• @About this App Makindo
  • @Contributers
  • @Developer and Author
  • @Join Team Makindo
  • @Makindo Questions
  • @Privacy and Data Policy
  • ACTH (Adrenocorticotropic hormone)
  • AF and Anticoagulation ✅
  • AFP (Alpha-fetoprotein) Testing
  • AIDS (HIV) Neurological Disease
  • AIDS (HIV) Respiratory disease
  • AIDS Dementia Complex (HIV) ✅
  • AIDS HAART Antiretroviral Drugs ✅
  • AIDS HIV Infection and a Fever ✅
  • AIDS(HIV) Gastrointestinal Disease ✅
  • APGAR Scoring (Children)
  • APTT and Coagulation
  • Abacavir 💊
  • Abatacept 💊
  • Abbey Pain Scale
  • Abbreviated Mental Test Score (AMTS)
  • Abciximab 💊
  • Abdominal Aortic Aneurysm (AAA) ✅
  • Abdominal Distension
  • Abdominal Mass (Child health)
  • Abdominal Masses: Clinical Approach and Considerations
  • Abdominal X Ray Collections
  • Abdominal X-Ray (AXR)
  • Abdominal paracentesis for ascites
  • Abducent Nerve (Cranial Nerve VI)
  • Abetalipoproteinemia (Bassen-Kornzweig Syndrome)
  • Abnormal Involuntary Movements
  • Abnormal eating exercising behaviour (Children)
  • Abnormal urinalysis
  • Abscess - General
  • Absence Seizure
  • Acamprosate 💊
  • Acanthocytes
  • Acanthosis Nigricans
  • Acarbose 💊
  • Accelerated Idioventricular Rhythm ❤️
  • Accessory Nerve (Cranial Nerve XI)
  • Acetazolamide 💊
  • Acetylcholine Receptor Antibodies
  • Acetylcholinesterase inhibitors
  • Achalasia
  • Achenbach’s syndrome
  • Achilles Tendon rupture
  • Achondroplasia ✅
  • Aciclovir 💊
  • Acid maltase deficiency (Pompe disease)
  • Acid-Base abnorrmalities
  • Acne Vulgaris ✅
  • Acoustic Neuroma ✅
  • Acquired Long QT syndrome (LQTS)
  • Acrodermatitis enteropathica (Children)
  • Acromegaly and Giantism ✅
  • Acromio-clavicular joint
  • Actinic Keratosis
  • Actinomyces israeli
  • Action Potential Neuron Versus Cardiac Ventricular Myocyte
  • Activated Charcoal
  • Active Proctitis ✅
  • Actrapid (Insulin) 💊
  • Acute (Ascending) Cholangitis ✅
  • Acute Abdomen - Perforation of a Viscus
  • Acute Abdominal Pain (OSCE focused)
  • Acute Abdominal Pain - Children ✅
  • Acute Abdominal Pain in Adults
  • Acute Acalculous Cholecystitis✅
  • Acute Airway Obstruction
  • Acute Anaphylactoid Reactions
  • Acute Anaphylaxis ✅
  • Acute Appendicitis (OSCE focused)
  • Acute Appendicitis in Children ✅
  • Acute Appendicitis ✅
  • Acute Bacterial Meningitis (Adults) ✅
  • Acute Bacterial Meningitis in Children ✅
  • Acute Bacterial Prostatitis ✅
  • Acute Blepharitis
  • Acute Bronchitis ✅
  • Acute Cardiogenic Pulmonary Oedema (CPO/LVF) ❤️
  • Acute Change in Vision or Vision Loss (OSCE focused)
  • Acute Chest Syndrome (Sickle Cell) ✅
  • Acute Cholecystitis ✅
  • Acute Colonic Pseudo-obstruction
  • Acute Compartment Syndrome
  • Acute Coronary Syndrome (ACS) NSTEMI USA ❤️
  • Acute Coronary Syndrome (ACS) STEMI ❤️
  • Acute Coronary Syndrome (ACS): Chest Pain ❤️
  • Acute Coronary Syndrome (ACS): Complications
  • Acute Coronary Syndrome Grace score ❤️
  • Acute Coronary Syndrome TIMI Score
  • Acute Coronary Syndrome: Cardiac Thrombolysis ❤️
  • Acute Coronary Syndrome: LBBB and AMI
  • Acute Coronary Syndrome: Overview
  • Acute Coronary Syndrome: Unstable Angina
  • Acute Coronary: Percutaneous Coronary Intervention
  • Acute Delirium
  • Acute Disc Prolapse
  • Acute Disseminated Encephalomyelitis
  • Acute Dystonic Reaction
  • Acute Encephalitis
  • Acute Eosinophilic Pneumonia
  • Acute Epiglottitis
  • Acute Exacerbation of COPD✅
  • Acute Fatty Liver of Pregnancy
  • Acute Glaucoma
  • Acute Glomerulonephritis in Children ✅
  • Acute Hepatic Porphyrias ✅
  • Acute Hepatitis and Acute Liver disease
  • Acute Hydrocephalus
  • Acute Hypotension ✅
  • Acute Inflammation
  • Acute Intermittent Porphyria (AIP)
  • Acute Interstitial nephritis
  • Acute Joint Pain and Swelling (Children)
  • Acute Kidney Injury ✅
  • Acute Limb Ischaemia
  • Acute Liver Disease & Acute Liver Failure ✅
  • Acute Lymphangitis
  • Acute Lymphoblastic Leukaemia (ALL) ✅
  • Acute Monoarthritis
  • Acute Myeloblastic Leukaemia (AML) ✅
  • Acute Myocarditis ✅
  • Acute Neck Injury (no fracture)
  • Acute Necrotizing Ulcerative Gingivitis
  • Acute Pancreatitis ✅
  • Acute Pericarditis ✅
  • Acute Phase reactants
  • Acute Promyelocytic Leukaemia (APML)
  • Acute Psychosis / Agitation
  • Acute Pyelonephritis and Urosepsis (UTI) ✅
  • Acute Radiation Syndromes
  • Acute Renal / Ureteric Colic and Urinary Tract Stones ✅
  • Acute Respiratory Distress Syndrome (ARDS)✅
  • Acute Retroviral Syndrome (HIV)
  • Acute Rhabdomyolysis ✅
  • Acute Right-Sided Weakness (OSCE focused) 🧠
  • Acute Rotator Cuff Tear
  • Acute Severe Asthma (Status Asthmaticus)✅
  • Acute Severe Colitis
  • Acute Stroke Care Guidance UK Ireland 2023
  • Acute Tracheitis
  • Acute Urinary Retention
  • Acute Uterine Haemorrhage ✅
  • Acute and Chronic Diarrhoea ✅
  • Acute and Chronic Gout ✅
  • Acute on Chronic Liver Disease Decompensation
  • Acute rash (Child Health)
  • Acutely Ill Critical care patient with High NEWS
  • Acutely Ill Patient with Parkinson's disease
  • Adalimumab 💊
  • Addenbrooke's Cognitive Examination-Revised (ACER)
  • Addison Disease (Adrenal Insufficiency)
  • Adefovir 💊
  • Adenocarcinoma of the Ampulla of vater
  • Adenosine deaminase deficiency
  • Adenosine 💊
  • Adhesive Capsulitis (Frozen Shoulder) ✅
  • Administer IV Injection
  • Adrenal Adenomas
  • Adrenal Cancer
  • Adrenal Masses Incidentalomas
  • Adrenal crises (Paediatric) ✅
  • Adrenaline (Epinephrine) 💊
  • Adrenoleukodystrophy
  • Adrenomyeloneuropathy
  • Adult Hypertension ✅
  • Adult Onset Stills Disease
  • Adult Polycystic kidney disease ✅
  • Adverse Drug Effects
  • African Trypanosomiasis (Sleeping sickness)
  • Age-Related Macular Degeneration (ARMD)
  • Aicardi syndrome
  • Air Embolism ✅
  • Alberta Stroke program Early CT score (ASPECT) scoring system
  • Albumin
  • Albumin-Protein Creatinine Ratio (PCR)
  • Alcohol Metabolism
  • Alcohol Withdrawal (Delirium Tremens)
  • Alcoholic Hepatitis
  • Alcoholic Ketoacidosis
  • Aldosterone
  • Alendronate (Alendronic acid) 💊
  • Alfacalcidol 💊
  • Algorithms
  • Alkaline phosphatase (ALP)
  • Alkalinisation of urine
  • Alkaptonuria
  • Allergic Bronchopulmonary Aspergillosis
  • Allergic Rhinitis
  • Allergic disorders
  • Allergies
  • Allogeneic stem cell transplantation
  • Allopurinol 💊
  • Alogliptin (Vipidia) 💊
  • Alopecia Areata
  • Alopecia ✅
  • Alpha Thalassaemia ✅
  • Alpha subunit (ASU) of TSH
  • Alpha-1 Antitrypsin (AAT) deficiency
  • Alport's Syndrome
  • Alteplase 💊
  • Altitude sickness / Acute Mountain sickness
  • Aluminium and Magnesium Antacids
  • Alveolar Gas Equation
  • Alzheimer disease (Dementia) ✅
  • Amantadine 💊
  • Amaurosis fugax
  • Amblyopia
  • Ameloblastoma
  • Amenorrhoea
  • American Trypanosomiasis (Chagas Disease)
  • Amiloride
  • Amino acids
  • Aminoglycosides 💊
  • Aminophylline 💊
  • Aminosalicylates 💊
  • Amiodarone and Thyroid disease
  • Amiodarone 💊
  • Amitriptyline 💊
  • Amlodipine 💊
  • Ammonia Encephalopathy
  • Amnestic syndromes and Memory Disorders
  • Amoebiasis Amoebic (Entamoeba histolytica)
  • Amoxicillin 💊
  • Amphetamine toxicity⚠️
  • Amphotericin B 💊
  • Ampicillin 💊
  • Amputations
  • Anaemia (Child Health)
  • Anaemia (Pregnancy)
  • Anaemia in Chronic Kidney Disease
  • Anaemia of Chronic Disease ✅
  • Anaemia: Assessment ✅
  • Anagrelide 💊
  • Anakinra 💊
  • Anal Cancer ✅
  • Anal Fissure
  • Analgesic Nephropathy
  • Anaromy and Physiology of the Brain
  • Anatomy and Phsyiology of the Ear
  • Anatomy and Physiology of the Pituitary
  • Anatomy and Physiology of Cilia
  • Anatomy and Physiology of Female Genitalia and Reproduction
  • Anatomy and Physiology of Male Genitalia
  • Anatomy and Physiology of Nerves
  • Anatomy and Physiology of Ribs and Chest Wall
  • Anatomy and Physiology of Small Bowel
  • Anatomy and Physiology of the Abdomen
  • Anatomy and Physiology of the Adrenal Gland
  • Anatomy and Physiology of the Basal Ganglia
  • Anatomy and Physiology of the Biliary system
  • Anatomy and Physiology of the Bladder
  • Anatomy and Physiology of the Bone Marrow
  • Anatomy and Physiology of the Brainstem
  • Anatomy and Physiology of the Breast
  • Anatomy and Physiology of the Cauda equina
  • Anatomy and Physiology of the Cerebellum
  • Anatomy and Physiology of the Cerebral Cortex
  • Anatomy and Physiology of the Coronary Arteries
  • Anatomy and Physiology of the Diaphragm
  • Anatomy and Physiology of the Eye
  • Anatomy and Physiology of the Glomerulus
  • Anatomy and Physiology of the Heart
  • Anatomy and Physiology of the Kidneys
  • Anatomy and Physiology of the Large Bowel (Colon, Rectum, Anal Canal)
  • Anatomy and Physiology of the Larynx
  • Anatomy and Physiology of the Liver
  • Anatomy and Physiology of the Lungs
  • Anatomy and Physiology of the Nose
  • Anatomy and Physiology of the Oesophagus
  • Anatomy and Physiology of the Ovary
  • Anatomy and Physiology of the Pancreas
  • Anatomy and Physiology of the Parathyroid Gland
  • Anatomy and Physiology of the Pelvis
  • Anatomy and Physiology of the Pharynx
  • Anatomy and Physiology of the Rectum
  • Anatomy and Physiology of the Spinal Cord
  • Anatomy and Physiology of the Spine
  • Anatomy and Physiology of the Spleen
  • Anatomy and Physiology of the Stomach
  • Anatomy and Physiology of the Thorax
  • Anatomy and Physiology of the Thymus Gland
  • Anatomy and Physiology of the Thyroid Gland
  • Anatomy and Physiology of the Uterus and Fallopian Tubes
  • Anatomy and Physiology of the Vascular System
  • Anatomy and Physiology of the vagina
  • Anatomy and Physiology: Human
  • Anatomy of Cells and Physiology
  • Anatomy of Dentistry
  • Anatomy of the Hand
  • Anatomy of the Inguinal and Femoral canal
  • Anatomy of the Muscles
  • Anatomy of the Skin
  • Anatony and Physiology of the Nephron
  • Andexanet alfa
  • Androgen insensitivity syndrome
  • Aneurysms, ischaemic limb and occlusions
  • Angina bullosa haemorrhagica
  • Angiodysplasia
  • Angiomyolipoma
  • Angioneurotic Oedema
  • Angiotensin Converting Enzyme Inhibitors
  • Angiotensin Converting enzyme (ACE) 💊
  • Angular Stomatitis - Cheilitis
  • Anion Gap and Metabolic Acidosis
  • Ankle-Brachial Pressure Index (OSCE focused)
  • Ankylosing spondylitis
  • Anogenital Warts (HPV) ✅
  • Anomalous Coronary Arteries
  • Anorexia Nervosa
  • Anosmia
  • Antacid medication
  • Anterior / Medial Medullary Infarct (Dejerine Syndrome)
  • Anterior Choroidal Artery Ischaemic Stroke
  • Anterior Cruciate ligament injury
  • Anterior Horn Cell diseases
  • Anterior Spinal Cord syndrome
  • Anterior circulation Brain
  • Anthrax (Bacillus anthracis)
  • Anti microbial stewardship ✅
  • Anti-Citrullinated Protein Antibody (ACPA)
  • Anti-D immunoglobulin
  • Anti-Hu antibodies
  • Anti-NMDA (NMDAR) receptor encephalitis
  • Anti-OKT3 antibodies
  • Anti-RNP Antibody
  • Anti-Yo antibodies
  • Anti-neutrophilic cytoplasmic antibodies (ANCA)
  • Antiarrhythmic agents
  • Antibiotic Guidelines✅
  • Antibiotics Mechanisms
  • Antibiotics for Abdominal Infections
  • Anticholinergic Burden
  • Anticholinergic syndrome
  • Anticipation
  • Anticoagulation and Antithrombotic
  • Antidiuretic hormone (Vasopressin)
  • Antigen presenting cells
  • Antimicrobial Choices
  • Antimicrobial agents
  • Antimuscarinic drugs 💊
  • Antiphospholipid Syndrome
  • Antithrombin III deficiency (AT3)
  • Anuria and Oliguria
  • Anxiety Phobias and OCD
  • Anxiety disorder: generalised (GAD)
  • Aortic Dissection ✅
  • Aortic Regurgitation ✅
  • Aortic Sclerosis
  • Aortic Stenosis ✅
  • Aortoenteric fistula
  • Apathetic thyrotoxicosis
  • Apixaban 💊
  • Aplastic anaemia ✅
  • Apomorphine 💊
  • Apoptosis
  • Appendix Cancer Tumours
  • Approach to the Child with Respiratory Distress
