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| ๐งฌ Process | โ๏ธ Rate-Limiting Enzyme | ๐ Regulators |
|---|---|---|
| Glycolysis | Phosphofructokinase-1 (PFK-1) | AMP โ, Fructose-2,6-bisphosphate โ
ATP โ, Citrate โ |
| Gluconeogenesis | Fructose-1,6-bisphosphatase | AMP โ, Fructose-2,6-bisphosphate โ |
| TCA Cycle | Isocitrate Dehydrogenase | ADP โ
ATP โ, NADH โ |
| Glycogenesis | Glycogen Synthase | Glucose-6-P โ, Insulin โ, Cortisol โ
Epinephrine โ, Glucagon โ |
| Glycogenolysis | Glycogen Phosphorylase | Epinephrine โ, Glucagon โ, AMP โ
Glucose-6-P โ, Insulin โ, ATP โ |
| HMP Shunt | Glucose-6-Phosphate Dehydrogenase (G6PD) | NADP+ โ
NADPH โ |
| De Novo Pyrimidine Synthesis | Carbamoyl Phosphate Synthetase II | ATP โ, PRPP โ
UTP โ |
| De Novo Purine Synthesis | PRPP Amidotransferase | AMP โ, IMP โ, GMP โ |
| Urea Cycle | Carbamoyl Phosphate Synthetase I | N-Acetylglutamate โ |
| Fatty Acid Synthesis | Acetyl-CoA Carboxylase (ACC) | Insulin โ, Citrate โ
Glucagon โ, Palmitoyl-CoA โ |
| Fatty Acid Oxidation | Carnitine Acyltransferase I | Malonyl-CoA โ |
| Ketogenesis | HMG-CoA Synthase | โ |
| Cholesterol Synthesis | HMG-CoA Reductase | Insulin โ, Thyroxine โ, Estrogen โ
Glucagon โ, Cholesterol โ |