Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Related Subjects: |CEA |ALP |LDH
π‘ With effective treatment, the overall five-year survival rate in testicular cancer is ~97%. Orchidectomy is both diagnostic and therapeutic. Discuss sperm banking early for men wishing to preserve fertility.
Feature | Seminoma | Non-Seminoma |
---|---|---|
Typical Age | 30β50 | 15β35 |
Tumour Markers | Ξ²-hCG β (10β20%), AFP normal | AFP β, Ξ²-hCG β, LDH β |
Spread | Lymphatic (late) | Early haematogenous (lung, liver) |
Prognosis | Excellent (>90% cure) | Variable, depends on stage/type |
Radiotherapy | Highly sensitive | Resistant |
Type | Examples | Notes |
---|---|---|
Mixed GCT | Seminoma + NSGCT | Behaves like NSGCT β treat accordingly |
Stromal | Leydig, Sertoli | May secrete hormones β gynaecomastia, precocious puberty |
Secondary | Lymphoma, metastatic deposits | Commonest >60 y/o; bilateral possible |