Makindo Medical Notes"One small step for man, one large step for makindo" |
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Related Subjects: |Status Epilepticus (Epilepsy) |Coma management |Lorazepam |Phenytoin |Levetiracetam |Epilepsy - General Management |First Seizure |Epilepsy in Pregnancy |Febrile seizures
Name | Starting Dose | Frequency | Route |
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Levetiracetam (Epilepsy) | 250 mg OD for 1-2 weeks then 250 mg BD. Increasing dose every 2-4 weeks up to 1.5 g BD | BD | PO |
Levetiracetam (Status Epilepticus Loading) | Consider IV infusion of 50mg/kg over 15 minutes (max. 4500mg). [There is a wide variation in dosing from 40-60 mg/kg) | IV Infusion | IV |
Levetiracetam (Status Epilepticus Maintenance) | For eGFR 50mls-80mls/min - give 1000mg BD.
For eGFR 30mls-50mls/min - give 750mg BD. For eGFR <30mls/min - give 500mg BD. For dialysis patients - give 500mg OD | IV Infusion | IV |