  • Apraxia
  • Arachnoid cyst
  • Arnold Chiari malformation
  • Arrhythmias
  • Arrhythmogenic Right Ventricular Cardiomyopathy
  • Artemisinins 💊
  • Arterial blood gas sampling
  • Arterial thrombosis
  • Arteriovenous Malformations
  • Artery of Percheron stroke
  • Artery-to-artery embolic stroke
  • Artesunate
  • Arthritis Diagnosis Compared
  • Arthrocentesis and Synovial fluid analysis
  • Asbestos Related Lung disease
  • Ascites ✅
  • Aspergilloma
  • Aspergillus fumigatus
  • Aspirin 💊
  • Aspirin/Salicylate Toxicity
  • Assessing Hearing Loss
  • Assessing Significance
  • Assessing a Patient who is Shocked
  • Assessing and Painful Red eye
  • Assessment of Causes of Nausea 🤢
  • Assessment of causes of Vaginal Discharge
  • Asteatotic eczema
  • Asthma COPD overlap syndrome
  • Asthma✅
  • Astigmatism
  • Astrocytomas
  • Ataxia Telangiectasia
  • Atazanavir 💊
  • Atenolol 💊
  • Atherosclerosis ❤️
  • Atorvastatin 💊
  • Atracurium
  • Atrial Ectopic beats
  • Atrial Fibrillation and Rhythm Control ✅
  • Atrial Natriuretic Peptide (ANP)
  • Atrial myxoma ❤️
  • Atrial septal defect (ASD) ✅
  • Atrioventricular Block
  • Atrioventricular Nodal Reentrant Tachycardia AVNRT ❤️
  • Atrophic vaginitis
  • Atropine Sulfate 💊
  • Attention deficit hyperactivity disorder
  • Auditory hallucinations
  • Autism spectrum disorder
  • Autoimmune Haemolytic anaemia (AIHA) ✅
  • Autoimmune Hepatitis ✅
  • Autoimmune Liver Disease Table ✅
  • Autoimmune Polyendocrine Syndromes
  • Automatic Implantable Cardioverter Defibrillator (AICD)
  • Autonomic Nervous System
  • Autonomic neuropathy ✅
  • Autosomal Dominant
  • Autosomal Recessive
  • Avascular Necrosis of Femoral head
  • Axillary Nerve
  • Azathioprine 💊
  • Azithromycin 💊
  • B lymphocytes
  • BRASH syndrome
  • BRCA genes (Familial Breast Cancer)
  • Bacillary Dysentery
  • Bacillus cereus poisoning
  • Back pain ✅
  • Backpain / Backache
  • Baclofen 💊
  • Bacteria and their Infections
  • Bacterial Vaginosis
  • Bacteroides fragilis
  • Baker's (Popliteal) Cyst
  • Balanitis (Adults)
  • Balanitis (Children)
  • Balkan endemic nephropathy (BEN)
  • Balsalazide (Aminosalicylate) 💊
  • Barrett's oesophagus ✅
  • Barthel Index
  • Bartonella
  • Bartonella henselae (Cat Scratch Disease)
  • Bartters syndrome
  • Basal Cell Carcinoma (BCC) ✅
  • Basic Chemistry for Medicine
  • Basic Concepts of Pregnancy
  • Basic Neuroscience
  • Basic Neuroscience
  • Basic Physics for Medicine
  • Basic Statistics
  • Basics of Endocrinology
  • Basilar artery thrombosis
  • Bayes' Theorem
  • Becker Muscular dystrophy
  • Beclometasone (Beclomethasone) 💊
  • Beer Potomania
  • Behaviour/personality change ✅
  • Behavioural and Psychological (BPSD) Symptoms of Dementia
  • Behavioural difficulties in Adults ✅
  • Behavioural difficulties in childhood
  • Behcet's Syndrome
  • Bejel ( Treponema pallidum subspecies endemicum)
  • Belantamab mafodotin (Blenrep)
  • Bell's Palsy (Facial nerve palsy)
  • Bendroflumethiazide (Bendrofluazide) 💊
  • Benign Breast Disease
  • Benign Eyelid Conditions
  • Benign Paroxysmal Positional Vertigo (BPPV)
  • Benign Prostatic Hyperplasia✅
  • Benign recurrent intrahepatic cholestasis
  • Benzodiazepine Toxicity
  • Benzodiazepines
  • Benzylpenicillin Sodium (Penicillin G) 💊
  • Berg Balance Scale
  • Beriplex 💊
  • Berylliosis
  • Beta Agonists 💊
  • Beta Antagonists/Blockers
  • Beta Blocker toxicity⚠️
  • Beta Thalassaemia ✅
  • Beta-2 Microglobulin
  • Beta-lactamases 💊
  • Betahistine (Serc) 💊
  • Bezafibrate 💊
  • Bezafibrate 💊
  • Biceps tendon rupture
  • Bilateral Pontine Infarction due to Basilar Artery Thrombosis
  • Bile salt malabsorption (BAM)
  • Biliary atresia
  • Bilirubin
  • Biochemical Lab values
  • Biochemistry and Physiology of Globins
  • Biological Agents
  • Bioterrorism
  • Birt-Hogg-Dubé Syndrome
  • Bisacodyl 💊
  • Bisoprolol 💊
  • Bisphosphonates 💊
  • Bites and stings
  • Blackouts and faints (TLOC)
  • Bladder Cancer
  • Bladder Stones
  • Blank Templates
  • Bleeding Antepartum
  • Bleeding Postpartum
  • Bleeding or High INR on Warfarin or other Anticoagulation
  • Bleomycin
  • Blindness - global causes
  • Blood
  • Blood Pressure
  • Blood Transfusion Reactions
  • Blood cultures
  • Blood film interpretation
  • Blood transfusion
  • Blotting Techniques: Gel Electrophoresis
  • Body Mass Index
  • Bone Pain
  • Bone Physiology
  • Bone disease Lab results
  • Bone metabolism RANK RANKL OPG pathway
  • Bone scintigraphy (Bone scan)
  • Bordetella pertussis (Whooping cough)
  • Borrelia burgdorferi
  • Borrelia recurrentis
  • Bortezomib
  • Botulism
  • Boxer's fracture
  • Brachial neuritis (neuralgic amyotrophy)
  • Brain Abscess
  • Brain CT Collection
  • Brain Embryology
  • Brain Herniation syndromes
  • Brain MRI
  • Brain MRI Collection
  • Brain Metastases
  • Brain Natriuretic Peptide (BNP)
  • Brain Tumours in Children
  • Brain Tumours ✅
  • Branchial cleft cyst
  • Breaking Bad News (OSCE)
  • Breast Cancer ✅
  • Breast Cysts
  • Breast Lump Evaluation
  • Breast abscess and Mastitis and Fat Necrosis
  • Breast tenderness/pain
  • Breathlessness
  • Bretylium 💊
  • Brighton Mobility Score
  • Broad Complex Tachycardia
  • Bromocriptine 💊
  • Bronchial adenoma
  • Bronchiectasis
  • Bronchiolitis
  • Bronchoscopy
  • Brown-Sequard Spinal Cord syndrome
  • Brucella
  • Brucellosis
  • Brugada syndrome ✅
  • Bruising
  • Budd-Chiari syndrome ✅
  • Budesonide 💊
  • Buerger disease (Thromboangiitis obliterans) ✅
  • Bulbar vs Pseudobulbar palsy
  • Bulimia Nervosa
  • Bullous Pemphigoid ✅
  • Bumetanide
  • Bunions
  • Buprenorphine 💊
  • Bupropion 💊
  • Burkholderia cepacia
  • Burkitt's lymphoma
  • Burns Management Guide
  • Busulphan (Busulfan)
  • Byssinosis
  • C Programming
  • C# programming
  • C++ Programming
  • CADASIL
  • CARASIL
  • CNS fungal Infections
  • CNS infections
  • CSF Interpretation
  • CSF Rhinorrhoea
  • CT Basics for Stroke
  • CT Pulmonary angiogram (CTPA)
  • Cabergoline
  • Caesarean Section (CS)
  • Café-au-lait spots
  • Caisson Disease Decompression sickness (The Bends)
  • Calcific Uraemic Arteriolopathy (Calciphyalxis)
  • Calcitonin
  • Calcitriol (1,25 Dihydroxycholecalciferol) 💊
  • Calcium Channel Blockers
  • Calcium Chloride or Gluconate
  • Calcium Physiology
  • Calcium Pyrophosphate Deposition (Pseudogout)
  • Calcium Resonium
  • Calcium channel blockers toxicity⚠️
  • Calot's triangle
  • Campylobacter jejuni
  • Canaliculitis
  • Cancer Pathology
  • Cancer and Stroke
  • Cancer of Unknown Primary
  • Candesartan 💊
  • Candida Skin Infections ✅
  • Candidiasis
  • Cannabinoid Hyperemesis Syndrome (CHS)
  • Cannabis toxicity⚠️
  • Cannonball Metastases
  • Capacity in Older Adult
  • Capecitabine 💊
  • Caplacizumab 💊
  • Capnocytophaga canimorsus
  • Capnography
  • Capreomycin
  • Capsular and Pontine Warning Syndromes
  • Captopri 💊
  • Carbamazepine 💊
  • Carbapenemase-producing Enterobacteriaceae
  • Carbimazole 💊
  • Carbohydrates
  • Carbon Monoxide Toxicity
  • Carbon Tetrachloride Toxicity
  • Carbon dioxide embolism
  • Carcinoembryonic antigen (CEA)
  • Carcinoid Heart Disease ❤️
  • Carcinoid Tumour Syndrome
  • Carcinoma of the Bile Duct
  • Carcinoma of the Gallbladder ✅
  • Cardiac Amyloid heart disease
  • Cardiac Arrest in Pregnancy
  • Cardiac Catheter ablation
  • Cardiac Crib Sheets
  • Cardiac Echocardiography: Basics and Uses
  • Cardiac Electrophysiology and Arrhythmia management
  • Cardiac Embryology
  • Cardiac MRI ❤️
  • Cardiac Resynchronisation Therapy (CRT) Pacemaker
  • Cardiac Syndrome X (Microvascular Angina)
  • Cardiac Troponins
  • Cardiac Troponins
  • Cardiac and Respiratory Rehabilitation
  • Cardioembolic stroke
  • Cardiogenic shock
  • Cardiological Emergencies: Revision ✅
  • Cardiology Examination (OSCE)
  • Cardiology Revision Guide ✅
  • Cardiopulmonary bypass
  • Cardiorespiratory Arrest
  • Caring for Patients with Dementia
  • Carmustine 💊
  • Caroticocavernous Fistula
  • Carotid Artery Dissection
  • Carotid Body Tumour
  • Carotid Endarterectomy ✅
  • Carotid Sinus Syncope
  • Carotid Web
  • Carotid sinus massage
  • Carpal tunnel syndrome
  • Carvedilol 💊
  • Caspases
  • Castleman's disease
  • Cataract
  • Catheter Related UTI
  • Catheter related Blood stream infection
  • Cauda Equina Syndrome (CES)
  • Caudate Nucleus
  • Causes of Eosinophila
  • Causes of Fatigue
  • Causes of Gradual Visual Loss over weeks and months
  • Causes of Ketoacidosis
  • Causes of Limp in Children
  • Causes of Neck Pain/Stiffness
  • Causes of Precious Puberty in Children
  • Causes of Ptosis
  • Causes of Short Stature in Children
  • Causes of Stroke
  • Causes of Tall Stature in Children
  • Causes of Tremor
  • Causes of Vertigo
  • Causes of a high Erythrocyte Sedimentation rate (ESR)
  • Causes of abnormal Vaginal bleeding
  • Causes of delayed Onset of Puberty in Children ✅
  • Causes of high C reactive protein (CRP)
  • Cavernous angiomas (Cavernomas)
  • Cavernous sinus
  • Cavernous sinus thrombosis
  • Cefaclor 💊
  • Cefalexin 💊
  • Cefotaxime 💊
  • Ceftazidime 💊
  • Ceftriaxone 💊
  • Cefuroxime 💊
  • Celecoxib 💊
  • Cell Adhesion Molecules
  • Cell Biology
  • Cell Cycle
  • Cell Response to Injury
  • Cellulitis and Erysipelas ✅
  • Central Pontine Myelinolysis (Osmotic Demyelination Syndrome) ✅
  • Central Retinal Arterial Occlusion (CRAO)
  • Central Spinal Cord Syndrome
  • Central Venous line Insertion
  • Central and Branch Retinal Vein Occlusion (CRVO/BRVO)
  • Centronuclear Myopathy (CNM)
  • Cerebellar Examination (OSCE)
  • Cerebellar Haemorrhage
  • Cerebellar Ischaemic Stroke
  • Cerebral Amyloid angiopathy (CAA) ✅
  • Cerebral Angiitis
  • Cerebral Angiography
  • Cerebral Angiography and Perfusion
  • Cerebral Arterial Perfusion and Clinical Correlates
  • Cerebral Atrophy vs Hydrocephalus
  • Cerebral Cortex
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  • Endocrine Emergencies: Revision ✅
  • Endocrinology Revision Guide ✅
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  • Erythema Multiforme ✅
  • Erythema Nodosum
  • Erythema ab Igne
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  • Euglycaemic Ketoacidosis (euDKA) with SGLT2 Inhibitors
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  • Exercise stress test
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  • Extrinsic Allergic alveolitis (Hypersensitivity Pneumonitis)
  • Eye Collection
  • Eye Trauma
  • Eye infections
  • Eye pain/discomfort
  • Ezetimibe 💊
  • FDG PET/CT Scans
  • Fabry disease
  • Facial Nerve (VII Cranial nerve)
  • Facial and Periorbital Swelling
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  • Facioscapulohumeral muscular dystrophy
  • Factor V Leiden Deficiency
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  • Faecal Incontinence
  • Failure to thrive or Faltering growth
  • Falls
  • Familial Adenomatous polyposis (FAP) ✅
  • Familial Hyperlipidaemias
  • Familial Mediterranean Fever (FMF) ✅
  • Familial hypocalciuric hypercalcaemia (FHH)
  • Familial/Hereditary Amyloidosis
  • Family Tree (Pedigree)
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  • Famotidine 💊
  • Famous Medical Triads
  • Fanconi Anaemia
  • Fanconi Syndrome
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  • Fasciculation
  • Fast Atrial Fibrillation and Rate Control
  • Fat Metabolism
  • Fat embolism ✅
  • Fatal Familial Insomnia (FFI)
  • Fatty acids
  • Febrile convulsion
  • Felodipine (Dihydropyridine)
  • Femoral Hernia
  • Femoral Shaft Fractures
  • Femoral Vein Cannulation
  • Femoral nerve
  • Fentanyl - Fentanil
  • Ferritin
  • Ferrous Fumarate - Gluconate - Sulphate 💊
  • Fertilisation and Formation of Zygote
  • Fetal Alcohol Syndrome
