Makindo Medical Notes"One small step for man, one large step for Makindo" |
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π Gentamicin (OD dosing protocol) | |
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1 | βοΈ Determine weight β Use Ideal Body Weight (IBW) if BMI >30 (gentamicin does not distribute into adipose). β Treatment course should not exceed 7 days without microbiology advice. |
2 |
π§ͺ Estimate Creatinine Clearance (CrCl)
(140 β age) Γ weight (kg) Γ 1.23 (men) (140 β age) Γ weight (kg) Γ 1.04 (women)β οΈ Use IBW if obese. |
3 |
π Dosing (round down to nearest 40 mg):
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4 |
𧬠Monitor trough level (24 h after 1st dose):
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5 | β οΈ Do not prescribe in advance: β Never write up β48-hourly gentamicinβ β risk of being given 24-hourly in error. β Prescribe on a daily review basis only. |
6 | π§ Administration: Infuse in 100 mL 0.9% sodium chloride over 30 minutes. |
π‘ Clinical Pearls: β Gentamicin is highly nephrotoxic & ototoxic β monitor renal function closely. β Always document indication & planned duration. β In sepsis, ensure first dose is given immediately (donβt wait for levels).