| Iron Deficiency Anaemia ๐ชจ๐ |
- Pallor, fatigue, irritability ๐ฉ
- Poor feeding or growth delay in infants ๐
- Pica (craving dirt/ice) in severe cases ๐ง
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- CBC: microcytic, hypochromic anaemia
- Ferritin & iron: โ
- TIBC: โ
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- Oral iron (ferrous sulfate) ๐
- Iron-rich diet (red meat, greens, fortified cereals) ๐ฅฉ๐ฅฌ
- Monitor response with repeat CBC & ferritin
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| Megaloblastic Anaemia (Folate or B12 Deficiency) ๐๐ฅ |
- Pallor, lethargy, irritability ๐ด
- Glossitis (smooth red tongue) ๐
- Neurological features in B12 deficiency: poor coordination, developmental delay ๐ง
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- CBC: macrocytic anaemia (โ MCV)
- Serum folate & B12: โ
- Smear: hypersegmented neutrophils ๐ฌ
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- Folic acid supplements for folate deficiency
- B12 injections/oral for deficiency ๐
- Address malabsorption or dietary cause
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| Haemolytic Anaemia (e.g. Sickle Cell, Thalassaemia) ๐ฉธ๐งฌ |
- Chronic anaemia + jaundice ๐
- Sickle crises: severe pain ๐
- Splenomegaly, growth delay
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- CBC: normocytic/microcytic
- Reticulocytes: โ
- Hb electrophoresis: diagnostic โก
- Smear: sickled cells / target cells
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- Folic acid supplementation ๐
- Pain relief + hydration in crises ๐ง
- Blood transfusions if severe
- Hydroxyurea in sickle cell (โ crises)
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| Anaemia of Chronic Disease ๐ฅ |
- Pallor, fatigue, poor growth
- Associated with chronic infection, inflammation, or CKD
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- CBC: normocytic / mild microcytosis
- Ferritin: normal/high
- Serum iron & TIBC: โ
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- Treat underlying condition ๐ฉบ
- Iron usually ineffective unless co-deficient
- ESAs in CKD-related anaemia ๐
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| Aplastic Anaemia ๐ฆด |
- Pallor, lethargy
- Frequent infections ๐ค
- Easy bruising/bleeding (pancytopenia)
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- CBC: pancytopenia
- Bone marrow biopsy: hypocellular marrow ๐งซ
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- Supportive: transfusions, antibiotics
- Immunosuppressive therapy in some cases
- Bone marrow transplant in severe cases ๐ฑ
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