypertension, family history (screening for those with 2 or more affected first-degree relatives).
    • Unruptured aneurysms — treat or watch depending on size, site, and patient factors.
    • Arteriovenous malformations — younger people; haemorrhage or seizures; surgery, embolisation or stereotactic radiosurgery.
    • Cavernomas — seizures, small bleeds; often watched.
    Brain Tumour Surgery
    • Presentation — progressive neurological deficit, new seizures in an adult, headache with features of raised ICP, personality or cognitive change.
    • Referral (NICE NG12) — progressive, sub-acute loss of central nervous function → direct-access MRI (or urgent referral); new focal seizures → urgent assessment.
    • Common tumours:
      • Metastases — the commonest (lung, breast, melanoma, kidney, colorectal); surgery or stereotactic radiosurgery for one or a few lesions.
      • Glioblastoma — the commonest primary malignant tumour in adults; maximal safe resection, then radiotherapy with temozolomide (Stupp protocol); poor prognosis (median survival about 15 months).
      • Low-grade gliomas — younger adults with seizures; IDH status guides prognosis.
      • Meningioma — benign, extra-axial, women; often found by chance; surgery, radiotherapy or watching.
      • Pituitary adenoma — bitemporal hemianopia, hormone excess or deficiency; trans-sphenoidal surgery (except prolactinomas — dopamine agonists first); risks — CSF leak, diabetes insipidus, hypopituitarism (steroid cover).
      • Vestibular schwannoma (acoustic neuroma) — one-sided hearing loss and tinnitus; bilateral in NF2; watch, radiosurgery or surgery (facial nerve risk).
      • Children — posterior fossa tumours (medulloblastoma, pilocytic astrocytoma, ependymoma) — headache, vomiting, ataxia, hydrocephalus.
    • Peri-operative care — dexamethasone for oedema (with a PPI, monitor glucose), seizure prophylaxis or treatment (levetiracetam), awake craniotomy for tumours near speech or motor areas, 5-ALA fluorescence-guided surgery, VTE prophylaxis.
    • Driving — DVLA rules depend on tumour type and seizures — patients must be told to stop driving and inform the DVLA (see the Neurology chapters).
    Degenerative Spinal Surgery
    • Lumbar disc prolapse — sciatica; most settle within 6–12 weeks; microdiscectomy for persistent severe pain, progressive weakness or cauda equina syndrome (emergency).
    • Lumbar spinal stenosis — neurogenic claudication; decompression (laminectomy) for severe cases.
    • Degenerative cervical myelopathy — the commonest cause of spinal cord problems in adults (often missed):
      • Clumsy hands (dropping things, difficulty with buttons), unsteady gait, numbness, neck pain, later bladder problems.
      • Signs — upper motor neurone signs (hyper-reflexia, Hoffmann's sign, upgoing plantars, clonus), wasting of the small hand muscles.
      • MRI of the cervical spine; refer to spinal surgery; decompression stops progression (moderate to severe or progressive disease).
    • Cervical radiculopathy — arm pain in a nerve root distribution (C6 — thumb, C7 — middle finger); most settle; surgery (ACDF — anterior cervical discectomy and fusion) if persistent or weak.
    • Spondylolisthesis — one vertebra slips forward on another (L5/S1 in young athletes; L4/5 degenerative); fusion if severe.
    • Complications of spinal surgery — dural tear (CSF leak, headache on standing), nerve root injury, infection (discitis), haematoma (new weakness — emergency), recurrent disc prolapse, adjacent segment disease.
    Neurosurgical Infections and CSF Leaks
    • Brain abscess — from sinus, ear or dental infection, endocarditis, cyanotic heart disease, penetrating injury, or immunosuppression:
      • Headache, fever (not always), focal signs, seizures, raised ICP.
      • CT or MRI — ring-enhancing lesion (differential — tumour, toxoplasmosis in HIV).
      • Aspiration or excision plus prolonged IV antibiotics (e.g. ceftriaxone and metronidazole); find the source. Don't do an LP (risk of coning).
    • Subdural empyema — rapid deterioration after sinusitis; emergency drainage.
    • Spinal epidural abscess — back pain, fever, then neurological deficit; IV drug use, diabetes; urgent MRI, antibiotics ± surgical decompression.
    • Post-operative infections — wound infection, bone flap infection, shunt and EVD infections (meningitis — CSF sampling from the device).
    • CSF leaks:
      • CSF rhinorrhoea (clear watery fluid from the nose — test for beta-2 transferrin) after skull base fractures or pituitary surgery; CSF otorrhoea after temporal bone fractures.
      • Risk of meningitis — pneumococcal vaccination; most traumatic leaks stop in days; surgical repair if persistent.
