Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Both groups represent uncontrolled proliferation of blood cells, but they differ in **cell lineage, pathophysiology, presentation, and prognosis**. This comparison helps clarify the distinctions for exams and clinical practice.
Haematological malignancies can be organised by lineage (myeloid vs lymphoid) and by tempo (acute vs chronic). This structure is high-yield for exams and clinical reasoning.
Type | Acute 🔥 | Chronic 🕐 |
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Myeloid Lineage 🧬 |
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Lymphoid Lineage 🧪 |
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Feature | Myeloproliferative Disorders (MPDs) 🧬 | Lymphoproliferative Disorders (LPDs) 🧪 |
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Cell line affected | Myeloid stem cells → ↑ granulocytes, platelets, RBCs | Lymphoid lineage → ↑ B-cells, T-cells, NK cells |
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Clinical Features |
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