  • Fetal-type Posterior cerebral artery (FTP)
  • Fever - all ages
  • Fever Pyrexia of unknown origin (FUO PUO)
  • Fever in IV Drug User (PUO)
  • Fever in a traveller
  • Fibrinogen
  • Fibromuscular Dysplasia ✅
  • Fibromyalgia ✅
  • Fibrotic Lung Disease
  • Fidaxomicin 💊
  • Fifth Disease (Erythrovirus B19 infection)
  • Finasteride (5 alpha-reductase inhibitor) 💊
  • Fire Safety for NHS Professionals
  • First Seizure
  • First Seizure (OSCE focused)
  • Fissure in Ano
  • Fistulo in Ano
  • Fit Notes in General Practice (UK)
  • Fits/seizures and Epilepsy (Children)
  • Fitz-Hugh Curtis Syndrome
  • Fixed Abnormal Beliefs (Delusions)
  • Flashes and Floaters in the Visual Field
  • Flecainide Acetate 💊
  • Flexor sheath infection (flexor tenosynovitis)
  • Flow Cytometry
  • Flucloxacillin 💊
  • Fluconazole 💊
  • Flucytosine 💊
  • Fludrocortisone 💊
  • Fluid balance status and management
  • Flumazenil (Annexate - Romazicon) 💊
  • Fluoxetine 💊
  • Focal Cortical Dysplasia (FCD)
  • Focal Segmental Glomerulosclerosis (FSGS)
  • Foix-Alajouanine syndrome
  • Folate (Folic) acid (B9) 💊
  • Folate deficiency (B9) ✅
  • Folinic acid (Leucovorin) 💊
  • Follicular lymphoma
  • Folliculitis
  • Fomepizole 💊
  • Fondaparinux 💊
  • Food Intolerance in Children
  • Food borne disease
  • Foot Drop
  • Forearm Fractures
  • Foreign Body in Eye
  • Foscarnet Sodium 💊
  • Fosfomycin
  • Foslevodopa / Foscarbidopa
  • Fosphenytoin 💊
  • Foster Kennedy Syndrome
  • Fourniers gangrene
  • Fractured Clavicle
  • Fractured Neck of Femur/Femoral Neck
  • Fractured Pubic Ramus
  • Fractured Scapula
  • Fractured Shaft Femur
  • Fractured Tibia and Fibula
  • Fractures in Children
  • Fractures of the Upper humerus
  • Fragile X syndrome
  • Frailty an Overview
  • Fraser guidelines and Gillick Competence
  • Free Radicals
  • Fresh Frozen Plasma
  • Friedreichs Ataxia
  • Frontotemporal dementia
  • Full or Complete Blood Count (FBC CBC)
  • Functional organization of a eukaryotic gene
  • Fungi and their infections
  • Furosemide (Frusemide)
  • Fusidic acid 💊
  • Fusobacteria - Tropical ulcer
  • Fusobacterium
  • G protein-coupled receptors
  • GLP-1 Receptor Agonists
  • Gabapentin 💊
  • Galactorrhoea
  • Galactosaemia
  • Galantamine
  • Gallstone ileus
  • Gallstones and biliary colic
  • Gamete intra-fallopian tube transfer (GIFT)
  • Gametogenesis
  • Gamma Glutamyl Transferase (GGT)
  • Gamma hydroxy butyrate (GHB) toxicity⚠️
  • Ganciclovir - Valganciclovir 💊
  • Ganglion Cysts
  • Gardner's syndrome
  • Gardnerella vaginalis
  • Gas Gangrene (Clostridial Myonecrosis)
  • Gastric (MALT) Lymphoma
  • Gastric Cancer ✅
  • Gastric Outlet obstruction (pyloric stenosis) in Adults ✅
  • Gastrinoma
  • Gastro Intestinal Stromal Tumours (GIST)
  • Gastro-Oesophageal Reflux (GORD/GERD) ✅
  • Gastro-Oesophageal Reflux (Paediatrics GORD) ✅
  • Gastro-oesophageal reflux in Children ✅
  • Gastroenteritis in Adults ✅
  • Gastroenteritis in Children
  • Gastroenterology Examination
  • Gastroenterology Examination (OSCE)
  • Gastroenterology Revision Article ✅
  • Gastrointestinal Emergencies:Revision✅
  • Gastrostomy (PEG) tube managment
  • Gaucher's disease
  • Gene components
  • General Anaesthesia (GA) 💤
  • General Basic Fracture management ✅
  • Genetic Diseases
  • Genetic Linkage
  • Genetic Mutations
  • Genital Ulcers
  • Gentamicin 💊
  • Geriatric Medicine Emergencies: Revision ✅
  • Geriatric Medicine Syllabus (For Resident Doctors in Training)
  • Gerstmann-Straussler-Scheinker Syndrome (GSS)
  • Gestational Diabetes Mellitus ✅
  • Giardiasis
  • Gilbert's syndrome ✅
  • Gingival (Gum) hyperplasia or hypertrophy
  • Gitelman's syndrome
  • Glasgow Coma scale
  • Glatiramer acetate (Copaxone) 💊
  • Glibenclamide 💊
  • Gliclazide
  • Glimepiride
  • Glioblastoma ✅
  • Glipizide
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  • Glucagon 💊
  • Glucagonoma
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  • Glutamate
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  • Glyceryl Trinitrate (GTN) 💊
  • Glycogen storage diseases
  • Glycolysis Krebs Electron Transport Chain
  • Glycopyrronium Bromide
  • Goitre ✅
  • Gold Score: Hypoglycaemia Awareness in Type 1 Diabetes ✅
  • Golfer's Elbow (Medial Epicondylitis)
  • Golimumab (Simponi) 💊
  • Gonorrhoea
  • Goodpasture's syndrome (Anti GBM disease)
  • Goserelin (Zoladex) 💊
  • Government Benefits Available to People with Disabilities UK
  • Gradenigo's syndrome
  • Grades of Recommendation
  • Gradual change in or loss of vision
  • Gram Stain
  • Granuloma annulare
  • Granulomas
  • Granulomatosis with Polyangiitis GPA (Wegeners)✅
  • Graves Disease (Thyrotoxicosis) ✅
  • Griseofulvin 💊
  • Growth Hormone Deficiency ✅
  • Guillain Barre Syndrome
  • Gum hypertrophy
  • Gynaecological Examination (OSCE)
  • Gynaecological History Taking
  • Gynaecomastia ✅
  • HAM- D Hamilton Anxiety Rating Scale
  • HAM-A: Hamilton Anxiety Rating Scale
  • HAS-BLED score
  • HIV and Post-Exposure Prophylaxis (PEP)
  • HIV and Pre-exposure prophylaxis
  • HIV associated nephropathy (HIVAN)
  • HIV disease New Diagnosis
  • HTLV-1 Associated myelopathy (Tropical Spastic Paraparesis)
  • Haematemesis
  • Haematology Emergencies: Revision ✅
  • Haematology Laboratory Values
  • Haematology Revision Guide ✅
  • Haematopoietic Stem Cell Transplantation (Previously Bone Marrow Transplantation)
  • Haematospermia
  • Haematuria
  • Haemoglobinopathies
  • Haemoglobins
  • Haemolytic Anaemia
  • Haemolytic Uraemic Syndrome (HUS) ✅
  • Haemolytic disease of the newborn
  • Haemophilia
  • Haemophilia A ✅
  • Haemophilia B ✅
  • Haemophilus aegyptius
  • Haemophilus ducreyi
  • Haemophilus influenzae
  • Haemophilus parainfluenzae
  • Haemopoiesis
  • Haemoptysis
  • Haemorrhagic Transformation of Infarction
  • Haemorrhagic stroke
  • Haemorrhoids (Piles) ✅
  • Hairy Cell Leukaemia
  • Hairy Leukoplakia
  • Hallervorden-Spatz disease (PKAN)
  • Haloperidol 💊
  • Hamman-Rich syndrome
  • Hand foot and mouth disease
  • Hand fractures and Injuries
  • Hantavirus infections
  • Haptoglobins
  • Harlequin ichthyosis
  • Hartmann's procedure
  • Hartmanns solution (Ringers lactate) 💊
  • Hartnup disease
  • Hashimoto's thyroiditis
  • Head Impulse Test
  • Head Injury and Traumatic Brain Head Injury (TBI)
  • Head Lice
  • Head and Neck Cancers
  • Headache - Basilar Migraine
  • Headache - Cluster
  • Headache - Medication Overuse Headache ✅
  • Headaches
  • Health Issues In Pregnancy
  • Health Safety and Manual Handling
  • Hearing Loss
  • Hearing aids
  • Heart Block
  • Heart Failure with preserved and reduced EF ✅
  • Heart Murmurs
  • Heart and Fetal circulation
  • Heat Stroke
  • Helicobacter pylori
  • Helvetica Spotted fever
  • Heme Synthesis, Biochemistry, and Physiology
  • Henoch-Schonlein purpura
  • Heparin - General 💊
  • Heparin - Low Molecular Weight Heparin 💊
  • Heparin - Unfractionated Heparin 💊
  • Heparin-induced thrombocytopenia (HIT) ✅
  • Hepatic Encephalopathy
  • Hepatitis (D) Delta Virus ✅
  • Hepatitis A ✅
  • Hepatitis B ✅
  • Hepatitis C
  • Hepatitis E ✅
  • Hepatocellular Carcinoma
  • Hepatology Emergencies: Revision
  • Hepatorenal syndromes
  • Hereditary Angio-Oedema
  • Hereditary Elliptocytosis 🩸
  • Hereditary Haemochromatosis
  • Hereditary Haemorrhagic Telangiectasia (HHT) ✅
  • Hereditary Spastic Paraparesis
  • Hereditary Spherocytosis (HS) 🩸
  • Hereditary neuropathy with pressure palsies
  • Hereditary non polyposis coli (Lynch syndrome) ✅
  • Hernias
  • Hernias (Children)
  • Herpes Simplex Encephalitis (HSV)
  • Herpes Simplex Virus
  • Herpes Varicella-Zoster (Shingles) Infection
  • Herpes Virus 6 and 7
  • Herpes Viruses
  • Herpes Zoster Ophthalmicus (HZO) Shingles
  • Herpes simplex keratitis (HSK)
  • Herpetic Whitlow
  • Heterochromia Iridium
  • Heyde syndrome
  • Hiatus hernia
  • Hiccups (Singultus)
  • Hidradenitis suppurativa (Acne Inversa)
  • Hierarchy of Evidence-Based Trials
  • High Altitude Physiology
  • High Dose Insulin Euglycaemic Therapy (HIET)
  • High Output Stoma
  • High Yield Cardiology
  • High Yield Endocrinology
  • High Yield Exam Geriatric
  • High Yield Gastroenterology
  • High Yield Infectious Diseases
  • High Yield Neurology
  • High Yield Renal / Electrolytes
  • High Yield Respiratory
  • High Yield Rheumatology / Autoimmune
  • High-Yield Oncology & Haematology
  • Hip Osteoarthritis ✅
  • Hip Pain (OSCE focused)
  • Hip pain in children
  • Hirschsprung disease (congenital megacolon)
  • Hirsuitism
  • Histones
  • Histoplasmosis
  • Hoarseness and voice change
  • Hodgkin Lymphoma ✅
  • Hodgkin vs Non-Hodgkin Lymphoma:
  • Holt-Oram syndrome
  • Holter monitor (tape) 24-72 h
  • Homocystinuria
  • Hookworm
  • Horner's syndrome
  • Horseshoe Kidney
  • Hospital acquired Pneumonia HAP ✅
  • Hospital-acquired infections
  • How does a CPU work
  • How to Read and Analyze a Medical Paper
  • Human Herpesvirus 6A (HHV-6A)
  • Human Leukocyte Antigen and its Role in Disease Associations
  • Human Metabolism
  • Human albumin solution (HAS)
  • Human papilloma virus infection
  • Human prion diseases
  • Humeral Fractures ✅
  • Hunter's syndrome (MPS-2)
  • Huntingtons Disease/Chorea
  • Hurler's syndrome (MPS-1)
  • Hutchinson-Gilford Progeria Syndrome (HGPS)
  • Hydatid disease (Echinococcus)
  • Hydatidiform mole
  • Hydralazine 💊
  • Hydrocephalus and Stroke
  • Hydrocortisone 💊
  • Hydrogen Bonds
  • Hydrogen and other Bonds
  • Hydrops fetalis
  • Hydroxocobalamin - Cyanocobalamin (B12) 💊
  • Hydroxocobalamin 💊
  • Hydroxychloroquine 💊
  • Hydroxyurea (Hydroxycarbamide)
  • Hyoscine (Buscopan) 💊
  • Hyper IgM syndrome
  • Hyperacute Stroke Care Pathway
  • Hyperbaric Oxygen therapy
  • Hypercalcaemia of Malignancy
  • Hypercalcaemia ✅
  • Hypercholesterolaemia
  • Hyperemesis Gravidarum
  • Hyperglycaemic Hyperosmolar State (HHS) ✅
  • Hyperinsulinaemic-euglycemic therapy (HIET)
  • Hyperkalaemia ✅
  • Hyperkalaemic and Hypokalaemic Periodic Paralysis
  • Hyperlipidaemia
  • Hypermagnesaemia
  • Hypernatraemia
  • Hyperparathyroidism
  • Hyperphosphataemia (High phosphate)
  • Hyperprolactinaemia
  • Hypertension in Children ✅
  • Hypertension in Pregnancy ✅
  • Hyperthermia and Hypothermia
  • Hypertriglyceridaemia (HTG)
  • Hypertrophic cardiomyopathy (HCM - HOCM) ✅
  • Hyperuricaemia
  • Hyperventilation Syndrome
  • Hyperviscosity syndrome
  • Hyphaema (US Hyphema)
  • Hypocalcaemia ✅
  • Hypoglossal Nerve (Cranial Nerve XII)
  • Hypoglycaemia
  • Hypogonadism
  • Hypogonadism (Female)
  • Hypokalaemia
  • Hypokalaemic Periodic Paralysis
  • Hypomagnesaemia ✅
  • Hyponatraemia ✅
  • Hypophosphataemia (Low phosphate)
  • Hypopituitarism (Pituitary Failure)
  • Hypospadias
  • Hypothermia✅
  • Hypothyroidism ✅
  • Hypoxia - Reacting to Low Oxygen Saturations
  • Hypoxic-Ischaemic Encephalopathy
  • ICH Classification and Severity Scores
  • IL-12 receptor deficiency
  • IV Immunoglobulin (IVIG) 💊
  • Ibandronic acid (Bisphosphonate) 💊
  • Ibuprofen 💊
  • Icatibant 💊
  • Idarucizumab (Praxbind) 💊
  • Idiopathic Arthritis in Adults
  • Idiopathic Fascicular Left Ventricular Tachycardia
  • Idiopathic Intracranial hypertension ✅
  • Idiopathic Pulmonary Fibrosis
  • Idiopathic Ventricular Tachycardia (IVT)
  • IgA Nephropathy (Berger's disease)
  • Ileostomy vs Colostomy Table
  • Iliopsoas Abscess
  • Images - Spot diagnoses
  • Imaging for the MLA#1
  • Imaging for the MLA#2
  • Imatinib mesylate
  • Imipenem (Primaxin) with Cilastin 💊
  • Immediate management and assessment of the newborn
  • Immobility
  • Immune Reconstitution Syndrome
  • Immune Thrombocytopenic Purpura (ITP) 🩸
  • Immune response
  • Immune-Mediated Necrotizing Myopathy
  • Immunoglobulin G4-related disease (IgG4-RD)
