Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Related Subjects: |Chronic liver disease |Cirrhosis |Alkaline phosphatase (ALP) |Liver Function Tests |Ascites Assessment and Management |Budd-Chiari syndrome |Autoimmune Hepatitis |Primary Biliary Cirrhosis |Primary Sclerosing Cholangitis |Wilson disease |Hereditary Haemochromatosis |Alpha-1 Antitrypsin (AAT) deficiency |Non alcoholic steatohepatitis (NASH) |Spontaneous Bacterial Peritonitis |Alcoholism and Alcoholic Liver Disease |Liver Transplantation
⚠️ Autoimmune Hepatitis (AIH) is a chronic inflammatory liver disease caused by immune-mediated attack on hepatocytes. Frequently associated with other autoimmune conditions such as Coombs-positive haemolytic anaemia, thyroiditis, and ITP. Untreated, AIH progresses to cirrhosis and hepatocellular carcinoma.
Features | Type 1 (Classical) | Type 2 |
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Prevalence | Most common | Less common, often aggressive |
Age | Adults + children | Children/young adults |
Autoantibodies |
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Presentation | Insidious onset, chronic hepatitis | Often acute hepatitis, esp. in girls |
Associations | Other autoimmune disorders (thyroid, RA, DM1) | Target antigen = CYP2D6 |