Makindo Medical Notes"One small step for man, one large step for makindo" |
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Related Subjects: |Hyperuricaemia |Acute and Chronic Gout |Allopurinol |Rasburicase
Take great care in starting. There is a risk of SJS or TEN (Asian HLA-B*5801 allele) and there are also several potentially lethal drug interactions with Allopurinol and Azathioprine or Mercaptopurine or Ciclosporin. Side effects are rash, pruritus, cytopenia, diarrhoea, toxic epidermolysis and Stevens-Johnson syndrome.
Name | Starting Dose | Frequency | Route |
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Allopurinol | 100-200 mg (max dose 300 mg TDS) | OD | PO |
Allopurinol | 50 mg starting dose in Elderly | OD | PO |