      • Spontaneous intracranial hypotension — headache on standing, relieved by lying flat; MRI; epidural blood patch.
    Wound Healing and the Reconstructive Ladder
    • Phases of healing — haemostasis (minutes), inflammation (days 1–5), proliferation (granulation tissue, new vessels, collagen — days 3 to 3 weeks), remodelling (weeks to over a year; scar strength reaches about 80% of normal skin).
    • Primary intention — wound edges brought together (sutures, glue, staples) — fast, neat scar; secondary intention — left open to heal from the base (contaminated wounds, abscess cavities, pilonidal wounds); delayed primary closure — closed after a few days once clean.
    • Factors that slow healing — infection, poor blood supply, smoking, diabetes, malnutrition (protein, vitamin C, zinc), steroids, chemotherapy, radiotherapy, tension, foreign bodies, older age, obesity.
    • Laceration care — clean and irrigate, explore for foreign bodies and tendon or nerve injuries, close within about 6–8 hours (longer for the face with good blood supply); tetanus; antibiotics for bites and contaminated wounds.
    • Suture removal times (approximate) — face 5 days, scalp 7 days, trunk and arms 7–10 days, legs and back 10–14 days, over joints 14 days.
    • The reconstructive ladder — choose the simplest method that will work:
      1. Healing by secondary intention (± negative pressure wound therapy).
      2. Direct (primary) closure.
      3. Skin graft.
      4. Local flap.
      5. Regional (pedicled) flap.
      6. Free flap (microvascular).
    • Negative pressure wound therapy ("VAC") — suction dressing that removes fluid and encourages granulation; used for open abdomens, large wounds, before grafting.
    Skin Grafts and Flaps
    TypeDescriptionPoints
    Split-thickness skin graftEpidermis plus part of the dermis, taken with a dermatome (usually from the thigh); can be meshed to cover more areaTakes well; donor site heals by itself (like a graze); contracts more; poorer cosmetic result; used for burns and large wounds
    Full-thickness skin graftWhole dermis (from behind the ear, above the clavicle, groin); donor site closed directlyBetter colour and texture, contracts less; small areas — face, hands
    Local flapNearby tissue moved with its own blood supply (rotation, advancement, transposition)Good match; face and skin cancer defects
    Pedicled flapTissue moved on its named blood vessel (e.g. latissimus dorsi, pectoralis major)Bigger defects; breast and chest wall reconstruction
    Free flapTissue detached and its vessels joined to new vessels under the microscope (e.g. DIEP, anterolateral thigh, radial forearm)Complex reconstruction; open fractures, head and neck cancer, breast
    • Grafts need a vascular bed — they take on granulation tissue, muscle and fascia; they won't take on bare bone (without periosteum), bare tendon (without paratenon), cartilage, infected wounds (especially beta-haemolytic streptococcus), or irradiated tissue.
    • Graft failure — commonest causes: haematoma or seroma under the graft, shearing (movement), infection.
    • Flap monitoring — colour, temperature, capillary refill, Doppler signal (hourly at first):
      • Venous congestion (commonest) — purple, swollen, brisk refill, dark bleeding on pinprick.
      • Arterial insufficiency — pale, cold, slow or no refill, no bleeding on pinprick.
      • A failing free flap is an emergency — return to theatre quickly (salvage is possible within hours); keep the patient warm, well filled, and avoid vasoconstrictors and tight dressings.
    Skin Cancer Surgery
    • Basal cell carcinoma — pearly, rolled edge, telangiectasia, slow growing, rarely spreads; surgical excision with a 4 mm margin for small well-defined lesions; Mohs micrographic surgery for high-risk sites (central face, around the eyes, nose, lips, ears), recurrent or poorly defined tumours; other options — curettage, cryotherapy, topical treatments, radiotherapy.
    • Squamous cell carcinoma — a growing, keratinising, tender nodule or ulcer on sun-damaged skin (also in old scars — Marjolin's ulcer; transplant recipients); excision with 4–6 mm margins (wider for high-risk); can spread to lymph nodes — examine nodes; suspected cancer pathway referral.
    • Melanoma:
      • Use the ABCDE or weighted 7-point checklist (major — change in size, shape, colour; minor — diameter 7 mm or more, inflammation, oozing, change in sensation).
      • Excision biopsy with a 2 mm margin first (don't shave or partly biopsy suspicious lesions).
      • Then wide local excision based on Breslow thickness — in situ: 0.5–1 cm; up to 1 mm thick: 1 cm; 1–4 mm: 1–2 cm; over 4 mm: 2–3 cm (follow current NICE NG14 and BAD guidance).
