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Neonatal jaundice — urgent features ⚠️ 👶
Neonatal jaundice — urgent features ⚠️ 👶
Unconjugated bilirubin can cross the immature blood–brain barrier at high levels, while prolonged conjugated jaundice may point to biliary obstruction or liver disease.
🔎 Recognise
Jaundice in the first 24 hours, poor feeding, lethargy, abnormal tone, pale stools or dark urine are red flags. Interpret bilirubin in relation to gestational age and exact postnatal hours.
🛟 First actions
For visible jaundice during the first 24 hours, arrange an urgent serum bilirubin measurement and neonatal review. Escalate a neurologically unwell infant immediately.
🧪 Investigations and reassessment
Use age-in-hours treatment charts and the correct serum/transcutaneous measurement pathway; investigate haemolysis, infection and prolonged jaundice with neonatal input.
⚠️ Common pitfalls and escalation
Do not estimate bilirubin numerically from skin colour or use a single fixed threshold at all ages. A well-appearing baby with prolonged jaundice still needs assessment for conjugated hyperbilirubinaemia.
UK reference: NICE CG98 neonatal jaundice. Focused editorial source check, 7 November 2026; this is not independent clinical or pharmacy sign-off. Verify current local policy, BNF/BNFC and specialist advice before treatment. Not a prescribing protocol.
Related guides: Neonatal death or cot death · Biliary atresia
| The content on this website is provided for educational and informational purposes only to support exam preparation (e.g., MLA, MRCP, USMLE) and learning. This is NOT medical advice, diagnosis, treatment, or professional guidance. It does not replace consultation with a qualified healthcare professional, official guidelines (e.g., NICE, GMC, BNF), or supervised clinical practice. Always verify information with current, authoritative sources. Makindo and its contributors accept no liability for any reliance on this content, including errors, omissions, or any resulting harm, loss, or consequences. By using this site, you agree to these terms. |
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