๐ค Saturday night palsy: weakness of wrist & finger extensors on waking after alcohol-induced sleep due to prolonged radial nerve compression.
๐งฉ Origin and Course
- Origin:
- Posterior cord of brachial plexus (C5โT1).
- Carries all posterior division fibres โ major motor to extensors.
- Course:
- Descends posterior to axillary artery โ radial groove of humerus.
- Winds laterally โ anterior to lateral epicondyle.
- Divides in proximal forearm into:
- Deep branch (posterior interosseous nerve).
- Superficial sensory branch.
๐ฟ Branches of the Radial Nerve
- Muscular branches: triceps, anconeus, brachioradialis, extensor carpi radialis longus.
- Cutaneous branches:
- Posterior cutaneous of arm.
- Inferior lateral cutaneous of arm.
- Posterior cutaneous of forearm.
- Deep branch (Posterior interosseous nerve) โ all forearm extensors.
- Superficial branch โ sensory to dorsum of hand (thumb, index, middle, radial half of ring finger; NOT fingertips).
โ๏ธ Functions
- Motor: elbow extension (triceps), wrist/finger extension, supination (supinator).
- Sensory: posterior arm & forearm, dorsum of hand (radial side).
๐จ Clinical
- Radial nerve palsy ("Saturday night palsy", "honeymoon palsy"):
- Wrist drop โ (cannot extend wrist/fingers).
- Sensory loss over dorsal hand.
- Usually temporary (resolves over weeks).
- Humeral shaft fracture:
- High risk of nerve injury in radial groove.
- Motor/sensory loss pattern as above.
- Compression injuries:
- Axilla: โcrutch palsyโ.
- Forearm: posterior interosseous entrapment (pure motor weakness).
๐งช Investigations
- Clinical exam: test wrist/finger extension, check sensory dorsum of hand.
- Electrophysiology: EMG, nerve conduction studies โ localise lesion.
- Imaging: X-ray for humeral fracture; MRI/US for entrapment or soft tissue mass.
๐ Causes
- Pressure palsy (sleep, crutches, prolonged positioning).
- Mononeuropathy: diabetes, alcohol, B12 deficiency.
- Trauma: humeral fracture, dislocation.
๐ Management
- Remove/avoid cause (e.g. avoid alcohol sleep posture, replace B12).
- Splint wrist to prevent contractures + OT/PT for recovery.
- Neuropathic pain management if present.
- Most palsies recover in weeksโmonths; poor prognosis if severe axonal loss on EMG.
๐ Exam tip: Wrist drop + humeral fracture = radial nerve injury. Posterior interosseous branch โ pure motor deficit without sensory loss.