      • Sentinel lymph node biopsy for stage IB and above (staging, not treatment); adjuvant immunotherapy for higher-risk disease.
    • Refer — melanoma and SCC on the suspected cancer pathway; BCCs routinely unless in a high-risk site or large (see the Skin Lesions and Cancer chapter).
    • Other skin lumps — lipomas (soft, mobile — excise if over 5 cm, deep, growing or painful — consider sarcoma), epidermoid cysts (punctum — excise when not inflamed), keratoacanthoma (fast-growing crater with keratin plug — excise, may be SCC).
    Pressure Ulcers
    • Damage to skin and underlying tissue from pressure, shear and friction — usually over bony areas (sacrum, heels, hips, ischial tuberosities, back of the head in infants).
    • Risk factors — immobility, spinal cord injury, older age, malnutrition, incontinence (moisture), poor circulation, diabetes, sedation, delirium, devices (masks, catheters, casts).
    • Risk assessment — validated tools (e.g. Waterlow, Braden, Purpose-T) on admission; skin checks.
    • Categories (NPUAP/EPUAP):
      • 1 — non-blanching redness of intact skin.
      • 2 — partial-thickness skin loss (shallow ulcer or blister).
      • 3 — full-thickness skin loss (fat visible, no bone, tendon or muscle).
      • 4 — full-thickness tissue loss with exposed bone, tendon or muscle.
      • Unstageable (base covered by slough or eschar) and deep tissue injury (purple or maroon intact skin).
    • Prevention and treatment (NICE CG179) — repositioning (at least every 6 hours for adults at risk, every 4 hours at high risk), pressure-relieving mattresses and heel offloading, skin care and moisture management, nutrition and hydration, treat infection (osteomyelitis under deep ulcers — MRI), debridement; plastic surgery flap reconstruction for selected category 3–4 ulcers.
    • Safeguarding — category 3 and 4 ulcers (and some category 2) may need reporting under local safeguarding and patient safety processes.
    Necrotising Soft Tissue Infection
    • Necrotising fasciitis — a rapidly spreading infection of the fascia and soft tissues — a surgical emergency (mortality about 20–30%).
    • Types:
      • Type 1 (polymicrobial) — mixed aerobes and anaerobes — older people, diabetes, after surgery; includes Fournier's gangrene (perineum).
      • Type 2 (monomicrobial) — group A streptococcus (± staphylococcus) — healthy people after minor injuries, IV drug users, chickenpox in children; toxic shock.
      • Gas gangrene (clostridial myonecrosis) — deep contaminated wounds; crepitus, bronze skin.
    • Early features — pain out of proportion to the visible signs, rapid spread, tense swelling beyond the redness, high fever, tachycardia; looks like cellulitis but the patient is much sicker.
    • Later features — dusky or purple skin, blisters (haemorrhagic bullae), crepitus, skin numbness, necrosis, shock and multi-organ failure.
    • LRINEC score (CRP, WCC, Hb, sodium, creatinine, glucose) may help — but a low score doesn't exclude it; clinical suspicion is key.
    • Management:
      • Urgent surgical debridement — the most important treatment; "dishwater" fluid and fascia that separates easily ("finger test"); repeat debridement every 24–48 hours.
      • Broad-spectrum IV antibiotics including clindamycin (stops toxin production) — e.g. piperacillin–tazobactam (or meropenem) with clindamycin per local policy; IVIG in streptococcal toxic shock (specialist).
      • Don't delay surgery for imaging; ICU care; later reconstruction (grafts and flaps).
      • Group A streptococcus — notify UKHSA; close contacts may need prophylaxis.
    Scars, Keloids and Cleft Lip and Palate
    • Hypertrophic scars — raised, red, stay within the wound edges; appear within weeks; often improve over 1–2 years; burns, wounds under tension, infection.
    • Keloid scars — grow beyond the wound edges, may appear months later, rarely regress; more common in darker skin and on the earlobes, chest, shoulders and upper back; often recur after excision.
    • Treatment of problem scars — silicone gel or sheets, pressure garments (burns), intralesional steroid (triamcinolone), laser, cryotherapy; keloid excision combined with steroid injection or radiotherapy (to reduce recurrence).
    • Scar contractures — tight scars across joints (burns) — Z-plasty, release and grafting, physiotherapy and splints.
    • Langer's lines (skin tension lines) — incisions along them heal with neater scars.
    • Cleft lip and palate:
      • One of the commonest birth differences (about 1 in 700 UK births); cleft lip ± palate, or isolated cleft palate (more associated with syndromes, e.g. 22q11 deletion, Pierre Robin sequence).
