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Related Subjects: Asthma |Acute Severe Asthma |Exacerbation COPD |Pulmonary Embolism |Cardiogenic Pulmonary Oedema |Pneumothorax |Tension Pneumothorax |Respiratory (Chest) infections Pneumonia |Fat embolism |Hyperventilation Syndrome |ARDS |Respiratory Failure |Diabetic Ketoacidosis
PAO₂ = (Patm - PH₂O) FiO₂ - PaCO₂/RQ
At sea level, the alveolar PAO₂ is: PaO₂ = (760 - 47) 0.21 - 40/0.8 = 99.7 mm Hg.
A-a gradient = PAO₂ - PaO₂
The 3 major variables of the equation are the atmospheric pressure, amount of inspired oxygen, and levels of carbon dioxide. Each has an important clinical significance and can help explain different physiological and pathophysiological states.