| 🌬 Acute Asthma Exacerbation |
- Wheeze, breathlessness, cough and chest tightness.
- Accessory muscle use, tachypnoea, tachycardia.
- Unable to complete sentences if severe.
- Life-threatening signs: silent chest, cyanosis, exhaustion, confusion, hypotension, SpO₂ <92%, normal/rising PaCO₂.
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- PEF compared with best/predicted if able.
- Oxygen saturation.
- ABG if SpO₂ <92%, life-threatening features or poor response.
- CXR only if pneumothorax, consolidation or other complication suspected.
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- Oxygen to target 94–98%.
- High-dose inhaled salbutamol via oxygen-driven nebuliser or MDI/spacer.
- Add nebulised ipratropium in severe/life-threatening asthma.
- Prednisolone 40–50 mg orally or IV hydrocortisone if unable to take oral.
- Consider IV magnesium sulfate for acute severe/life-threatening asthma with poor response.
- No sedatives. Escalate early to ICU if tiring, rising CO₂ or poor response.
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| 🫧 Pneumothorax |
- Sudden unilateral pleuritic chest pain and breathlessness.
- Reduced breath sounds and hyper-resonance on affected side.
- Tension pneumothorax: severe respiratory distress, hypotension, distended neck veins, tracheal deviation late.
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- Clinical diagnosis for tension pneumothorax - do not wait for X-ray.
- CXR for stable suspected pneumothorax.
- Bedside ultrasound may help in trauma/critical care.
- CT if uncertain or complex secondary pneumothorax.
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- Tension pneumothorax: immediate decompression followed by definitive chest drain.
- Small stable pneumothorax may be observed depending on size, symptoms and local BTS pathway.
- Symptomatic, large or secondary pneumothorax often needs aspiration or chest drain.
- Give oxygen if hypoxaemic and arrange respiratory/surgical follow-up.
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| 🩸 Pulmonary Embolism |
- Sudden breathlessness, pleuritic chest pain, haemoptysis or syncope.
- Tachycardia, tachypnoea, hypoxia.
- May have DVT symptoms: unilateral leg swelling/pain.
- Massive PE: hypotension, shock, collapse or cardiac arrest.
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- Use Wells score / clinical probability assessment.
- D-dimer if low probability and suitable.
- CTPA first-line imaging for many patients.
- V/Q scan if CTPA unsuitable, e.g. pregnancy/contrast issues depending on pathway.
- ECG may show sinus tachycardia or right heart strain; S1Q3T3 is uncommon.
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- Immediate admission if haemodynamically unstable.
- Start anticoagulation if PE likely and bleeding risk acceptable while awaiting imaging, according to local policy.
- LMWH, DOAC or unfractionated heparin depending on context, renal function and instability.
- Thrombolysis for massive/high-risk PE with haemodynamic instability if no contraindication.
- Consider embolectomy/catheter therapy if thrombolysis contraindicated or fails.
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| 🫁 Acute Respiratory Distress Syndrome |
- Severe hypoxaemia and respiratory distress.
- Often follows sepsis, severe pneumonia, aspiration, pancreatitis, trauma or transfusion.
- Bilateral infiltrates not fully explained by cardiac failure/fluid overload.
- Oxygen requirement escalates rapidly.
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- ABG: severe hypoxaemia; PaO₂/FiO₂ ratio used in ICU classification.
- CXR/CT: bilateral infiltrates.
- Sepsis screen and cultures where infection suspected.
- Echo/BNP if cardiogenic pulmonary oedema is a differential.
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- Critical care management.
- Treat underlying cause, e.g. antibiotics/source control in sepsis.
- Lung-protective ventilation with low tidal volumes and appropriate PEEP.
- Prone positioning in severe ARDS.
- Conservative fluid strategy once shock corrected; consider neuromuscular blockade/ECMO in selected severe cases.
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| 🫁 Acute COPD Exacerbation |
- Worsening breathlessness, cough, wheeze or sputum volume/purulence.
- Accessory muscle use and prolonged expiration.
- Confusion, drowsiness or cyanosis suggests respiratory failure.
- May be triggered by infection, pollution, PE, pneumothorax or heart failure.
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- Oxygen saturation and ABG if hypoxaemic, severe or drowsy.
- CXR to exclude pneumonia, pneumothorax or heart failure.
- FBC, U&E, CRP; sputum culture if severe or not responding.
- ECG if chest pain, arrhythmia or cardiac cause suspected.
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- Controlled oxygen target usually 88–92%.
- Nebulised salbutamol and ipratropium, air-driven if CO₂ retention risk with oxygen titrated separately.
- Oral prednisolone, commonly 30 mg daily for 5 days, according to local/NICE guidance.
- Antibiotics if increased sputum purulence or clinical bacterial infection.
- NIV if persistent respiratory acidosis despite optimal medical therapy.