      • Risk factors — family history, maternal smoking, anticonvulsants (phenytoin, valproate), folate deficiency.
      • Problems — feeding (specialist bottles and teats; isolated cleft palate can be missed — examine the palate in every newborn), speech, hearing (glue ear — grommets), dental problems, appearance and psychological impact.
      • Care — a regional cleft team; lip repair at about 3 months; palate repair by about 6–12 months; speech therapy, alveolar bone grafting (age 8–11), orthodontics and later surgery.
    Specialist Surgery at a Glance
    ConditionKey cluesManagement
    Left main stem or 3-vessel disease with diabetesAngiography findingsCABG (heart team)
    Severe symptomatic aortic stenosisSyncope, angina, breathlessnessSAVR or TAVI
    Tamponade after cardiac surgeryLow BP, rising CVP, drain output stopsEcho, urgent resternotomy
    Mechanical valveMetallic clickLifelong warfarin — no DOACs
    Type A dissectionTearing chest pain to the back, arm BP differenceCT angiography, emergency surgery
    Early lung cancer, fitStage I–II NSCLC, adequate FEV1 and TLCOLobectomy (VATS); SABR if unfit
    EmpyemaPleural pH under 7.2, pusChest drain, antibiotics, tPA/DNase, surgery if failing
    Subarachnoid haemorrhageThunderclap headache, CT or xanthochromiaCTA, coiling or clipping, nimodipine
    Normal pressure hydrocephalusGait, incontinence, dementiaTap test, VP shunt
    Blocked VP shuntHeadache, vomiting, drowsinessUrgent neurosurgical review
    Degenerative cervical myelopathyClumsy hands, unsteady gait, UMN signsMRI, decompression
    Brain abscessFever, focal signs, ring-enhancing lesionAspiration, IV antibiotics, no LP
    Failing flap — venousPurple, swollen, brisk refillReturn to theatre
    Necrotising fasciitisPain out of proportion, rapid spreadUrgent debridement, antibiotics with clindamycin
    KeloidScar growing beyond the wound edgeSilicone, steroid injection
    Spot the Diagnosis
    ClueDiagnosis
    Best long-term coronary graftLeft internal mammary artery to LAD
    Irregular pulse on day 3 after CABGPost-operative atrial fibrillation
    Falling BP, rising CVP and sudden drop in drain output 6 hours after cardiac surgeryCardiac tamponade
    Clicking, discharging sternum 2 weeks after CABGSternal wound infection or mediastinitis
    Fever, pleuritic pain and pericardial rub 3 weeks after cardiac surgeryPost-pericardiotomy syndrome
    Complete heart block after TAVIConduction injury — pacemaker
    Loss of valve click with breathlessness and a low INRMechanical valve thrombosis
    Tall man with a 4.8 cm aortic root and a family history of sudden deathMarfan syndrome — consider surgery
    Paraplegia after thoracoabdominal aneurysm repairSpinal cord ischaemia
    Coughing up large amounts of fluid a week after pneumonectomyBronchopleural fistula
    Second pneumothorax on the same side in a 24-year-oldRefer for VATS pleurodesis
    Breathlessness and pink frothy sputum after draining 3 L from the chestRe-expansion pulmonary oedema
    Dilated pupil and falling GCS with a growing tumourUncal herniation (third nerve)
    Shuffling gait, urinary incontinence and memory loss in a 75-year-oldNormal pressure hydrocephalus
    Headache, vomiting and drowsiness in a child with a VP shuntShunt blockage
    Thunderclap headache with xanthochromia at 12 hoursSubarachnoid haemorrhage
    New weakness on day 7 after SAH coilingDelayed cerebral ischaemia (vasospasm)
    Low sodium and low volume after SAHCerebral salt wasting — don't restrict fluids
    Berry aneurysm in a patient with enlarged cystic kidneysAdult polycystic kidney disease
    Polyuria with low urine osmolality after pituitary surgeryCranial diabetes insipidus
    One-sided hearing loss and tinnitus with a cerebellopontine angle massVestibular schwannoma
    Dropping things and positive Hoffmann's sign in a 65-year-oldDegenerative cervical myelopathy
    Ring-enhancing lesion after a dental abscessBrain abscess
    Clear nasal discharge positive for beta-2 transferrin after a head injuryCSF rhinorrhoea
    Skin graft lost over exposed tendon without paratenonPoor graft bed
    Purple, swollen free flap with brisk refillVenous congestion
    Pale, cold flap with no bleeding on pinprickArterial insufficiency
    Pearly nodule with rolled edges beside the noseBCC — consider Mohs surgery
    Growing ulcer in a 30-year-old burn scarMarjolin's ulcer (SCC)
    Purple intact skin over the sacrum of a bed-bound patientDeep tissue pressure injury
    Pain out of proportion with spreading redness and shock after a minor cutNecrotising fasciitis (group A strep)
    Scar spreading beyond the wound on the earlobe after piercingKeloid
    Milk coming out of the nose during feeds in a newbornCleft palate
    Exam-style Scenarios

