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โ ๏ธ Editorial teaching card; not a prescribing instruction. Confirm current BNF/BNFC, SmPC, local formulary and specialist advice for any dose, route or formulation. Independent pharmacist sign-off pending.
Broad-spectrum IV carbapenem, usually reserved for severe infection when indicated by resistance, syndrome or specialist advice.
Carbapenems can markedly reduce valproate concentrations and precipitate seizures; seek urgent specialist advice for combined use.
UK references: NICE NG15 antimicrobial stewardship
Educational draft 4 November 2026; individual regimen and dose NOT clinically signed off.