| Energy / Fatigue |
Profound fatigue; post-exertional symptom exacerbation (PESE/PEM); unrefreshing sleep |
๐งญ Teach pacing & energy envelope; avoid fixed graded exercise. Sleep hygiene; screen for anaemia, thyroid, B12, ferritin, HbA1c; occupational/education adjustments. |
| Breathlessness / Chest |
Dyspnoea, chest tightness, cough; palpitations |
Vitals incl. SpOโ; CXR (โฅ12 wks if persistent), ECG; consider BNP if HF symptoms; inhaler trial if variable wheeze/cough. Safety-net for red flags. |
| Neurocognitive |
โBrain fogโ, poor concentration, headaches, dizziness |
Rule out depression, anxiety, sleep apnoea, migraine. Cognitive pacing, task chunking, screen/limit multitasking; consider work/study accommodations. |
| Autonomic / Orthostatic |
Orthostatic intolerance, tachycardia (possible PoTS), temperature dysregulation |
Active stand test; fluids 2โ3 L/day, โsalt if appropriate, compression stockings, slow position changes. Consider propranolol/ivabradine under specialist advice if PoTS suspected. |
| MSK / Pain |
Myalgia, arthralgia, deconditioning |
Gentle flexibility and symptom-contingent strengthening within energy envelope; heat/ice; simple analgesia; avoid NSAIDs if gastritis risk. |
| Mental health |
Anxiety, low mood, PTSD-like symptoms |
Validate; brief CBT-informed strategies; peer support; consider SSRIs/SNRIs if indicated; manage insomnia. |
| GI |
Nausea, diarrhoea, abdominal pain |
Hydration; low-FODMAP trial if IBS-like (short term, dietitian if possible); rule out red flags; treat reflux/IBS per guidelines. |
| ENT / Olfactory |
Hyposmia/anosmia, dysgeusia |
Olfactory training (twice daily, 12+ weeks); treat rhinitis/reflux if present. |