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Ezetimibe 💊
💊 Ezetimibe localises at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet.
About: Always check the BNF link here
- 🩺 Lipid-lowering agent often used as second-line to statins.
- 🚫 Blocks cholesterol uptake in the gut.
Indications
- 📉 Used with statins to reduce hypercholesterolaemia.
- 🧍 Can be given alone if statins are contraindicated or not tolerated.
- 💊 Adult dose: Ezetimibe 10 mg once daily.
Interactions
- ➕ When combined with a statin, may reduce cholesterol concentrations by an additional 20%.
Side Effects
- 🙂 Generally well tolerated and better tolerated than bile acid sequestrants.
- Occasional GI upset, fatigue, or headaches may occur.
References
| The content on this website is provided for educational and informational purposes only to support exam preparation (e.g., MLA, MRCP, USMLE) and learning. This is NOT medical advice, diagnosis, treatment, or professional guidance. It does not replace consultation with a qualified healthcare professional, official guidelines (e.g., NICE, GMC, BNF), or supervised clinical practice. Always verify information with current, authoritative sources. Makindo and its contributors accept no liability for any reliance on this content, including errors, omissions, or any resulting harm, loss, or consequences. By using this site, you agree to these terms. |
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