  • Immunoglobulins and their role in Immunity
  • Impetigo
  • Important Metabolic Pathways
  • Impulse control disorders
  • In Situ Thrombosis 🩸
  • Incidental Findings (Incidentalomas)
  • Inclusion Body Myositis
  • Incubation periods
  • Indapamide 💊
  • Indications for Irradiated Blood Products
  • Indinavir (IND)
  • Infant feeding issues
  • Infantile Spasms (West Syndrome)
  • Infection Associated Cancers
  • Infection Prevention Control for NHS Staff
  • Infection Prevention Control for NHS Staff
  • Infection screening in Septic patient ✅
  • Infectious Colitis
  • Infectious Diarrhoea (OSCE focused)
  • Infectious Diseases Revision Guide ✅
  • Infectious Mononucleosis (EBV Most Often)
  • Infective Endocarditis
  • Infective Keratitis
  • Inferior Vena Cava Filter
  • Infertility & Subfertility
  • Inflammatory Bowel Disease
  • Inflammatory eye disease
  • Infliximab 💊
  • Influenza
  • Information Governance for NHS Staff
  • Inguinal Hernia
  • Inhaled Levodopa (Inbrija®)
  • Inherited Metabolic Diseases in Children
  • Initial Assessment of Malaria in Children
  • Injury Severity Score (ISS)
  • Insomnia - unable to sleep issues
  • Insulin Degludec (Tresiba)
  • Insulin Detemir (Levemir)
  • Insulin Glargine (Lantus, Abasaglar, Semglee, Toujeo)
  • Insulin Physiology
  • Insulin Pumps
  • Insulinoma
  • Interferon Beta 💊
  • Intermittent Claudication
  • Internal Capsule
  • Internal Jugular vein Cannulation
  • Internal; Decapitation
  • Internuclear Ophthalmoplegia
  • Interstitial Keratitis
  • Interstitial Lung Disease
  • Intestinal Ischaemia
  • Intestinal obstruction (Children)
  • Intestinal obstruction and Ileus
  • Intra Aortic Balloon Pump
  • Intraabdominal abscess
  • Intrauterine death ✅
  • Intravascular large B-cell lymphoma (IVLBCL)
  • Intravenous Iron Replacement
  • Intravenous fluids ✅
  • Intraventricular haemorrhage (neonates)
  • Introduction to Anaesthetics 💤
  • Introduction to Cardiology
  • Introduction to Hormones
  • Introduction to Obstetrics and Gynaecology
  • Introduction to Psychiatry
  • Intubation and Mechanical Ventilation
  • Intussusception in Adults
  • Intussusception in Children ✅
  • Investigations
  • Iodine Physiology
  • Iodine deficiency Goitre
  • Ipratropium Bromide (Atrovent) 💊
  • Irbesartan 💊
  • Iritis (Anterior Uveitis)
  • Iron Salts 💊
  • Iron Studies
  • Iron Studies
  • Iron deficiency Anaemia 🩸
  • Iron toxicity⚠️
  • Irritable bowel syndrome ✅
  • Ischaemic Colitis
  • Ischaemic Stroke
  • Ischaemic Strokes in the Pons
  • Ischaemic heart disease
  • Isoniazid 💊
  • Isoprenaline 💊
  • Isosorbide Dinitrate 💊
  • Isosorbide mononitrate 💊
  • Isotretinoin (Accutane) 💊
  • Ispaghula Husk (Fybogel) 💊
  • Ivabradine 💊
  • Jansen Disease
  • Janus kinase 2
  • Jaundice
  • Java Programming
  • Jervell and Lange-Nielsen syndrome
  • Job Syndrome (Hyper IgE syndrome)
  • Jugular Venous pressure
  • Junctional Tachycardia
  • Juvenile Dermatomyositis
  • Juvenile Idiopathic Arthritis (Stills Disease)
  • Juvenile Myoclonic epilepsy (JME)
  • Kallmanns syndrome
  • Kaposi sarcoma (KS)
  • Karnofsky performance status scale
  • Kawasaki disease
  • Keloids
  • Kennedy Syndrome (Spinal and Bulbar Muscular Atrophy (SBMA))
  • Keratoacanthoma
  • Keratoconus
  • Kernicterus
  • Ketamine bladder
  • Ketamine 💊
  • Ketoconazole 💊
  • Ketones
  • Klebsiella pneumonia
  • Kleine Levin Syndrome
  • Klinefelter Syndrome
  • Klumpke palsy
  • Knee Joint Structure and Form
  • Koebner phenomenon
  • Kugelberg-Welander Syndrome (Spinal Muscular Atrophy Type III)
  • Kuru
  • Kwashiorkor
  • L-Thyroxine (T4) 💊
  • Labetalol (Trandate) 💊
  • Labour and Complications
  • Labyrinthitis and Vestibular Neuronitis
  • Lac operon
  • Lacerations
  • Lacerations
  • Lactate
  • Lactate dehydrogenase (LDH)
  • Lactic acidosis
  • Lactobacillus acidophilus
  • Lactose Intolerance
  • Lactulose 💊
  • Lacunar Stroke Syndromes
  • Lady Windermere syndrome
  • Lambert-Eaton syndrome (LEMS)
  • Lamivudine (3TC) 💊
  • Lamotrigine 💊
  • Langerhans cell histiocytosis (LCH)
  • Language and Dysphasia
  • Lansoprazole 💊
  • Lanthanum
  • Large for Gestational Age (LGA)
  • Larva Currens (Strongyloides stercoralis)
  • Lassa haemorrhagic fever (LHF)
  • Lateral Medullary Syndrome
  • Law and Mental Health (UK)
  • Law and Mental Health (USA)
  • Laxatives 💊
  • Le Fort Fractures
  • Lead toxicity
  • Learning (Intellectual) disability
  • Leber hereditary optic neuropathy (LHON)
  • Lecanemab (Leqembi)
  • Leflunomide (Arava) 💊
  • Left Ventricular Outflow Tract (LVOT) Tachycardia
  • Legal definition of Blindness
  • Legionella Pneumophila
  • Leishmaniasis (Cutanenous and Visceral)
  • Lemierre's syndrome
  • Lenalidomide (Revlimid)
  • Length Dependent Polyneuropathy
  • Lennox-Gastaut syndrome
  • Lenticulostriate branch occlusion
  • Leprosy (Hansen’s disease)
  • Leptin
  • Leptomeningeal Metastases
  • Leptospira interrogans
  • Leptospirosis (Weil's Disease) (Notifiable)
  • Leriche syndrome (aortoiliac occlusive disease)
  • Lesch-Nyhan syndrome
  • Leukaemia
  • Leukoariosis
  • Leukocoria (White Pupillary Reflex) 👁️
  • Leukocyte alkaline phosphatase
  • Leukocytoclastic vasculitis
  • Leukotrienes
  • Levetiracetam (Keppra) 💊
  • Levobupivacaine
  • Levodopa 💊
  • Levomepromazine
  • Levosimendan 💊
  • Lhermitte Duclos Disease
  • Li Fraumeni syndrome
  • Lichen Planus ✅
  • Liddle's syndrome
  • Lidocaine(Lignocaine) 💊
  • Lightning strike
  • Limb Weakness
  • Limb girdle dystrophy
  • Limbic Encephalitis
  • Linagliptin (Trajenta) 💊
  • Linezolid
  • Liothyronine Sodium L-Triiodothyronine (T3) 💊
  • Lipid emulsion therapy - Intralipid 💊
  • Lipoatrophy
  • Lipoprotein lipase deficiency
  • Liraglutide (Victoza) 💊
  • Lisinopril 💊
  • Listerial Meningitis
  • Listeriosis
  • Lithium toxicity⚠️
  • Lithium 💊
  • Livedo Reticularis ✅
  • Liver Biopsy
  • Liver Examination (OSCE)
  • Liver Transplantation
  • Liver abscess ✅
  • Liver disease in Pregnancy
  • Local Anaesthetics for Suturing or other Procedures
  • Localisation of cortical function
  • Locked in Syndrome
  • Lofepramine 💊
  • Loffler's syndrome (Pulmonary Eosinophilia)
  • Loin Pain
  • Long COVID
  • Long QT syndrome (LQTS) Congenital
  • Long chain acyl-CoA dehydrogenase deficiency
  • Long term Oxygen therapy (LTOT)
  • Loop diuretics 💊
  • Loperamide 💊
  • Lopinavir 💊
  • Loratadine 💊
  • Lorazepam 💊
  • Losartan 💊
  • Loss of Libido
  • Loss of red reflex
  • Louse-Borne vs Tick-Borne Relapsing Fever
  • Louse-borne relapsing fever
  • Low CSF pressure Headache
  • Low mood/affective/depression problems
  • Lower Gastrointestinal Bleeding ✅
  • Lower Limb Fractures
  • Lower Limb Fractures and Injuries
  • Lower Limb Neurology (OSCE)
  • Lower Limb Soft Tissue Injuries
  • Lower respiratory tract infection (Child)
  • Lown Ganong Levine Syndrome (LGL) AVRT
  • Lugol iodine 💊
  • Lumbar and Sacrum anatomy and function
  • Lumbar puncture
  • Lumbrosacral Radiculopathy
  • Lump in Groin
  • Lung Abscess
  • Lung Cancer
  • Lung Empyema
  • Lung Transplant
  • Lupus Nephritis
  • Lupus Vulgaris
  • Lyme disease
  • Lymphadenopathy
  • Lymphocytes
  • Lymphocytic Hypophysitis
  • Lymphogranuloma Venereum (LGV)
  • Lymphoproliferative Disorders
  • Lyonization (X-Inactivation)
  • Lysergic acid diethylamide (LSD) Toxicity
  • Lysosomal storage diseases
  • MCAD Deficiency (Medium-Chain Acyl-CoA Dehydrogenase Deficiency)
  • MELAS
  • MR cholangiopancreatography (MRCP)
  • Macrocytic anaemia 🩸
  • Macroglossia
  • Macrophage activation syndrome (MAS)
  • Magnesium Physiology
  • Magnesium Sulphate - Sulfate
  • Magnetic resonance cholangiopancreatography
  • Magnetic resonance imaging
  • Major Disaster Plan
  • Major Histocompatibility complex
  • Malabsorption - small intestine ✅
  • Malaria
  • Malaria Falciparum (Includes Cerebral Malaria)
  • Male Urethral Catheterisation
  • Malignant Ascites
  • Malignant Breast Disease
  • Malignant Hyperparathyroidism due to PTHrP
  • Malignant Hyperpyrexia (Malignant Hyperthermia)
  • Malignant Hypertension
  • Malignant MCA syndrome ✅
  • Malignant Melanoma ✅
  • Malignant pleural mesothelioma
  • Mallet Finger
  • Mallory-Weiss Tear
  • Malnutrition Adults and the Elderly
  • Malnutrition Universal Screening Tool
  • Malnutrition universal screening tool (MUST)
  • Management of Bites
  • Mania
  • Mannitol
  • Mantle cell lymphoma
  • Maple Syrup Urine disease
  • Marantic Endocarditis
  • Marasmus
  • Maraviroc (Celsentri) 💊
  • Marburg virus disease
  • Marchiafava Bignami syndrome
  • Marfan syndrome
  • Marginal Keratitis
  • Marginal Zone Lymphoma
  • Mask-Related Acne (Maskne)
  • Massive Haemorrhage and Massive Transfusion Protocol (MTP)
  • Mastoiditis
  • Maths and Physics Crib Sheets
  • Maturity Onset Diabetes of the Young (MODY)
  • McArdles disease (type V)
  • McCune Albright syndrome
  • Measles (notifiable)
  • Mebeverine 💊
  • Mechanical Thrombectomy for Ischaemic Stroke
  • Meckel diverticulum ✅
  • Meconium
  • Median Nerve
  • Medical Licensing Assessment Content Map (GMC)
  • Medical Tweetorial Links
  • Medical conditions affecting the Teeth
  • Medullary Sponge kidney
  • Medulloblastoma
  • Mefenamic acid 💊
  • Mefloquine (Larium)
  • Megaloblastic anaemia 🩸
  • Melaena
  • Melatonin
  • Melioidosis (Burkholderia pseudomallei)
  • Memantine Hydrochloride 💊
  • Membranous Glomerulonephritis
  • Memory Loss
  • Menetrier disease
  • Menieres disease
  • Meningioma
  • Menkes Disease
  • Menopause and Menopausal Problems 🌸 ✅
  • Menstrual cycle
  • Menstrual problems
  • Mental Capacity Act 2005
  • Mental Health Act 1983
  • Mental capacity concerns
  • Mental health problems in pregnancy or postpartum 🤰
  • Mercaptopurine 💊
  • Meropenem 💊
  • Mesalazine (Aminosalicylate) 💊
  • Mesangiocapillary Glomerulonephritis
  • Mesenteric Ischaemia
  • Mesenteric adenitis
  • Mesial temporal lobe epilepsy
  • Metabolic Syndrome X ✅
  • Metabolic acidosis
  • Metabolic alkalosis
  • Metachromic leukodystrophy
  • Metastatic Adenocarcinoma
  • Metastatic Calcification
  • Metastatic bone disease
  • Metastatic disease
  • Metformin 💊
  • Methaemoglobinaemia
  • Methanol Toxicity
  • Methicillin Resistant Staphylococcus Aureus ✅
  • Methodone 💊
  • Methods to reduce toxin absorption
  • Methotrexate 💊
  • Methylcellulose 💊
  • Methylprednisolone
  • Methylthioninium chloride (Methylene blue)
  • Metoclopramide 💊
  • Metolazone 💊
  • Metoprolol 💊
  • Metronidazole (Flagyl) 💊
  • Metyrapone (Metopirone) 💊
  • Miconazole 💊
  • Microangiopathic Haemolytic anaemia
  • Microbiology and Assessment of Streptococcus
  • Microcytic anaemia 🩸
  • Microscopic Polyangiitis✅
  • Microscopic colitis
  • Microstomia
  • Microtubules
  • Midazolam
  • Middle East Resp Syndrome (MERS) Coronavirus
  • Midodrine 💊
  • Mifepristone
  • Migraine✅
  • Miliary (Disseminated) Tuberculosis
  • Miller-Fisher syndrome
  • Milrinone
  • Milwaukee shoulder syndrome
  • Mini Mental State Examination (MMSE)
  • Minimal Change Disease Glomerulonephritis
  • Minocycline 💊
  • Minoxidil 💊
  • Mirabegron 💊
  • Mirizzi syndrome
  • Mirtazapine 💊
  • Mirvetuximab soravtansine (Elahere)
  • Miscarriage
  • Misoprostol 💊
  • Misplaced Nasogastric tube insertion
  • Mitochondria
  • Mitochondrial diseases
  • Mitosis and Meiosis
  • Mitral Regurgitation (Incompetence)
  • Mitral Stenosis ✅
  • Mitral Stenosis vs Regurgitation
  • Mitral Valve prolapse ❤️
  • Mittelschmerz
  • Mixed Connective Tissue Disease (MCTD)
  • Mobility aids
  • Modified Oxford Handicap Scale (MOHS)
  • Modified Rankin Score
  • Modified Valsalva
  • Molecular Structures for Medicine
  • Molluscum contagiosum
  • MonkeyPox (MPOX)
  • Monoclonal gammopathy Undetermined significance
  • Monocytes 🩸