- Escalate if worsening acidosis, exhaustion, reduced consciousness or NIV failure.
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| 🫁 Anaphylaxis with Respiratory Compromise |
- Rapid onset airway/breathing/circulation problems after trigger.
- Wheeze, stridor, throat tightness, tongue/lip swelling.
- Urticaria, flushing, angioedema may occur but can be absent.
- Hypotension, collapse, abdominal pain or vomiting may occur.
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- Clinical diagnosis - do not delay treatment.
- Monitor SpO₂, BP, ECG and respiratory status.
- Serum tryptase can support later diagnosis but is not needed acutely.
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- IM adrenaline immediately into anterolateral thigh; repeat if needed.
- Call for help, lie patient flat with legs raised unless breathing prevents this.
- High-flow oxygen and IV fluids for hypotension.
- Bronchodilator for persistent wheeze after adrenaline.
- Antihistamines may treat skin symptoms but are not first-line life-saving treatment.
- Routine corticosteroids are no longer recommended for initial emergency treatment.
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| 🍇 Foreign Body Aspiration / Choking |
- Sudden choking, coughing, gagging or stridor.
- Unable to speak/cough effectively in complete obstruction.
- Unilateral wheeze or reduced breath sounds if lodged bronchial foreign body.
- Children, older adults and neurological dysphagia are high-risk groups.
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- Clinical diagnosis in acute choking.
- CXR if stable; may show air trapping or atelectasis.
- Bronchoscopy is diagnostic and therapeutic.
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- Follow choking algorithm: encourage cough if effective; back blows/abdominal thrusts if ineffective cough in adults/children.
- Start CPR if unconscious.
- Urgent rigid bronchoscopy for persistent suspected airway foreign body.
- Oxygen and monitor for pneumonia, pneumothorax or airway oedema.
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| 🔥 Carbon Monoxide Poisoning |
- Headache, dizziness, nausea, weakness, confusion.
- Collapse, seizures, chest pain or coma in severe cases.
- Multiple people/pets affected suggests environmental exposure.
- Pulse oximetry may be falsely normal.
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- Carboxyhaemoglobin level by co-oximetry.
- ABG/VBG with lactate and pH.
- ECG and troponin if chest pain, older, pregnant or severe poisoning.
- Pregnancy test where relevant.
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- Remove from exposure and give 100% oxygen immediately.
- Discuss severe cases with TOXBASE/NPIS.
- Consider hyperbaric oxygen in selected severe poisoning, pregnancy, neurological features or cardiac involvement according to local/toxicology advice.
- Advise environmental safety check before returning home.
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| 🫁 Acute Epiglottitis / Supraglottitis |
- Severe sore throat, dysphagia, drooling, muffled voice.
- Stridor, respiratory distress or sitting forward.
- High fever may occur.
- Can occur in adults as well as children.
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- Clinical diagnosis; avoid distressing the patient.
- Flexible nasendoscopy only by experienced clinician in controlled setting.
- Do not force throat examination if unstable.
- Bloods/cultures after airway plan if safe.
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- Airway emergency: call ENT, anaesthetics and ICU early.
- Keep patient calm, upright and oxygenated.
- Prepare for controlled intubation or surgical airway if needed.
- IV antibiotics after airway safety addressed.
- ICU/HDU monitoring.
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| 🦠 Severe Pneumonia / Sepsis |
- Fever, cough, sputum, pleuritic pain and breathlessness.
- Confusion, hypotension, hypoxia or high respiratory rate suggests severe disease.
- May present atypically in frailty or older adults.
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- CXR, oxygen saturations, blood cultures if severe/sepsis.
- FBC, U&E, CRP, LFTs, lactate, ABG/VBG if severe.
- Sputum culture if productive/severe; viral testing depending on season/pathway.
- Severity scores such as CURB-65 can support decision-making.
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- Oxygen to target saturation.
- Sepsis pathway if sepsis suspected.
- Prompt antibiotics according to local community/hospital-acquired pneumonia guidance.
- IV fluids if shocked; cautious if heart failure/renal disease.
- Escalate to ICU for severe hypoxaemia, shock or respiratory failure.
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| 🌊 Acute Pulmonary Oedema |
- Severe breathlessness, orthopnoea and pink frothy sputum.
- Crackles, hypoxia, hypertension or hypotension.
- Often due to acute heart failure, ACS, arrhythmia or fluid overload.
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- CXR: pulmonary oedema.
- ECG and troponin if ACS suspected.
- BNP/NT-proBNP can support heart failure diagnosis.
- ABG/VBG if severe; U&E before/after diuresis.
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- Sit upright, oxygen if hypoxaemic.
- CPAP/NIV if severe respiratory distress or hypoxaemia.
- IV nitrates if hypertensive and no contraindication.
- IV diuretics if fluid overload.
- Treat trigger: ACS, arrhythmia, hypertensive emergency, valve disease or renal failure.
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