Makindo Medical Notes"One small step for man, one large step for Makindo" |
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📚 Related Subjects: Cardiogenic Pulmonary Oedema
Always check the BNF link here before prescribing. Glyceryl Trinitrate (GTN) is a cornerstone drug in acute cardiovascular care.
| Indication / Formulation | Details |
|---|---|
| 🚑 Acute Coronary Syndromes | Relief of chest pain with sublingual GTN (spray or tablet) |
| 💔 Left Ventricular Failure | Reduces preload and improves symptoms |
| 📈 Hypertensive Crises | Parenteral GTN infusion titrated to BP |
| 💨 GTN Spray | 1–2 sprays (400–800 mcg/dose) under the tongue as required |
| 💊 Sublingual Tablets | 500 mcg, 1–2 as required
⚠️ Sit down before use to avoid syncope |
| 🩹 Transdermal Patches | 5–20 mg per 24 h |
| 💉 IV Infusion | Start at 0.5 mg/hour; titrate to BP and symptoms (only if SBP >90 mmHg) |
| 💉 Syringe Driver | 50 mg GTN in 50 mL 0.9% NaCl → 0.5–10 mL/hour |
| 💉 Infusion Pump | 50 mg GTN in 500 mL 0.9% NaCl → 5–100 mL/hour |
| 🛑 Stop Criteria | Stop infusion if SBP <100 mmHg or patient becomes symptomatic with hypotension |