  • Monosodium glutamate (MSG) syndrome
  • Montelukast 💊
  • Montreal Cognitive Assessment (MOCA)
  • Moraxella catarrhalis
  • Morphine Sulphate 💊
  • Morphological Blood film abnormalities and variants
  • Mosquito borne diseases
  • Most Common Cancers in the UK & Red Flags
  • Motor End Plate
  • Motor Neuron Disease (MND-ALS)
  • Moyamoya disease
  • Muckle Wells syndrome
  • Multifocal Atrial Tachycardia
  • Multifocal Motor Neuropathy with Conduction block
  • Multiple Antithrombotics Anticoagulants
  • Multiple Crib sheets
  • Multiple Endocrine Neoplasia type 1 (MEN1)
  • Multiple Endocrine Neoplasia type II (MEN2)
  • Multiple Myeloma
  • Multiple Organ Dysfunction Syndrome
  • Multiple Pregnancy
  • Multiple Sclerosis (MS)
  • Multiple System Atrophy (MSA)
  • Mumps (Notifiable)
  • Muscle Pain Myalgia
  • Muscular Dystrophies
  • Musculocutaneous nerve
  • Musculoskeletal deformities
  • Musculoskeletal deformities
  • Myasthenia Gravis
  • Mycophenolate mofetil 💊
  • Mycoplasma pneumoniae 🫁
  • Mycoplasmas
  • Mycosis Fungoides (Sezary Syndrome)
  • Myelin Oligodendrocyte Glycoprotein (MOG) & MOG Antibody-Associated Disease (MOGAD)
  • Myelodysplastic syndrome (Myelodysplasia) 🩸
  • Myelofibrosis 🩸
  • Myelopathy (Disorder of Spinal cord)
  • Myeloproliferative disorders ✅
  • Myeloproliferative vs Lymphoproliferative Disorders
  • Myobacterium avium Complex Infection
  • Myocardial perfusion
  • Myoclonus
  • Myoglobin
  • Myotomes
  • Myotonic dystrophy - Dystrophia myotonica
  • Myxoedema coma
  • N-Acetylcysteine (Parvolex) 💊
  • NICE Guidance Part 1 ✅
  • NICE Guidance Part 2 ✅
  • NICE Guidance Part 3 ✅
  • NICE and other guidelines links
  • NICE and other guidelines links✅
  • NSAID toxicity⚠️
  • Nail disorders Table
  • Naloxone (Narcan) Opiate antagonist 💊
  • Naproxen
  • Narcolepsy
  • Narrow Complex Tachycardia ❤️
  • Nasal Discharge
  • Nasal Obstruction
  • Nasal polyps
  • Natalizumab (Tysabri) 💊
  • National Early Warning Score NEWS 2 Score
  • National Institutes of Health Stroke Scale (NIHSS)
  • Natural Language processing
  • Neck Swellings by Triangle
  • Necrotising Enterocolitis
  • Necrotising fasciitis
  • Needlestick injury and PEP
  • Nefopam 💊
  • Neisseria meningitidis (Meningococcus)
  • Nelson Syndrome
  • Nemaline myopathy
  • Neomycin 💊
  • Neonatal Abstinence Syndrome NAS
  • Neonatal Jaundice
  • Neonatal Lupus Erythematosus
  • Neonatal death or cot death
  • Neonatal death or cot death
  • Neonatal meningitis
  • Neostigmine 💊
  • Nephritic vs Nephrotic syndrome
  • Nephroblastoma (Wilm's tumour)
  • Nephrology Revision Guide ✅
  • Nephrotic Syndrome in Children ✅
  • Nephrotic syndrome in Adults
  • Nephrotoxic drugs
  • Nerve conduction studies
  • Neuroanatomy Images
  • Neuroblastoma
  • Neurocysticercosis (Taenia solium a pork parasite)
  • Neuroferrinopathy
  • Neurofibromatosis Type 1
  • Neurofibromatosis Type 2
  • Neuroleptic Malignant Syndrome
  • Neurological Examination - Cortical Functions
  • Neurological Examination - Motor
  • Neurological Examination - Speech&Language
  • Neurological Sensory Examination (OSCE)
  • Neurological examination - Eyes
  • Neurological or ENT Examination - Nystagmus
  • Neurological signs
  • Neurology Chapter
  • Neurology Crib Sheets
  • Neurology Revision Guide ✅
  • Neuromuscular weakness
  • Neuromyelitis Optica (Devic's disease)
  • Neuropathic Pain Management
  • Neuropathic pain
  • Neuroscience - Vision and Eye movements
  • Neuroscience of Memory
  • Neurosurgery
  • Neurotransmitters
  • Neutropenia
  • Neutropenic Sepsis
  • Neutrophil Alkaline Phosphatase
  • Neutrophils
  • Nevirapine (Viramune) NEV-NVP 💊
  • New Headache (OSCE focused)
  • New Onset Weakness (OSCE focused)
  • Newborn Bloodspot (Heel Prick) Screening
  • Niacin deficiency (Pellagra Vitamin B3)
  • Nicardipine (Cardene)
  • Nicorandil 💊
  • Niemann-Pick disease
  • Nifedipine 💊
  • Night sweats
  • Nikolsky's sign
  • Nimodipine (Nimotop) 💊
  • Nipple Discharge
  • Nirsevimab (Beyfortus)
  • Nitrates
  • Nitric Oxide
  • Nitrofurantoin 💊
  • Nitrous oxide use and abuse
  • Nizatidine 💊
  • Nocardia
  • Noise induced hearing loss
  • Non Alcoholic Fatty Liver Disease MASLD and MASH
  • Non Convulsive Status Epilepticus
  • Non Hodgkin Lymphoma ✅
  • Non gonococcal urethritis
  • Non invasive ventilation (NIV)
  • Non steroidal anti inflammatory drugs (NSAIDs) 💊
  • Non-Arteritic Anterior Ischaemic Optic Neuropathy
  • Non-accidental injury
  • Non-accidental injury (children)
  • Noonan syndrome
  • Noradrenaline (Norepinephrine) 💊
  • Normal Distribution
  • Normal Pressure Hydrocephalus
  • Normal Saline 0.9% ✅
  • Normal pregnancy and Antenatal care
  • Normocytic anaemia
  • Norovirus
  • Nortriptyline 💊
  • Norwegian Scabies ✅
  • Nosocomial infections
  • Notifiable disease and organisms UK
  • Nucleotides
  • Nutrition in Infants Breastfeeding
  • Nystatin 💊
  • OSCE Abdominal Examination
  • OSCE Ascites Examination
  • OSCE Blood pressure
  • OSCE Breast Anatomy Exam
  • OSCE Cardiac History Taking
  • OSCE Causes of Male Infertility
  • OSCE Cranial nerves and examination
  • OSCE Dysphagia Swallowing
  • OSCE Ear Examination
  • OSCE Examination of Visual Fields
  • OSCE Examining for Finger Clubbing
  • OSCE Examining the Arterial Pulse
  • OSCE Examining the Jugular Venous Pressure (JVP)
  • OSCE Eye Examination
  • OSCE Failure to Thrive
  • OSCE Gastroenterology History taking
  • OSCE Inguinal Examination
  • OSCE Jaundice
  • OSCE Leg Pain & Swelling
  • OSCE Lower Limb Neurological Examination
  • OSCE Male Genital exam
  • OSCE Monocular loss of vision
  • OSCE Neurological Examination - Cognition
  • OSCE Neurological Examination Face
  • OSCE Neurology - History taking
  • OSCE Rectal Bleeding
  • OSCE Respiratory - History Taking
  • OSCE Shoulder exam
  • OSCE Station Hearing Loss
  • OSCE Station – Melaena
  • OSCE Testicular/Scrotal Examination
  • OSCE Thyroid Exam
  • OSCE Unintentional Weight Loss
  • OSCE Upper Limb Neurology Examination
  • Obesity
  • Obesity and Pregnancy
  • Object orientated programming
  • Obsessive-Compulsive disorder
  • Obstetric definitions
  • Obstetrics Emergencies: Revision✅
  • Obstetrics and Gynaecology Revision Guide ✅
  • Obstructive Lung Diseases
  • Obstructive Shock (Mechanical Obstruction)
  • Obstructive Sleep Apnoea
  • Occupational Lung Disease
  • Octreotide 💊
  • Oculomotor Nerve (Cranial Nerve III)
  • Oesophageal Carcinoma
  • Oesophageal Perforation - Rupture
  • Oesophageal Variceal Bleeding
  • Oesophagogastroduodenoscopy (OGD/EGD)
  • Olanzapine 💊
  • Older Patient with Swallowing Problems
  • Olecranon Fracture
  • Olfactory Nerve (Cranial Nerve I)
  • Oligodendroglioma
  • Olmersartan 💊
  • Olsalazine (Aminosalicylate) 💊
  • Omalizumab
  • Omeprazole 💊
  • Onchocerciasis
  • Oncogenic viruses
  • Ondansetron 💊
  • Ophthalmic Emergencies: Revision ✅
  • Ophthalmic Nerve
  • Ophthalmology Exam Lists
  • Ophthalmology Revision Guide ✅
  • Opiates 💊
  • Opicapone 💊
  • Opioid/Opiate toxicity⚠️
  • Opsonisation
  • Optic Nerve (Cranial Nerve II) and tract
  • Optic Neuritis
  • Optic atrophy
  • Optics Pathway
  • Oral Aphthous Ulcers
  • Oral Candidiasis
  • Oral Leukoplakia
  • Orbital Cellulitis vs Preorbital Cellulitis
  • Orf (Contagious Ecthyma)
  • Organism and sensitivities
  • Organomegaly
  • Organophosphate (OP) Toxicity
  • Orphenadrine
  • Orthostatic Hypotension
  • Orthostatic Hypotension
  • Oseltamivir - Tamiflu 💊
  • Osteoarthritis
  • Osteochondroma
  • Osteogenesis Imperfecta
  • Osteogenic sarcoma (Osteosarcoma)
  • Osteomalacia
  • Osteomyelitis ✅
  • Osteonecrosis of the jaw
  • Osteopetrosis
  • Osteoporosis ✅
  • Otitis Externa (Malignant)
  • Otitis Media
  • Otosclerosis
  • Ottawa rules for ankle and foot x-ray
  • Ovarian Cancer
  • Ovarian Cyst
  • Ovarian Torsion
  • Overlap Syndrome
  • Oxford / Bamford Classification
  • Oxford Hip Score ✅
  • Oxford community stroke project (Bamford)
  • Oxidation and Reduction for Medical Students
  • Oxybutynin (Ditropan) 💊
  • Oxycodone (Oxycontin-Oxynorm) 💊
  • Oxygen delivery devices
  • Oxygenation and Ventilation
  • Oxytetracycline 💊
  • POEMS syndrome
  • Pabrinex 💊
  • Pacemakers
  • Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
  • Paediatric Crib Sheets
  • Paediatric emergencies
  • Paediatrics Revision Guide ✅
  • Pagets (Bone) disease
  • Pain Management : Acute & Chronic
  • Pain on inspiration
  • Painful Sexual Intercourse (Dyspareunia)
  • Painful Shoulder syndromes
  • Painful swollen leg
  • Palliation - Nausea Dyspnoea Secretions Pain
  • Palliation prescribing
  • Pallor
  • Palpitations
  • Pamidronate (Bisphosphonate) 💊
  • Panayiotopoulos Syndrome in Children
  • Pancoast tumour (Cancer)
  • Pancreatic Cancer
  • Pancytopenia
  • Panic Disorder
  • Panton-Valentine leucocidin toxin
  • Pantoprazole 💊
  • Pantothenate Kinase–Associated Neurodegeneration
  • Papilloedema
  • Paracetamol (Acetaminophen) toxicity⚠️
  • Paracetamol (Acetaminophen) 💊
  • Paracoccidioidomycosis
  • Paradoxical embolisation
  • Paraneoplastic Limbic Encephalitis (Dementia)
  • Paraneoplastic cerebellar degeneration
  • Paraphimosis (urological emergency)
  • Paraquat toxicity⚠️
  • Parkinson Hyperpyrexia Syndrome
  • Parkinson Plus syndromes
  • Parkinson disease
  • Parkinsonism
  • Paronychia
  • Parotitis
  • Paroxetine 💊
  • Paroxysmal Nocturnal Haemoglobinuria
  • Pasteurella multocida
  • Patau syndrome (trisomy 13)
  • Patellar Bursitis
  • Patent Ductus arteriosus (PDA) ❤️
  • Patent Foramen Ovale (PFO)
  • Pathological Gaits 🚶‍♂️
  • Pathological bone fracture
  • Patient on Anticoagulant and Antiplatelet Therapy
  • Patients who refuse treatment or lack capacity
  • Patiromer 💊
  • Pattern Recognition Receptors
  • Pectus Excavatum
  • Pegvisomant 💊
  • Pelvic Abscess
  • Pelvic Inflammatory Disease ✅
  • Pelvic Mass
  • Pelvic Pain
  • Pelvic fractures
  • Pemphigoid Gestationis (Herpes Gestationis) ✅
  • Pemphigus Vulgaris
  • Penetrating Abdominal Trauma ✅
  • Penicillamine 💊
  • Penicillin Allergy
  • Penicillins 💊
  • Penile Cancer
  • Peptic ulcer disease (PUD) and gastritis in Children
  • Peptic ulcer disease and Gastritis in Adults
  • Percutaneous Endoscopic Gastrostomy (PEG) procedure:
  • Pergolide
  • Perianal abscesses and fistulae ✅
  • Perianal symptoms
  • Pericardial Disease
  • Pericardial Effusion and Tamponade ✅
  • Perimesencephalic Subarachnoid haemorrhage ✅
  • Perindopril 💊
  • Perinephric abscess
  • Perioperative Anticoagulation
  • Perioperative Medicine ✅
  • Peripheral Arterial Disease (PAD) ✅
  • Peripheral Nerve Palsies
  • Peripheral nerve injuries/palsies (Children)
  • Peripheral neuropathy
  • Peripheral oedema and ankle swelling
  • Peripherally inserted central catheters (PICC)
  • Peritonitis
  • Peritonsillar Abscess (Quinsy) ✅
  • Pernicious anaemia
  • Personality Disorders
  • Perthes disease (Osteochondritis of the Hip)
  • Petechial Rash in Adult or Child
  • Pethidine
  • Peutz-Jeghers syndrome
  • Peyronie’s Disease
  • Phaeochromocytoma
  • Phagocytes
  • Pharmacokinetic
  • Pharmacokinetics
  • Pharmacology in the Elderly
  • Pharyngeal arch derivatives
  • Pharyngitis
  • Phenobarbital sodium
  • Phenoxymethylpenicillin (Penicillin V) 💊
  • Phentolamine 💊
  • Phenylketonuria (PKU)
  • Phenytoin (Dilantin) 💊
  • Philadelphia chromosome
  • Phimosis
  • Phobic disorders
  • Phocomelia and Thalidomide
  • Phosphorus/Phosphate
  • Phthiriasis palpebrarum ✅
  • Physical Education
  • Physics of flow for Medical students
  • Picolax - Citrafleet 💊
  • Pilonidal Abscess (sinus) ✅
  • Pinta (Treponema carateum)
  • Pioglitazone (Thiazolidinediones) 💊
  • Pituitary Apoplexy
  • Pituitary Tumours
  • Pityriasis or Tinea versicolor infections
  • Pityriasis rosea
