Makindo Medical Notes"One small step for man, one large step for Makindo" |
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MEDICAL DISCLAIMER: The contents are under continuing development and improvements and despite all efforts may contain errors of omission or fact. This is not to be used for the assessment, diagnosis, or management of patients. It should not be regarded as medical advice by healthcare workers or laypeople. It is for educational purposes only. Please adhere to your local protocols. Use the BNF for drug information. If you are unwell please seek urgent healthcare advice. If you do not accept this then please do not use the website. Makindo Ltd. |
📚 Related Subjects: | Atrial Fibrillation | Sinus Tachycardia | Sinus Arrhythmia | Multifocal Atrial Tachycardia | Resuscitation - Adult Tachycardia Algorithm
⚠️ Clinical Pearls: - 🚬 Smokers often need higher doses due to increased clearance. - 👴 Elderly or those with CCF require smaller doses. - 📌 Always prescribe by brand – formulations differ in bioavailability. - 🔄 Multiple interactions: always cross-check with other medications.
Always check the BNF link here.
Preparation | Details |
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Aminophylline Oral (non-smokers) | 225–450 mg BD (PO) |
Aminophylline Oral (smokers) | 350–700 mg BD (PO) |
IV Loading dose (if not already on drug) | 5 mg/kg (~250–500 mg) once, IV over 1 hour |
IV Maintenance infusion |
500–750 mg / 24 hrs (IV continuous)
🎯 Target plasma level: 10–20 mg/L 💉 Take level 4–6 hrs after starting infusion. ⏳ If stopping infusion → wait 15 min before sampling. |