    1. A 66-year-old man is on the cardiac ICU 5 hours after CABG. His BP has fallen from 120/70 to 80/50 over an hour, CVP has risen from 8 to 18 mmHg, and his chest drains, which were draining 150 mL an hour, have suddenly stopped.
    Answer: Cardiac tamponade (clotted drains).

    • Call the cardiac surgeon immediately; check drains for clot; bedside echo.
    • Fluids and inotropes as a temporary support; correct clotting; blood products.
    • Urgent re-sternotomy (in theatre, or at the bedside if he arrests — follow CALS).

    2. A 49-year-old woman has a sudden severe occipital headache while lifting shopping, "like being hit with a bat". She vomited and has neck stiffness. GCS 15. CT head at 3 hours shows blood in the basal cisterns.
    Answer: Subarachnoid haemorrhage.

    • CT angiography and urgent referral to the neurosurgical centre; analgesia, antiemetics, BP control (before the aneurysm is secured).
    • Nimodipine 60 mg every 4 hours for 21 days; keep euvolaemic; monitor sodium.
    • Endovascular coiling (or clipping) as soon as possible; watch for rebleeding, hydrocephalus and delayed cerebral ischaemia.

    3. A 72-year-old man has a year of increasingly clumsy hands — he can't do up buttons — and is unsteady when walking. He has brisk reflexes in all four limbs, positive Hoffmann's signs and wasting of the small muscles of the hands.
    Answer: Degenerative cervical myelopathy.

    • MRI cervical spine (cord compression, signal change).
    • Refer to spinal surgery — decompression (anterior or posterior) for moderate, severe or progressive myelopathy.
    • Advise avoiding neck manipulation; physiotherapy and falls prevention while waiting; recovery of lost function is limited — the aim is to stop progression.