  • Pivmecillinam (a penicillin antibiotic) 💊
  • Placenta praevia
  • Placental abruption
  • Plantar fasciitis
  • Plasmapheresis
  • Plasmids
  • Platelets
  • Pleural effusion
  • Pleural tap (thoracentesis)
  • Pneumococcal meningitis ✅
  • Pneumoconiosis ✅
  • Pneumocystis jirovecii pneumonia
  • Pneumonia in Children
  • Pneumonia 🩺 (OSCE focused)
  • Poisoning
  • Poisons eliminated Haemodialysis - perfusion
  • Poliomyelitis
  • Polyarteritis nodosa (PAN)
  • Polyarticular arthritis
  • Polycystic Ovary syndrome
  • Polycythaemia
  • Polycythaemia Vera (Primary Polycythaemia) ✅
  • Polydipsia (thirst)
  • Polymerase chain reaction
  • Polymorphic light eruption
  • Polymyalgia Rheumatica
  • Polymyositis
  • Polypharmacy and STOPP/START criteria
  • Polyuria
  • Polyuria and Thirst (OSCE focused)
  • Pontiac fever (Legionella Pneumophila)
  • Pontine-Midbrain haemorrhage ✅
  • Popliteal Artery Aneurysm
  • Porphyria Cutanea Tarda (PCT)
  • Porphyria Testing
  • Portal Hypertension
  • Positron and Single photon Emission Tomography
  • Post Falls Assessment
  • Post Menopausal Bleeding
  • Post Partum Thyroiditis
  • Post Polio Syndrome (PPS)
  • Post Streptococcal/Infectious Glomerulonephritis
  • Post Stroke Epilepsy (PSE)
  • Post-Traumatic Stress Disorder (PTSD)
  • Post-exposure prophylaxis with Immunoglobulins
  • Post-operative surgical care and complications
  • Post-transplant lymphoproliferative disorders (PTLDs)
  • Posterior Reversible Encephalopathy Syndrome (PRES)
  • Posterior circulation
  • Postmenopausal Bleeding (OSCE focused)
  • Postpartum / Postnatal Psychosis
  • Postpartum/Postnatal Depression
  • Postprandial hypotension
  • Postural Orthostatic Tachycardia Syndrome (POTS)
  • Post‑fall management: Concerns for the On‑Call Team
  • Potassium Physiology
  • Pralidoxime 💊
  • Pramipexole (Mirapexin) 💊
  • Prasugrel 💊
  • Pravastatin 💊
  • Praziquantel
  • Prazosin 💊
  • Pre-Operative Assessment
  • Pre-eclampsia, Gestational Hypertension
  • Prednisolone 💊
  • Prednisone 💊
  • Pregabalin 💊
  • Pregnancy risk assessment
  • Premature Menopause
  • Prematurity
  • Premed Anatomy
  • Premed Pathology 🔬
  • Premed Pharmacology
  • Premedical Biochemistry
  • Premedical Immunology 🧠
  • Premedical Microbiology 🧫
  • Presbyacusis(Presbycusis)
  • Prescribing in Pregnancy
  • Pressure sores or ulcers
  • Preterm labour
  • Prevotella (Bacteroides) melaninogenica
  • Priapism ✅
  • Primaquine
  • Primary Biliary Cholangitis
  • Primary CNS Lymphoma (PCNSL)
  • Primary Familial Brain Calcification (PFBC) Fahr Syndrome
  • Primary Open-Angle Glaucoma (POAG)
  • Primary Pulmonary Hypertension
  • Primary Sclerosing Cholangitis
  • Primary amoebic meningoencephalitis (PAM)
  • Primary and Secondary Hypoparathyroidism ✅
  • Primary ciliary dyskinesia and Kartagener's syndrome
  • Primary hyperaldosteronism (Conn's syndrome)
  • Primary progressive aphasia (Dementia)
  • Probenecid 💊
  • Procalcitonin (PCT) 🧪
  • Prochlorperazine (Stemetil) 💊
  • Procyclidine
  • Progressive Multifocal Leukoencephalopathy (PML)
  • Progressive Supranuclear Palsy (PSP)
  • Prolactin
  • Prolactinoma ✅
  • Propafenone 💊
  • Propantheline 💊
  • Propionibacterium
  • Propofol 💊
  • Propranolol 💊
  • Propylthiouracil 💊
  • Prostate cancer✅
  • Prosthetic Metal and Tissue Valves
  • Protamine Sulfate 💊
  • Protein C Deficiency ✅
  • Protein S Deficiency
  • Protein Synthesis
  • Protein losing enteropathy
  • Protein metabolism
  • Protein p53
  • Proteus
  • Prothrombin 20210A mutation
  • Prothrombin Complex Concentrates (Octaplex and Beriplex) 💊
  • Prothrombin time and Coagulation 🩸
  • Prothrombotic Hypercoagulable disorders
  • Proximal myopathy
  • Prucalopride
  • Pruritis
  • Pruritis ani
  • Psammoma bodies 🌀
  • Pseudo(pseudo)hypoparathyroidism
  • Pseudomonas infection (Pseudomonas aeruginosa)
  • Psoriasis
  • Psoriatic arthritis ✅
  • Psychogenic Polydipsia
  • Pubertal Development
  • Pubic Lice (Pediculosis Pubis)
  • Pulmonary Alveolar Proteinosis
  • Pulmonary Arteriovenous malformation
  • Pulmonary Arteriovenous malformation
  • Pulmonary Embolism 🫁
  • Pulmonary Eosinophilia and CXR changes
  • Pulmonary Haemorrhage
  • Pulmonary Hypertension
  • Pulmonary Regurgitation ❤️
  • Pulmonary Stenosis ❤️
  • Pulmonry Embolism in Pregnancy 🤰
  • Pulse oximetry
  • Pupils : Relative Afferent pupillary defect (RAPD)
  • Purpura
  • Purpura Fulminans
  • Putamen and Globus Pallidus
  • Putaminal Haemorrhage
  • Pyloric Stenosis Children
  • Pyoderma gangrenosum ✅
  • Pyonephrosis
  • Pyrazinamide 💊
  • Pyridostigmine 💊
  • Pyroglutamic acidosis
  • Pyruvate Kinase deficiency
  • Python Programming
  • QRISK3 (OSCE focused) ❤️
  • Quetiapine 💊
  • Quinine toxicity⚠️
  • Quinine 💊
  • RFS Rib fracture score
  • ROSIER scale
  • Rabies
  • Radial Head and Neck Fractures
  • Radial Ulnar and Median Palsy of the Hand
  • Radial nerve
  • Radiation exposure
  • Radicular syndromes
  • Radiculopathies
  • Radioactive iodine (I 131)
  • Radiofrequency Catheter Ablation
  • Radiologically Inserted Gastrostomy (RIG) Procedure
  • Radiology for finals
  • Raised intracranial pressure (ICP)
  • Raloxifene 💊
  • Raltegravir 💊
  • Ramipril 💊
  • Ramsay Hunt syndrome
  • Ranitidine 💊
  • Ranolazine 💊
  • Rapid Sequence Intubation (RSI)
  • Rapidly Progressive Glomerulonephritis (RPGN)
  • Rasagiline 💊
  • Rasburicase
  • Rate limiting steps in metabolism
  • Raynaud's Phenomenon Primary and Secondary
  • Reactive Arthritis
  • Rectal Foreign Body
  • Rectal Pain (Proctalgia)
  • Rectal Prolapse ✅
  • Rectal examination (OSCE)
  • Red Blood Cell Maturation
  • Red cell aplasia
  • Reduced/change in fetal movements
  • Refeeding syndrome
  • Referring to Level 2 or 3 care (ITU ICU HDU)
  • Reflex anoxic attacks in Children
  • Refractive Errors
  • Refsum disease
  • Regular Broad Complex Tachycardia ❤️
  • Rehabilitation in a Nutshell of older patients
  • Relapsing Polychondritis
  • Remdesvir (Veklury)
  • Renal Artery Stenosis Renovascular Disease
  • Renal Emergencies: Revision ✅
  • Renal Papillary Necrosis
  • Renal Replacement Therapy (RRT)
  • Renal Top Tips
  • Renal Transplantation
  • Renal Tubular Acidosis (RTA)
  • Renal Vein Thrombosis ✅
  • Renal cell carcinoma ✅
  • Renal syndromes
  • Renin and Aldosterone Renin ratio (ARR)
  • Renin-angiotensin system
  • Respiratory Examination (OSCE)
  • Respiratory Acidosis
  • Respiratory Alkalosis
  • Respiratory Arrest
  • Respiratory Arrest
  • Respiratory Crib Sheets
  • Respiratory Disease Investigations
  • Respiratory Distress Syndrome (Neonates)
  • Respiratory Emergencies: Revision✅
  • Respiratory Failure
  • Respiratory Revision Guide ✅
  • Respiratory Spirometry and Flow Volume Loops
  • Restless legs syndrome
  • Restriction enzymes
  • Restrictive Cardiomyopathy
  • Resus: Septic Shock and Sepsis
  • Resuscitation - Acute Haemorrhage
  • Resuscitation - Adult Bradycardia Algorithm
  • Resuscitation - Adult Tachycardia Algorithm
  • Resuscitation - Advanced Life Support
  • Resuscitation - Basic Life Support ABCDE
  • Resuscitation - Choking Algorithm
  • Resuscitation - Newborns and Children
  • Resuscitation - Post Resuscitation Algorithm
  • Reteplase 💊
  • Reticulocytes
  • Retinal detachment
  • Retinitis pigmentosa
  • Retinoblastoma 👁️
  • Retinoids 💊
  • Retinopathy of Prematurity (ROP)
  • Retroperitoneal fibrosis
  • Rett Syndrome
  • Reversible cerebral vasoconstriction syndrome (RCVS) ✅
  • Revision Core Syllabus Guide for Medical Students ✅
  • Reye syndrome
  • Rhesus haemolytic disease
  • Rheumatic fever ❤️
  • Rheumatoid Arthritis ✅
  • Rheumatology Autoantibodies
  • Rheumatology Drugs
  • Rheumatology Lab values
  • Rheumatology Revision Guide ✅
  • Rhino-Orbital-Cerebral Mucormycosis
  • Rhinosinusitis
  • Rhodococcus equi
  • Ribavirin 💊
  • Ribosomes
  • Ricin Toxicity
  • Rickettsia (General Principles)
  • Rickettsia africae (Tick Bite Fever)
  • Rickettsia akari (Rickettsial pox)
  • Rickettsia conorii (Mediterranean Spotted Fever)
  • Rickettsia prowazekii (Epidemi/Louse-borne Typhus)
  • Rickettsia rickettsii (Rocky Mountain spotted fever)
  • Rickettsia tsutsugamushi (Scrub typhus)
  • Rickettsia typhi (Murine/Endemic typhus)
  • Rifampicin (Rifabutin Rifampin) 💊
  • Rifaximin 💊
  • Right Iliac Fossa Pain
  • Right Ventricular Outflow Tract Tachycardia (RVOT)
  • Right Ventricular ST Elevation MI (RVMI)
  • Right heart valve disease
  • Rilipivirine (Edurant) RVP 💊
  • Riluzole (Rilutek)
  • Risedronate (Bisphosphonate) 💊
  • Risperidone 💊
  • Ritonavir (Norvir) RTV 💊
  • Rituximab (Mabthera) 💊
  • Rivaroxaban (Xarelto) 💊
  • Rivastigmine (Exelon) 💊
  • Rocky Mountain Spotted Fever
  • Rocuronium 💊
  • Role of Urinary Catheters in the Elderly
  • Rosacea ✅
  • Rotavirus
  • Rotigotine Transdermal Patch (Neupro) 💊
  • Rubella (German Measles) Notifiable
  • Ruptured Ovarian Cyst ✅
  • Rust Programming
  • SCL70 Antibody
  • SCOFF questionnaire screening tool
  • SQL programming
  • SUSS test for eating disorder examinations
  • Saccular Berry Cerebral Aneurysms
  • Sacubitril with Valsartan 💊
  • Safeguarding Adults and Children
  • Safety Surgical checklist WHO
  • Salivary Gland Disease
  • Salivary glands
  • Salmonella enterica
  • Salmonella typhi
  • Sampling in Medical Statistics
  • Saquinavir (Invirase) SQV 💊
  • Sarcoidosis
  • Saxagliptin (Onglyza) 💊
  • Scabies
  • Scaphoid fracture
  • Scarlet Fever (Scarlatina)
  • Scarring
  • Schamberg disease
  • Schistosomiasis
  • Schizophrenia
  • Schmidts syndrome
  • Sciatic nerve
  • Sciatica ✅
  • Scleritis
  • Scleroderma perforans of the sclera (scleromalacia perforans),
  • Scrotal/testicular pain/lump/swelling ⚠️
  • Seborrheic Dermatitis
  • Seborrheic Keratosis ✅
  • Secondary Hypertension
  • Secondary Messengers
  • Secondary Pulmonary hypertension - Cor pulmonale
  • Secondary dysmenorrhoea
  • Secondary hyperparathyroidism
  • Secondary prevention Post Acute Coronary Syndrome
  • Sedation and Analgesia on ITU
  • Selective IgA deficiency
  • Selective Serotonin reuptake Inhibitor toxicity⚠️
  • Selective serotonin reuptake inhibitors (SSRI) 💊
  • Selegiline 💊
  • Selenium deficiency
  • Self assessment form
  • Self-harm / Suicidal thoughts / Suicide ✅
  • Senior Self Assessment
  • Senna 💊
  • Septic Abortion ✅
  • Septic arthritis ✅
  • Seronegative Spondyloarthropathies
  • Serotonin syndrome
  • Serplulimab
  • Serratia
  • Sevelamer 💊
  • Severe combined immunodeficiency disorders
  • Shaft of Ulna Fracture
  • Sheehans syndrome
  • Shigella characteristics
  • Shigellosis (Bacillary Dysentery)
  • Shock in Pregnancy
  • Short QT Syndrome
  • Short Synacthen test (SST)
  • Shortness of Breath History (OSCE focused) 🫁
  • Shoulder Anterior Dislocations
  • Shoulder Joint Structure and Form
  • Shoulder: Posterior Dislocation
  • Sick Child/Neonate
  • Sick Euthyroid Syndrome ✅
  • Sick Sinus Syndrome (Tachy-Brady syndrome)
  • Sickle Cell Disease
  • Sideroblastic Anaemia
  • Sigmoid and Caecal Volvulus Adults
  • Sildenafil (Viagra) 💊
  • Silicosis
  • Simvastatin 💊
  • Sinus Bradycardia
  • Sinus Node disease
  • Sinus Tachycardia
  • Sinus arrhythmia
  • Sitagliptin 💊
  • Sitosterolemia
  • Sjögren’s syndrome
  • Skin Infections due to Fungi 🦠
  • Skin Pathology and Description and Examination
  • Skin Treatments
  • Skin Ulcers
  • Skin and soft tissue and bone infections ✅
  • Skin or subcutaneous lump
  • Skull Anatomy
  • Sleep physiology
  • Slipped Upper Femoral Epiphysis (SUFE)
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  • Download the amazing global Makindo app: ✅ Means NICE/National Guidelines 2026 compliant Android | Apple
    MEDICAL DISCLAIMER: Educational use only. Not for diagnosis or management. See below for full disclaimer.

