Catheter related Blood stream infection
🧾 About
- 🧪 The decision to urgently remove an intravascular catheter depends on clinical judgment, balancing severity of sepsis and the likelihood of catheter-related infection (Mermel et al., 2001).
- 📊 Use the Visual Infusion Phlebitis (VIP) score to guide treatment decisions. A high score warrants prompt action.
🩺 Clinical Assessment
- Check for systemic infection: fever, chills, rigors ❄️🤒.
- Inspect catheter site for:
- 🔴 Redness, swelling, tenderness
- 💧 Discharge or pus → local infection
- 🩸 Thrombus formation or vein inflammation
- Look for severe sepsis/septic shock features:
- ⬇️ Hypotension
- ❤️ Tachycardia
- 🧠 Altered mental status, oliguria, organ dysfunction
🔎 Investigations
- Blood Cultures:
- Take 2 sets — 1 from the catheter, 1 from peripheral vein
- Compare growth times & colony counts → confirms CRBSI
- Catheter Tip Culture: Send if catheter is removed.
- Full Blood Count (FBC): 📈 Leukocytosis / neutrophilia.
- Inflammatory Markers: CRP, procalcitonin for severity.
- Imaging: 🖼️ Ultrasound or CT if abscess/thrombophlebitis suspected.
💊 Management
- Suspected Infection:
- Take swab of site + blood cultures before antibiotics 🧫.
- Empirical Antibiotics:
- ✅ First-Line: Flucloxacillin 500 mg PO QDS
- ⚠️ Penicillin allergy: Discuss alternatives with Microbiology
- 🧬 MRSA suspected: Vancomycin 1 g IV 12-hourly (adjust for renal function)
- Severe Sepsis / Septic Shock 🚨:
- Immediate Microbiology consult
- Broad-spectrum IV antibiotics
- Supportive measures: fluids, oxygen, vasopressors 💉
💡 Key Point:
Always reassess: if infection control is not achieved with antibiotics, catheter removal is often essential.