Gestational trophoblastic disease — molar pregnancy ⚠️ 🩺
🧠 Clinical mechanism: Abnormal trophoblastic proliferation includes complete and partial hydatidiform moles and rarely gestational trophoblastic neoplasia.
🔎 Recognise
- Bleeding in early pregnancy, suspicious ultrasound or unexpectedly high/persistent hCG after a pregnancy event.
🛟 First assessment and action
- Refer through early pregnancy/gynaecology specialist pathways; arrange appropriate follow-up and counselling through a designated trophoblastic centre.
🧪 Investigations and reassessment
- Ultrasound and serial hCG under specialist direction, with histopathology after evacuation where indicated.
⚠️ Pitfall / escalation
- Persistent hCG after treatment needs ongoing specialist surveillance; do not discharge solely because vaginal bleeding resolves.
UK reference: Primary NHS/NICE/RCOG/GMC source.
Editorial draft, 7 November 2026: targeted source-supported educational summary, NOT independent consultant/pharmacist verification or a treatment protocol. Follow up-to-date BNF, NICE and local NHS pathways.
Related: Miscarriage · Ectopic Pregnancy