    Surgery Revision Guide ✅

    🔪 Surgery is anatomy plus physiology under time pressure. Start with: is the patient unstable?, is there sepsis, bleeding, ischaemia, obstruction or perforation?, and does this need theatre, radiology, ICU or conservative treatment? For exams and clinical work, the surgical mindset is simple: resuscitate first, diagnose in parallel, control the source, and reassess repeatedly.

    🧠 Surgical patternDo not miss
    Severe abdominal pain + peritonismPerforation, ischaemia, appendicitis, ruptured AAA
    Vomiting + distension + constipationBowel obstruction
    Pain out of proportionMesenteric ischaemia, necrotising fasciitis, compartment syndrome
    Trauma + shockHaemorrhage until proven otherwise
    Head injury + falling GCSIntracranial bleed, raised ICP, hypoxia/hypotension
    Back pain + bladder/saddle symptomsCauda equina or spinal cord compression
    ✅ 1. Core Surgical Principles
    🚨 1.1 ABCDE First
    • A — Airway: obstruction, aspiration risk, cervical spine protection in trauma.
    • B — Breathing: oxygenation, pneumothorax, haemothorax, flail chest, aspiration, sepsis-related respiratory failure.
    • C — Circulation: haemorrhage, sepsis, dehydration, third-spacing, arrhythmia, shock.
    • D — Disability: GCS/AVPU, pupils, glucose, pain, delirium, head injury.
    • E — Exposure: abdomen, wounds, hernias, groins, back, perineum, temperature, safeguarding signs.

    🧠 Exam pearl: In surgery, a CT scan is not a resuscitation tool. If the patient is unstable, manage ABCDE, call senior help and consider immediate source control rather than sending an unsafe patient to imaging.

    🧪 1.2 Core Surgical Investigations
    • FBC: anaemia, infection, platelets.
    • U&E: dehydration, AKI, obstruction, vomiting-related electrolyte disturbance.
    • LFTs: biliary obstruction, hepatitis, sepsis, liver injury.
    • CRP: inflammation/infection trend, but can lag early.
    • Coagulation: bleeding, liver disease, anticoagulation, theatre planning.
    • Group and save/crossmatch: bleeding, trauma, ectopic, ruptured AAA, major surgery.
    • VBG/ABG with lactate: shock, sepsis, ischaemia, respiratory failure.
    • Urinalysis and pregnancy test where relevant.
    • Imaging: X-ray, ultrasound, CT, MRI or interventional radiology depending on diagnosis and stability.
    🧯 1.3 Source Control
    • Drain pus: abscess, empyema, infected collections.
    • Remove dead tissue: necrotising fasciitis, bowel necrosis, debridement.
    • Stop bleeding: pressure, surgery, endoscopy, interventional radiology.
    • Relieve obstruction: NG tube, catheter, stent, surgery, decompression.
    • Repair perforation: bowel perforation, perforated ulcer, traumatic injury.

    🚨 Safety pearl: Antibiotics help sepsis, but they do not replace source control. A perforated bowel, infected obstructed kidney or necrotising fasciitis needs mechanical control of the problem.

    🧰 2. Perioperative Care
    🩺 2.1 Pre-operative Assessment
    • Clarify indication, urgency, expected benefit and alternatives.
    • Assess comorbidities: cardiorespiratory disease, diabetes, CKD, anticoagulation, frailty, cognition, nutrition.
    • Review medications: anticoagulants, antiplatelets, steroids, diabetic drugs, ACEi/ARB, SGLT2 inhibitors, immunosuppressants.
    • Check allergies, airway risk, previous anaesthetic issues, VTE risk and infection risk.
    • Optimise: fluids, electrolytes, anaemia, sepsis, glucose, pain, nutrition and consent.
    • In emergency surgery, optimise what is possible without dangerous delay.
    📝 2.2 Consent
    • Explain diagnosis, uncertainty, treatment options and no-treatment option.
    • Discuss material risks: those a reasonable person in the patient’s position would consider significant.
    • Cover common and serious risks, including bleeding, infection, pain, scarring, VTE, organ injury, conversion to open surgery, stoma and death where relevant.
    • Assess capacity and support shared decision-making.
    • Document discussion clearly, including patient priorities and questions.
    🛡️ 2.3 Post-operative Care
    • ABCDE assessment for any deteriorating post-op patient.
    • Common problems: bleeding, sepsis, atelectasis, pneumonia, PE, MI, AKI, ileus, urinary retention, delirium and pain.
    • Monitor observations, urine output, drain output, wound, pain, bowels, glucose and bloods.
    • Encourage mobilisation, VTE prophylaxis, breathing exercises and early nutrition where appropriate.
    • Escalate early if tachycardia, hypotension, fever, rising lactate, oliguria, worsening pain or confusion.
    Post-op timingCommon causes of fever/deterioration
    HoursAtelectasis, transfusion reaction, bleeding, aspiration
    Day 1–3Pneumonia, UTI, line infection, early leak, DVT/PE
    Day 3–7Wound infection, intra-abdominal collection, anastomotic leak
    LaterAbscess, VTE, wound dehiscence, C. difficile, late leak
    🍽️ 3. Acute Abdomen
    🔍 3.1 Surgical Abdominal Pain Approach
    • Site: RUQ, epigastric, RIF, LIF, loin, suprapubic, generalised.
    • Onset: sudden, gradual, colicky, constant, migrating.
    • Associated symptoms: vomiting, distension, constipation, diarrhoea, bleeding, urinary symptoms, fever, jaundice.
    • Peritonism: guarding, rebound, percussion tenderness, pain on movement.
    • Shock or sepsis changes priority: resuscitate and call senior help.
    • Pregnancy test in reproductive-age patients with abdominal pain.
    📍 3.2 Pain Location Differentials
    SiteImportant differentials
    RUQBiliary colic, cholecystitis, cholangitis, hepatitis, liver abscess, pneumonia
    EpigastricPeptic ulcer, pancreatitis, MI, biliary disease, AAA
    RIFAppendicitis, Crohn’s, ovarian/testicular pathology, ectopic, renal colic
    LIFDiverticulitis, colitis, constipation, ovarian pathology, renal colic
    GeneralisedPerforation, obstruction, ischaemia, peritonitis, DKA, sepsis
    Loin-to-groinRenal colic, pyelonephritis, AAA, testicular/ovarian pathology

    🧠 Exam pearl: Pain that becomes generalised with guarding suggests local inflammation has progressed to peritonitis. That is a surgical escalation point.

    🪱 4. Appendicitis and Right Iliac Fossa Pain
    • Appendicitis classically starts with vague periumbilical pain that migrates to the right iliac fossa.
    • Associated features: anorexia, nausea, vomiting, low-grade fever and localised tenderness.
    • Signs: McBurney point tenderness, guarding, rebound, Rovsing sign, psoas sign, obturator sign.
    • Children, older adults and pregnancy can present atypically.
    • Differentials: gastroenteritis, mesenteric adenitis, Crohn’s, Meckel’s diverticulitis, ovarian torsion/cyst, ectopic pregnancy, UTI, renal colic.
    • Investigations: FBC, CRP, urine dip, pregnancy test, imaging depending on age/sex/local pathway.
    • Management: analgesia, fluids, antibiotics if indicated, appendicectomy or conservative pathway depending on case and local policy.

    ⚠️ Clinical pearl: Vomiting before pain makes appendicitis less likely; pain before vomiting is more typical. But do not rely on one feature alone.

    🪨 5. Gallstones and Biliary Surgery

    NICE CG188 covers diagnosis and management of gallstone disease in adults, including gallbladder and common bile duct stones.

    🪨 5.1 Biliary Colic
    • Intermittent RUQ/epigastric pain, often after fatty meals, caused by transient cystic duct obstruction.
    • Pain may radiate to right shoulder/scapula.
    • Usually no fever or marked inflammatory response.
    • Ultrasound shows gallstones; LFTs may be normal unless duct obstruction.
    • Definitive management is usually elective laparoscopic cholecystectomy if symptomatic.
    🔥 5.2 Acute Cholecystitis
    • Persistent RUQ pain, fever, raised inflammatory markers and Murphy sign.
    • Usually due to gallstone impaction in cystic duct.
    • Management: analgesia, antibiotics, IV fluids, early laparoscopic cholecystectomy where suitable.
    • High-risk patients may need gallbladder drainage.
    🟡 5.3 Choledocholithiasis and Cholangitis
    • Common bile duct stones can cause jaundice, cholestatic LFTs, pancreatitis or cholangitis.
    • Cholangitis: fever, jaundice and RUQ pain; severe cases cause hypotension/confusion.
    • Management: resuscitation, blood cultures, antibiotics and urgent biliary decompression, commonly ERCP.
    • MRCP or EUS may be used to assess duct stones in stable patients.
    🔥 5.4 Acute Pancreatitis
    • Common causes: gallstones and alcohol.
    • Features: severe epigastric pain radiating to back, vomiting, raised lipase/amylase.
    • Management: fluids, analgesia, antiemetics, oxygen if needed, nutrition, severity assessment and treat cause.
    • Complications: necrosis, pseudocyst, infected collections, ARDS, AKI, shock.
    • Gallstone pancreatitis may need ERCP if cholangitis or persistent obstruction.
    🚧 6. Bowel Obstruction and Ileus
    🚧 6.1 Small Bowel Obstruction
    • Features: colicky abdominal pain, vomiting, distension and constipation/obstipation.
    • Common causes: adhesions, hernia, Crohn’s disease, tumour, volvulus.
    • High obstruction causes early vomiting; distal obstruction causes more distension.
    • Examine hernial orifices carefully.
    • Initial management: nil by mouth, IV fluids, NG tube if vomiting/distended, analgesia, antiemetics, catheter/urine monitoring, CT to define cause and complications.
    • Red flags for strangulation/ischaemia: fever, tachycardia, peritonism, continuous pain, raised lactate, metabolic acidosis.
    🚧 6.2 Large Bowel Obstruction
    • Features: abdominal distension, absolute constipation, pain, later vomiting.
    • Common causes: colorectal cancer, volvulus, diverticular stricture.
    • Caecal diameter matters because risk of perforation increases with marked distension.
    • Management depends on cause: resuscitation, CT, decompression/stenting/surgery.
    🌀 6.3 Volvulus
    • Sigmoid volvulus: older/frail or neuropsychiatric patients, massive distension, “coffee bean” sign.
    • Caecal volvulus: younger than sigmoid group, congenital mobility, obstruction.
    • Sigmoid volvulus may be managed with endoscopic decompression if no peritonitis/ischaemia, followed by definitive planning.
    • Peritonitis, perforation or ischaemia needs surgery.
    🛌 6.4 Ileus
    • Functional bowel paralysis without mechanical obstruction.
    • Causes: post-op state, opioids, electrolyte disturbance, sepsis, inflammation, retroperitoneal pathology.
    • Management: treat cause, reduce opioids, correct electrolytes, mobilise, NG tube if significant vomiting/distension.
    🧱 7. Colorectal Surgery
    🔥 7.1 Diverticulitis
    • Inflammation/infection of diverticula, usually left-sided in Western populations.
    • Features: left iliac fossa pain, fever, altered bowel habit, raised inflammatory markers.
    • Complications: abscess, perforation, fistula, obstruction, stricture, bleeding.
    • CT abdomen/pelvis helps confirm diagnosis and detect complications.
    • Management ranges from oral antibiotics/observation to IV antibiotics, drainage or surgery depending on severity.
    🎗️ 7.2 Colorectal Cancer
    • Symptoms: change in bowel habit, rectal bleeding, iron deficiency anaemia, weight loss, abdominal pain, obstruction.
    • Right-sided cancers often present with anaemia and occult bleeding.
    • Left-sided cancers often present with altered bowel habit, visible bleeding or obstruction.
    • Investigations: FIT in symptomatic pathways, colonoscopy with biopsy, CT staging, MRI rectum for rectal cancer.
    • Management: surgery, chemotherapy, radiotherapy and stoma planning depending on site/stage.
    🩸 7.3 Lower GI Bleeding
    • Causes: diverticular bleeding, angiodysplasia, haemorrhoids, colorectal cancer, IBD, ischaemic colitis.
    • Assess haemodynamic stability; massive fresh rectal bleeding can be from upper GI source.
    • Investigations: FBC, clotting, group/crossmatch, CT angiography if active significant bleeding, endoscopy when appropriate.
    🩹 7.4 Perianal Disease
    • Haemorrhoids: painless bright red bleeding, itching, prolapse.
    • Anal fissure: severe pain on defecation with bright bleeding; posterior midline common.
    • Perianal abscess: painful swelling, fever; needs incision and drainage.
    • Fistula-in-ano: chronic discharge/opening, often after abscess; consider Crohn’s disease if complex/recurrent.
    🩸 8. Upper GI Surgery
    🔥 8.1 Peptic Ulcer Complications
    • Bleeding: haematemesis, melaena, anaemia, shock.
    • Perforation: sudden severe epigastric pain, rigid abdomen, free air under diaphragm.
    • Gastric outlet obstruction: vomiting, early satiety, weight loss, succussion splash.
    • Management of perforation: resuscitation, antibiotics, PPI, urgent surgery or selected conservative approach in very specific cases.
    🎗️ 8.2 Oesophagogastric Cancer
    • Oesophageal cancer: progressive dysphagia, weight loss, regurgitation, hoarseness.
    • Gastric cancer: weight loss, early satiety, dyspepsia, anaemia, vomiting.
    • Risk factors: smoking, alcohol, Barrett’s oesophagus, obesity, H. pylori, atrophic gastritis, family history.
    • Diagnosis: endoscopy with biopsy; staging with CT/PET/EUS/laparoscopy depending on tumour.
    • Management: surgery, chemotherapy, radiotherapy, stenting or palliative care depending on stage/fitness.
    🚑 8.3 Acute Mesenteric Ischaemia
    • Classically causes severe pain out of proportion to examination early.
    • Risk factors: AF, atherosclerosis, low-flow states, vasoconstrictors, thrombophilia.
    • Late signs: peritonitis, bloody diarrhoea, shock, high lactate.
    • Requires urgent CT angiography, resuscitation, broad-spectrum antibiotics and vascular/general surgical input.

