Makindo Medical Notes"One small step for man, one large step for Makindo" |
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β οΈ Safety notes: - There is evidence omeprazole may reduce the efficacy of clopidogrel (interaction remains under review). - Always ensure dyspepsia is not due to gastric or oesophageal cancer before starting treatment.
Always check the BNF link here.
| Indication | Details |
|---|---|
| π©Ή Duodenal Ulcer | Omeprazole 20 mg OD Γ 4 weeks (most heal in this time) |
| π©Ή Gastric Ulcer | Omeprazole 40 mg OD Γ 4β8 weeks |
| π₯ GORD | Omeprazole 20 mg OD Γ 4β8 weeks |
| π§ͺ Erosive Oesophagitis | Omeprazole 10β40 mg OD |
| π Upper GI Bleed |
Omeprazole
β’ 80 mg IV infusion in 250 mL 0.9% NaCl or 5% glucose over 60 min β’ Then 8 mg/hour (80 mg in 250 mL over 10 h) β’ Continue for 72 h (β 7 infusion bags, ~16 Γ 40 mg vials) |
| 𧬠ZollingerβEllison Syndrome | Omeprazole start 60β120 mg/day (individualise to response) |