Related Subjects:
|Treponema
|Bejel (Endemic syphilis)
|Pinta
|Yaws (Frambesia)
|Syphilis
|Non gonococcal urethritis
|Gonococcal urethritis
|Lymphogranuloma Venereum (LGV)
|Chancroid
|Donovanosis
๐ About
- ๐งฌ Urethritis = inflammation of the urethra, most often caused by Chlamydia trachomatis.
- ๐ฆ Other pathogens: Ureaplasma urealyticum, Mycoplasma genitalium, Trichomonas vaginalis.
- ๐ฌ C. trachomatis is a small gram-negative bacterium and a leading cause of STIs worldwide.
๐ฉบ Clinical Presentation
- Men: Dysuria (painful urination) + urethral discharge (clear or mucoid; less purulent than gonorrhoea).
- Women: Often asymptomatic or mild dysuria, but can ascend โ cervicitis, salpingitis, pelvic inflammatory disease (PID) โ infertility risk.
- โ ๏ธ Untreated infections โ infertility, chronic pelvic pain, ectopic pregnancy (in females).
๐ Investigations
- ๐งซ Microscopy: >5 WBCs per high-power field (hpf) on Gram stain = diagnostic of urethritis.
- ๐ป NAAT / PCR (first-void urine): Gold standard for detecting Chlamydia & Mycoplasma.
- ๐ Partner notification / contact tracing is essential to prevent reinfection & reduce transmission.
๐ Management
- ๐จโโ๏ธ First-line (uncomplicated): Doxycycline 100 mg PO twice daily ร 7 days.
- ๐คฐ Pregnancy: Azithromycin 1 g PO single dose (safe, effective).
- โฑ๏ธ Abstain from sex until treatment course complete + partners treated.
- ๐งช Re-test in 3 months (reinfection common).