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Failure to Thrive (FTT) / Faltering Growth
โ ๏ธ Failure to thrive (FTT), or faltering growth, can result from social, medical, and feeding issues - often overlapping.
Always support parents and investigate thoroughly.
๐ Introduction
- FTT = insufficient weight gain or inappropriate weight loss in infancy/early childhood.
- Defined using centile spaces on UK WHO growth charts.
- Most often applied to children <2 years of age.
๐ FTT Defined As
- โฌ๏ธ Fall across 1+ centile space if birth weight < 9th percentile.
- โฌ๏ธ Fall across 2+ centile spaces if birth weight 9thโ91st percentile.
- โฌ๏ธ Fall across 3+ centile spaces if birth weight > 91st percentile.
- ๐ Current weight < 2nd percentile for age (any birth weight).
๐ผ Background
- Weight loss in early days is normal โ should regain by 3 weeks.
- Loss >10% of birth weight = dehydration until proven otherwise โ assess and treat.
- Failure to regain by 3 weeks โ consider referral to paediatrics.
๐ก Main Points
- FTT = slow physical development โ risk of short stature, behavioural issues, developmental delay.
- Causes: inadequate intake, malabsorption, โ metabolic demand, chronic disease.
- Severe cases โ neglect or abuse may be contributory.
- Early intervention prevents long-term consequences.
๐ Causes of Failure to Thrive / Poor Growth
- ๐ฝ๏ธ Nutritional
- Inadequate intake: poor feeding, neglect, dysphagia, food insecurity
- Malabsorption: coeliac disease, cystic fibrosis, chronic diarrhoea, food allergy, parasites
- Increased requirements: CHD, CLD, hyperthyroidism, infection, prematurity
- โ๏ธ Organic / Medical
- GI disorders: GERD, Crohnโs, ulcerative colitis, pyloric stenosis
- Endocrine: hypothyroidism, GH deficiency, diabetes, adrenal insufficiency
- Chronic infections: HIV, TB, recurrent UTIs, chronic otitis media, parasites
- ๐ง Psychosocial
- Neglect/abuse: food withheld, hostile environment
- Parentโchild interaction: maternal depression, poor bonding, misreading feeding cues
- ๐งฌ Genetic / Developmental
- Syndromes: Down, Turner, PraderโWilli, metabolic disorders, cleft palate
- Developmental delays: cerebral palsy, global delay โ feeding difficulty
๐ General Assessment
- ๐ Plot weight/height/head circumference on growth chart.
- ๐จโ๐ฉโ๐ง Midparental height calculation.
- ๐ผ Observe feeding behaviour, intake volume/frequency.
- ๐ Food diary.
- ๐ Consider psychosocial and environmental context.
๐งฉ Clinical Signs
- Persistent underweight / poor weight gain.
- Short stature for age.
- ๐ Irritability, fatigue, lethargy.
- ๐ Lack of social responsiveness.
- ๐ถ Delayed motor milestones.
- ๐ Learning and behavioural problems (later).
๐งช Investigations
- FBC, U&E, LFT, urine dipstick (UTI).
- Anti-TTG ยฑ IgA (coeliac screen).
- Directed tests: lead levels, sweat test, endocrine panel depending on suspicion.
๐ Management
- ๐ผ Support breastfeeding, formula if needed.
- ๐ฅ Dietitian input, supplements, high-calorie feeds.
- ๐จโ๐ฉโโ๏ธ Multidisciplinary approach (paeds, dietetics, social work).
- ๐ฅ Hospitalise if severe / unsafe / refractory.
- ๐ NG feeding if severe malnutrition or poor oral intake.
- โ ๏ธ Safeguarding: consider neglect/abuse if concerns raised.
๐ References