    4. A 30-year-old man scratches his shin on a fence. Twenty-four hours later the leg is very painful and swollen with patchy redness and a purple blister. HR 130, BP 85/50, temperature 39.4°C. The pain is far worse than the appearance suggests.
    Answer: Necrotising fasciitis (probably group A streptococcus) with septic shock.

    • Sepsis Six; IV antibiotics including clindamycin (per local policy, e.g. with piperacillin–tazobactam or benzylpenicillin); resuscitation.
    • Emergency surgical debridement — don't wait for imaging or a scoring tool; repeat debridement in 24–48 hours.
    • ICU care; notify UKHSA (invasive group A strep); later reconstruction with skin grafts.

    5. A 58-year-old woman had a free flap breast reconstruction (DIEP) 8 hours ago. The nurse reports the flap has become purple and swollen; capillary refill is very brisk and a pinprick produces dark blood.
    Answer: Failing free flap from venous congestion.

    • Call the plastic surgeon immediately — return to theatre for exploration of the venous anastomosis (salvage is time-critical).
    • Meanwhile — loosen tight dressings or garments, check positioning (no pressure on the pedicle), keep the patient warm and well filled, avoid vasoconstrictors.
    • Check Hb and clotting; consider a haematoma compressing the vessels.
    Key Points
    • CABG is generally preferred to stents for left main stem and three-vessel disease, especially with diabetes.
    • Severe symptomatic aortic stenosis — SAVR or TAVI (heart team); TAVI can cause heart block.
    • Mechanical valves need lifelong warfarin — DOACs are contraindicated.
    • After cardiac surgery — AF is common; tamponade causes low BP, high CVP and a sudden drop in drain output.
    • Cardiac arrest after cardiac surgery — three stacked shocks, pacing, early resternotomy.
    • Type A dissection — emergency surgery; don't thrombolyse.
    • Lung cancer surgery needs FEV1, TLCO, PET-CT and EBUS; SABR if unfit.
    • Insert chest drains in the safe triangle above the rib; never clamp a bubbling drain.
    • Raised ICP — headache, vomiting, papilloedema, falling GCS; dexamethasone for tumour oedema only.
    • Normal pressure hydrocephalus — gait, incontinence, dementia; VP shunt.
    • Shunt patient with headache, vomiting or drowsiness — urgent neurosurgical review.
    • SAH — CT, then LP at 12 hours if needed; coiling; nimodipine for 21 days.
    • Degenerative cervical myelopathy — clumsy hands, gait problems, UMN signs — MRI and decompression.
    • Brain abscess — ring-enhancing lesion, aspirate, antibiotics, no LP.
    • Reconstructive ladder — simplest method that works; grafts need a vascular bed.
    • Free flap — purple and swollen is venous, pale and cold is arterial — return to theatre fast.
    • Melanoma — 2 mm margin excision biopsy, then wide excision by Breslow thickness.
    • Pressure ulcers — reposition, offload, nutrition; category 4 exposes bone, tendon or muscle.
    • Necrotising fasciitis — pain out of proportion; urgent debridement plus clindamycin.
    • Keloids grow beyond the wound edge; hypertrophic scars stay within it.
    Guidelines and Further Reading
    • ESC/EACTS: Guidelines on myocardial revascularisation; Guidelines for the management of valvular heart disease
    • NICE NG208: Heart valve disease presenting in adults
    • European Association for Cardio-Thoracic Surgery: Resuscitation after cardiac surgery (CALS)
    • DVLA: Assessing fitness to drive — cardiovascular and neurological disorders
    • NICE NG122: Lung cancer — diagnosis and management
    • British Thoracic Society: Pleural disease guideline (2023)
    • NICE NG228: Subarachnoid haemorrhage caused by a ruptured aneurysm
    • NICE NG99: Brain tumours (primary) and brain metastases in over 16s
    • Myelopathy.org and AO Spine: Guidelines for degenerative cervical myelopathy
    • NICE NG14: Melanoma — assessment and management; British Association of Dermatologists: BCC and cSCC guidelines
    • NICE CG179: Pressure ulcers — prevention and management
    • UKHSA: Management of invasive group A streptococcal infections
    • CLAPA and the Cleft Registry and Audit Network (CRANE)
    • BNF — for current doses

    Categories