    🚨 Exam pearl: Pain out of proportion in the abdomen is mesenteric ischaemia until proven otherwise, especially in AF or vascular disease.

    🧱 9. Hernias
    • Hernia = protrusion of tissue through a defect in the containing wall.
    • Reducible: contents can be returned.
    • Incarcerated/irreducible: cannot be reduced.
    • Obstructed: bowel lumen blocked within hernia.
    • Strangulated: blood supply compromised — surgical emergency.
    HerniaTypical clue
    Indirect inguinalPasses through deep ring; can enter scrotum; common in younger males
    Direct inguinalThrough posterior wall of inguinal canal; older males
    FemoralBelow and lateral to pubic tubercle; higher strangulation risk; commoner in women
    Umbilical/paraumbilicalAt/near umbilicus; obesity, pregnancy, ascites
    IncisionalThrough previous surgical scar

    🚨 Safety pearl: A painful irreducible hernia with vomiting, fever, skin changes or systemic illness is strangulated until proven otherwise — urgent surgery review.

    🩹 10. Skin, Soft Tissue and Breast Surgery
    🦠 10.1 Abscess and Cellulitis
    • Abscess: collection of pus; fluctuant, tender, localised swelling.
    • Definitive treatment is incision and drainage when mature/appropriate.
    • Antibiotics alone often fail if pus is not drained.
    • Cellulitis: spreading skin infection; manage with antibiotics and treat portal of entry.
    • Necrotising fasciitis: pain out of proportion, rapid progression, systemic toxicity, bullae/necrosis/crepitus; urgent debridement.
    🎗️ 10.2 Breast Lump
    • Triple assessment: clinical examination, imaging and tissue diagnosis.
    • Benign causes: fibroadenoma, cyst, fat necrosis, abscess, mastitis.
    • Malignancy red flags: hard irregular fixed lump, skin tethering, nipple inversion, blood-stained discharge, peau d’orange, axillary nodes.
    • Inflammatory breast cancer can mimic mastitis but does not settle with antibiotics.
    🍼 10.3 Mastitis and Breast Abscess
    • Mastitis: painful red breast, fever, flu-like symptoms; common in breastfeeding.
    • Continue milk removal if breastfeeding unless advised otherwise.
    • Abscess: focal fluctuant mass or persistent symptoms despite antibiotics; ultrasound and drainage may be needed.
    🧯 11. Vascular Surgery
    🩸 11.1 Acute Limb Ischaemia
    • Six Ps: pain, pallor, pulselessness, paraesthesia, paralysis, perishingly cold.
    • Causes: embolus from AF, thrombosis on atherosclerotic disease, graft occlusion, trauma.
    • Paralysis and anaesthesia indicate threatened limb and need immediate action.
    • Management: urgent vascular referral, analgesia, IV heparin if not contraindicated, imaging/revascularisation depending on limb viability.
    💥 11.2 Abdominal Aortic Aneurysm
    • Risk factors: age, male sex, smoking, hypertension, family history.
    • Rupture: abdominal/back pain, hypotension/collapse, pulsatile mass — classic triad often incomplete.
    • Do not delay vascular surgery referral for imaging in unstable suspected rupture.
    • Stable patients usually need CT angiography for planning.
    🦵 11.3 Peripheral Arterial Disease
    • Intermittent claudication: reproducible exertional muscle pain relieved by rest.
    • Critical limb-threatening ischaemia: rest pain, tissue loss, gangrene or non-healing ulcer.
    • Management: smoking cessation, antiplatelet/statin, exercise therapy, diabetes/BP control, revascularisation if severe.
    🩸 11.4 Varicose Veins and Venous Disease
    • Venous insufficiency causes aching, heaviness, oedema, eczema, pigmentation and ulcers.
    • Venous ulcers usually occur around the gaiter area and need compression if arterial supply adequate.
    • Check ABPI before compression therapy.
    🚑 12. Trauma: Major Trauma and ATLS Principles

    NICE NG39 covers rapid identification and early management of major trauma in pre-hospital and hospital settings, with the aim of reducing death and disability from serious injury.

    🚨 12.1 Trauma Primary Survey
    • C-spine: protect cervical spine when mechanism/risk suggests injury.
    • Airway: obstruction, facial trauma, blood/vomit, GCS impairment.
    • Breathing: tension pneumothorax, open pneumothorax, massive haemothorax, flail chest.
    • Circulation: haemorrhage control, pelvic binder, tourniquet/pressure, IV/IO access, major haemorrhage protocol.
    • Disability: GCS, pupils, glucose, limb movement.
    • Exposure: fully examine front/back while preventing hypothermia.
    🩸 12.2 Haemorrhagic Shock
    • In trauma, shock is haemorrhage until proven otherwise.
    • Bleeding sites: chest, abdomen, pelvis, long bones, external bleeding and floor.
    • Management: direct pressure/tourniquet, pelvic binder, blood products, tranexamic acid if within appropriate timeframe, warming and rapid source control.
    • Avoid excessive crystalloid causing dilutional coagulopathy and hypothermia.
    • Use balanced transfusion guided by major haemorrhage protocol.
    🫁 12.3 Life-Threatening Chest Injuries
    InjuryCluesImmediate principle
    Tension pneumothoraxSevere distress, hypotension, unilateral absent breath soundsImmediate decompression, then chest drain
    Open pneumothoraxSucking chest woundOcclusive dressing, chest drain
    Massive haemothoraxShock, reduced breath sounds, dull percussionChest drain, blood, thoracic surgery
    Flail chestParadoxical segment, pain, respiratory failureAnalgesia, oxygen/ventilation support
    Cardiac tamponadeShock, raised JVP, muffled heart soundsUrgent thoracic/trauma intervention
    🦴 12.4 Pelvic and Long Bone Trauma
    • Pelvic fractures can cause massive occult haemorrhage.
    • Apply pelvic binder early if pelvic injury suspected in unstable trauma.
    • Femoral shaft fractures can bleed significantly into thigh.
    • Open fractures require antibiotics, tetanus assessment, sterile dressing, splintage and urgent orthopaedics.
    🧊 12.5 Trauma Triad of Death
    • Hypothermia, acidosis and coagulopathy worsen each other.
    • Prevention: warming, haemorrhage control, balanced transfusion, avoid excess crystalloid, correct calcium and clotting abnormalities.

    🚨 Exam pearl: The “floor” is a hidden bleeding site — a trauma patient can lose their circulating volume externally before arrival.

    🧠 13. Neurosurgery and Head Injury

    NICE NG232 covers assessment and early management of head injury in babies, children, young people and adults, including when urgent imaging or specialist referral is needed.

    🧠 13.1 Head Injury Assessment
    • Record mechanism, loss of consciousness, amnesia, vomiting, seizure, anticoagulants/antiplatelets, alcohol/drugs and safeguarding concerns.
    • Assess GCS with components, pupils, focal neurology, skull signs and cervical spine risk.
    • Check glucose if reduced consciousness.
    • Repeated observations matter because deterioration can occur after an initially lucid period.
    • Escalate for falling GCS, unequal pupils, new focal deficit, repeated vomiting, seizure or signs of skull fracture.
    🩸 13.2 Extradural, Subdural and Subarachnoid Blood
    BleedTypical clueCT pattern
    Extradural haematomaTemporal trauma, lucid interval, middle meningeal arteryBiconvex/lens-shaped, does not cross sutures
    Subdural haematomaElderly, alcohol, anticoagulation, bridging veinsCrescent-shaped, can cross sutures
    Subarachnoid haemorrhageThunderclap headache, meningism, collapseBlood in basal cisterns/sulci
    Intracerebral contusionCoup/contrecoup injuryPatchy haemorrhagic bruising
    🧠 13.3 Raised Intracranial Pressure
    • Features: headache, vomiting, papilloedema, reduced consciousness, sixth nerve palsy.
    • Cushing response: hypertension, bradycardia and irregular breathing — late sign.
    • Management principles: airway/oxygenation, avoid hypotension, head elevation, treat seizures/fever, urgent imaging and neurosurgical input.
    • Hyperosmolar therapy or decompression may be needed in specialist settings.
    🧠 13.4 Concussion
    • Mild traumatic brain injury with transient neurological dysfunction.
    • Symptoms: headache, dizziness, nausea, fatigue, poor concentration, memory problems, sleep disturbance, mood change.
    • Give clear return precautions and graduated return to work/sport/school.
    • Second impact before recovery can be dangerous; avoid contact sport until medically cleared.

    🚨 Safety pearl: A falling GCS after head injury is an emergency. Protect airway, prevent hypoxia/hypotension and involve neurosurgery/trauma team early.

    🧠 14. Spine, Cauda Equina and Neurosurgical Infection
    🚨 14.1 Cauda Equina Syndrome
    • Compression of lumbosacral nerve roots causing bladder, bowel, sexual and saddle sensory dysfunction.
    • Red flags: urinary retention, reduced urinary sensation, saddle anaesthesia, faecal incontinence, bilateral sciatica, progressive weakness.
    • Requires emergency MRI and spinal surgical referral.
    • Do not reassure based only on normal anal tone; symptoms and bladder function matter.
    🧱 14.2 Spinal Cord Compression
    • Causes: metastatic cancer, epidural abscess, trauma, disc prolapse, haematoma.
    • Features: back pain, limb weakness, sensory level, hyperreflexia, bladder/bowel dysfunction.
    • Malignant cord compression often causes night/rest pain and progressive neurology.
    • Urgent MRI whole spine and specialist input are needed.
    🦠 14.3 Brain Abscess and Subdural Empyema
    • Can arise from sinusitis, otitis media, dental infection, endocarditis, neurosurgery or immunosuppression.
    • Features: headache, fever, focal neurology, seizure, raised ICP.
    • Management: urgent imaging, blood cultures, IV antibiotics and neurosurgical drainage depending on size/site.
    💧 14.4 Hydrocephalus and Shunts
    • Hydrocephalus causes ventriculomegaly from CSF flow/absorption problem.
    • Features: headache, vomiting, papilloedema, reduced consciousness; infants may have increasing head circumference/bulging fontanelle.
    • VP shunt complications: blockage, infection, over-drainage.
    • Shunt malfunction can deteriorate rapidly and needs urgent neurosurgical review.
    🧪 15. Surgical Sepsis and Antibiotics
    • Surgical sepsis often needs source control: drain, debride, resect, decompress or repair.
    • Sepsis signs: fever/hypothermia, tachycardia, tachypnoea, hypotension, confusion, oliguria, raised lactate.
    • Take cultures if this does not delay antibiotics.
    • Use antibiotics according to local policy and likely source: biliary, bowel, urinary, skin/soft tissue, chest, line.
    • Reassess after antibiotics: if still deteriorating, ask “where is the undrained pus or uncontrolled source?”
    SourcePossible control method
    Appendix perforationAppendicectomy/washout/drainage depending on case
    AbscessIncision/drainage or radiological drainage
    Obstructed infected bile ductERCP decompression
    Infected obstructed kidneyUreteric stent or nephrostomy
    Necrotising fasciitisUrgent radical debridement
    Anastomotic leakDrainage, antibiotics, surgery/endoscopy depending on severity
    🚨 16. Surgical Emergencies
    EmergencyKey cluesImmediate principle
    Ruptured AAACollapse, abdominal/back pain, pulsatile massVascular emergency, permissive resuscitation, theatre/EVAR
    Perforated viscusSudden severe pain, peritonism, free airResuscitate, antibiotics, urgent surgery
    Bowel ischaemiaPain out of proportion, AF, high lactateCTA, vascular/general surgery, resuscitate
    Strangulated herniaPainful irreducible hernia, obstruction, skin changesUrgent surgery
    Obstructed bowelVomiting, distension, constipationNBM, IV fluids, NG tube, CT, surgery review
    Necrotising fasciitisPain out of proportion, toxicity, bullae/necrosisImmediate surgery + antibiotics
    Compartment syndromeSevere pain on passive stretch, tense compartmentUrgent fasciotomy
    Tension pneumothoraxShock, respiratory distress, unilateral absent soundsImmediate decompression
    Extradural haematomaHead injury, lucid interval, deteriorationUrgent neurosurgical evacuation
    Cauda equinaSaddle anaesthesia, bladder dysfunctionEmergency MRI/spinal surgery
    📚 17. OSCE / Exam Pearls
    • Always assess ABCDE before narrowing the diagnosis.
    • Pregnancy test is essential in reproductive-age abdominal pain.
    • Pain out of proportion suggests ischaemia or necrotising infection.
    • Vomiting + distension + absolute constipation suggests bowel obstruction.
    • Peritonism means urgent surgical review.
    • Never forget hernial orifices in bowel obstruction.
    • In trauma, shock is haemorrhage until proven otherwise.
    • A falling GCS after head injury is a neurosurgical emergency.
    • Bilateral sciatica plus bladder/saddle symptoms is cauda equina until proven otherwise.
    • Antibiotics do not replace source control.
    📌 18. Quick Differentials Table
    PresentationImportant differentials
    RIF painAppendicitis, Crohn’s, ovarian torsion/cyst, ectopic, UTI, renal colic
    RUQ painBiliary colic, cholecystitis, cholangitis, hepatitis, liver abscess, pneumonia
    Epigastric painPancreatitis, perforated ulcer, MI, biliary disease, AAA
    Vomiting + distensionSBO, LBO, ileus, volvulus, pseudo-obstruction
    Fresh rectal bleedingHaemorrhoids, diverticular bleed, cancer, colitis, upper GI bleed if massive
    Shock after traumaChest, abdomen, pelvis, long bones, external bleeding, neurogenic shock
    Head injury deteriorationExtradural, subdural, contusion, raised ICP, seizure, hypoxia
    Back pain + neurologyCauda equina, cord compression, epidural abscess, fracture, disc prolapse
    📚 References
    • NICE. Major trauma: assessment and initial management. NG39.
    • NICE. Head injury: assessment and early management. NG232.
    • NICE. Gallstone disease: diagnosis and management. CG188.
    • NICE Clinical Knowledge Summary. Acute abdominal pain assessment.
    • Royal College of Surgeons guidance should be checked for emergency general surgery standards and local surgical pathways.
    • Local trauma network, neurosurgical, vascular, antimicrobial, major haemorrhage and perioperative policies should always be followed.
    ⚠️ Disclaimer

    This article is for medical education and exam revision. Clinical decisions should follow current local surgical, trauma, neurosurgical, vascular, antimicrobial, radiology, perioperative and major haemorrhage protocols, senior advice, NICE guidance and specialist network pathways. Surgical emergencies such as ruptured AAA, perforation, mesenteric ischaemia, strangulated hernia, necrotising fasciitis, major trauma, head injury deterioration and cauda equina syndrome require urgent senior input.


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