| Download the amazing global Makindo app: โ Means NICE/National Guidelines 2026 compliant Android | Apple | |
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| MEDICAL DISCLAIMER: Educational use only. Not for diagnosis or management. See below for full disclaimer. |
โ ๏ธ Editorial teaching card; not a prescribing instruction. Confirm current BNF/BNFC, SmPC, local formulary and specialist advice for any dose, route or formulation. Independent pharmacist sign-off pending.
Trimethoprim plus sulfamethoxazole; specialist antimicrobial with important haematologic and metabolic interactions.
Bone marrow suppression, hyperkalaemia and serious rashes require prompt recognition; do not substitute routine UTI dosing for Pneumocystis treatment.
UK references: NHS SPS methotrexate interactions
Educational draft 4 November 2026; individual regimen and dose NOT clinically signed off.